メディリッジ List of Products and Services

Mediridge Co., Ltd. offers services for the preparation of pathological specimens from experimental animals and human (clinical research) samples. We have a dedicated laboratory for animal specimens, capable of addressing the exploration of precancerous lesions and biomarkers, as well as analyses through animal experiments. The lab is staffed with pathologists who can diagnose human specimens, and we also have pathologists who can assess animal pathology, allowing us to meet requests for pathological diagnoses. 【Features】 ■ Dedicated laboratory for animal specimens ■ Capable of exploring precancerous lesions and biomarkers, and conducting analyses through animal experiments ■ Pathologists who can diagnose human specimens are present in the lab ■ Able to accommodate requests for pathological diagnoses *For more details, please refer to the PDF materials or feel free to contact us.

• Other contract services

At Mediridge Co., Ltd., we conduct tumor engraftment confirmation based on literature and experimental protocols. We can accommodate various requests, including drug administration experiments using generated animals, tumor passage (in vivo or in vitro), and ELISA measurements using serum. We also offer a contract service for various animal testing. Please feel free to contact us. 【Features】 ■ We accept tumor cell lines, implant them in mice, and confirm tumor engraftment. ■ We listen to customer requests and propose suitable protocols. ■ We conduct tests in accordance with laws and guidelines regarding animal welfare. ■ Animal husbandry is carried out in an SPF environment. *For more details, please refer to the PDF document or feel free to contact us.

• Animal cells
• Other Testing Contract

At Mediridge Co., Ltd., we carry out manufacturing tailored to our customers' needs, from research purposes to GMP production. The host organisms we can accommodate include E. coli, yeast, baculovirus, and mammalian cells (for transient expression and stable cell line culture). We conduct protein production in Japan, ranging from small to medium scale (2.5L to 50L) to large scale (500L and above). [Overview] ■ Production of proteins using E. coli and yeast (cultivation and purification) → GMP manufacturing is possible in Japan - 5L jar fermenter (2.5 to 3L batch) - 20L jar fermenter (10 to 13L batch) - 90L tank and tanks over 500L ◎ Temperature control is possible, such as lowering the temperature during IPTG induction. *For more details, please refer to the PDF materials or feel free to contact us.

• Other contract manufacturing

Mediridge Co., Ltd. offers the production of monoclonal antibodies (hybridomas) and polyclonal antibodies. The rights to the established hybridomas belong to the client. Secondary screening using the client's protocols, such as the sandwich ELISA method, is also available as an option. Please feel free to contact us. 【Features】 ■ The rights to the established hybridomas belong to the client ■ Short delivery time of 3 to 4 months ■ Reliable domestic production ■ Production using the lymph node method ■ Careful workmanship *For more details, please refer to the PDF document or feel free to contact us.

• Other contract manufacturing

At Mediridge Co., Ltd., we will take care of your hybridoma and carry out antibody production. The manufacturing methods are primarily based on the roller bottle method or the back culture method. Depending on the properties and yield of the antibodies, we can also accommodate methods such as the Integra cell line method, flask culture method, and WAVE culture method. 【Workflow】 ■ Cell awakening ■ (Serum-free adaptation) 2 to 4 weeks ・ If not adapted to serum-free conditions, adaptation to serum-free will be conducted ■ Large-scale culture 3 to 6 weeks ・ Scale-up culture will be performed using the specified method ■ Purification and analysis 2 to 4 weeks ・ If you require high-purity purification through affinity purification using Protein A or G, gel filtration purification is also possible. *For more details, please refer to the PDF document or feel free to contact us.

• Other contract manufacturing

Mediridge Co., Ltd. offers contract peptide synthesis and manufacturing services. We provide manufacturing tailored to our customers' needs, from research applications to production materials. In manufacturing applications, we conduct production of peptides for APIs and pharmaceuticals at cGMP grade. If you need peptide synthesis, please feel free to consult with Mediridge. 【Features】 ■ Synthesis for research applications is conducted safely and securely in Japan. ■ Capable of high-purity synthesis. ■ High-quality peptides made from quality raw materials. ■ Manufacturing tailored to our customers' needs. *For more details, please refer to the PDF materials or feel free to contact us.

• Peptide synthesis
• Other contract manufacturing

MediRidge Co., Ltd. manufactures high-purity, high-quality plasmid DNA. "We want to perform large-scale purification of plasmids, but we can't produce them effectively in large quantities." "We do not have the facilities for large-scale cultivation," etc. We respond to requests like the above. We offer contract manufacturing from 1 mg to several grams. Please feel free to contact us. 【Plasmid Manufacturing Grades】 ■ Standard Grade - Manufacturing of plasmids for general experimental use that do not require endotoxin control. ■ Endotoxin-Free Grade - Manufacturing of plasmids while controlling endotoxins. ■ GMP Grade - Manufacturing of plasmids using patented TFF membrane extraction filtration in a fully closed system in GMP-compliant facilities, while maintaining endotoxin and sterile conditions. *For more details, please refer to the PDF materials or feel free to contact us.

• Other contract manufacturing

Mediridge Co., Ltd. provides a wide range of services for the establishment of microbial and yeast-derived cell lines for biopharmaceutical development, from non-clinical trials to clinical sample analysis. Using new equipment and reliable technology, we conduct tests in compliance with GLP on the following items. In particular, for in vivo tests such as pharmacokinetics (PK) and toxicokinetics (TK) measurements, as well as immunogenicity (ADA) against drugs, we have BLS-2 facilities and offer advanced know-how and technology at reasonable prices. 【Main Testing Items】 ■ Bioassays and potency tests using cells ■ Custom host protein measurements ■ Lot release testing ■ Support for non-clinical and clinical trials ■ Binding quantification methods and immunological measurement methods, etc. *For more details, please refer to our catalog or feel free to contact us.

• Other Testing Contract
• Other contract services
• Other analysis and evaluation services

MediLidge Co., Ltd. provides a wide range of services from non-clinical trials for recombinant protein production and monoclonal antibody manufacturing to clinical sample analysis. Using new equipment and reliable technology, we conduct tests in compliance with GLP for the following items: 【Main Test Items】 ■ Validation of virus clearance ■ Custom host protein measurement ■ Bioassays and potency tests using cells ■ Lot release testing ■ Binding quantification methods and immunological measurement methods, etc. *For more details, please refer to our catalog or feel free to contact us.

• Other Testing Contract
• Other contract services
• Other analysis and evaluation services

Mediridge Co., Ltd. provides a wide range of services necessary for testing starting materials, testing at the time of product release, and non-clinical trials. Using new equipment and reliable technology, we conduct tests in compliance with GLP in the following areas: 【Main Testing Items】 ■ Bioassays and potency tests using cells ■ Non-clinical trials ■ R&D support services *For more details, please refer to our catalog or feel free to contact us.

• Other Testing Contract
• Other contract services
• Other analysis and evaluation services

Mediridge Co., Ltd. offers a wide range of services for our customers' vaccine development, from characterization of cell lines to characterization of virus seed lots and analysis of clinical samples. Using new equipment and reliable technology, we conduct tests in compliance with GLP for the following items: 【Main Test Items】 ■ Validation of virus clearance ■ Lot release testing ■ Potency testing ■ Custom host protein measurement ■ Bioassays and potency testing using cells, etc. *For more details, please refer to our catalog or feel free to contact us.

• Other Testing Contract
• Other contract services
• Other analysis and evaluation services

At Mediridge, we provide biological safety testing and analytical services required at various stages of biopharmaceutical development. We can accommodate a wide range of services, including efficacy confirmation, purity testing, equivalence/equivalence evaluation, and sterility testing of biopharmaceuticals. These testing services and assays are provided in compliance with global regulatory requirements such as JP, FDA, and EMA. Experienced scientists will design lot release programs tailored to the characteristics and specific requirements of biopharmaceuticals. 【Wide Range of Support】 ■ Biological Safety ■ Efficacy Confirmation ■ Equivalence/Equivalence Evaluation ■ Sterility Testing of Biopharmaceuticals *For more details, please refer to our catalog or feel free to contact us.

• Other Testing Contract
• Other contract services
• Other analysis and evaluation services

At Mediridge, we offer reliable virus clearance testing at reasonable prices. Virus clearance testing is required not only for biopharmaceuticals but also for the materials used in the manufacturing processes of biopharmaceuticals. Mediridge, as the exclusive agent for TFBS in Japan, will responsibly serve as the contact point for contract services related to virus clearance testing. 【Features】 ■ Compliance with international regulatory standards for pharmaceuticals (ICH, FDA, EMA, etc.) ■ GLP quality system: Compliant with GLP standards from Taiwan FDA, US FDA, OECD, etc. ■ Certified Quality Assurance personnel (QAU) responsible for process management reviews of each test ■ Tests designed to meet customer needs, with validation conducted ■ Consulting on relevant international regulations *For more details, please request materials or view the PDF data from the download section.

• Other Testing Contract
• Other analysis and evaluation services
• Hygiene Management

At Mediridge, we conduct tests in accordance with GLP and international regulatory guidelines to meet our customers' needs, ranging from preliminary tests of seed stocks to rigorous characterization assessments of cell banks. The testing is carried out at the Testing Facility of Bio Safety (TFBS), which is a part of the Development Center of Biotechnology (DCB) in Taiwan. If you require cell bank characterization analysis, please feel free to consult with Mediridge. 【Features】 ■ Compliance with GLP and international regulatory guidelines ICH (Q5A, Q5B, Q5D), JP, EP, USP ■ Development of accurate verification methods at low cost *For more details, please request our materials or view the PDF data available for download.

• Other analysis and evaluation services
• Other Testing Contract
• Other Contract Life Science Specialization