ケーナインラボ List of Products and Services

Enhancing the immune function of calves and preventing the onset of diseases! We aim to provide safe meat products. Here, we introduce our "patented technology" that strengthens the immune function of calves and prevents infections. This technology involves transferring activated T lymphocytes derived from other cows (mother cows, healthy cows) to newborn calves. Direct effects include strengthening the overall immunity of calves and preventing the onset of infections. Additionally, it is expected to reduce weak and underweight animals, improve productivity, and ultimately provide safe meat products, which are indirect benefits. Based on this technology, we anticipate the development of unique regenerative medicine products for large animals. Patents have been obtained in Japan, as well as in Australia, New Zealand, Canada, and Europe (United Kingdom, France, Germany, Netherlands). 【Technology Overview】 ■ Collaborative Research Institution: Rakuno Gakuen University ■ Patent Number: Patent No. 5006992 (JP5006992) ■ Invention Title: Immune Function Enhancer ■ Foreign Patents: Australia, New Zealand, Canada, Europe (United Kingdom, France, Germany, Netherlands) *For more details, please refer to the PDF materials or feel free to contact us. *We are currently seeking collaborative development partners for future regenerative medicine products.

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This document introduces the "Feline Immunodeficiency Provirus (proFIV) Qualitative Test" conducted by K9 Lab, which supports animal healthcare with advanced technology. When a cat is infected with the Feline Immunodeficiency Virus (FIV), the virus's genetic material integrates into the DNA of the white blood cells (the integrated virus is called a provirus). Since proviruses are not formed by the FIV vaccine, the test will only yield a positive result when a natural strain is present. This test is useful for determining the presence or absence of infection. The document provides detailed information on the characteristics and clinical significance of the test, as well as the replication methods of the Feline Immunodeficiency Virus. [Contents] - Characteristics and clinical significance of the test - Replication methods of the Feline Immunodeficiency Virus - Comparison of proviral gene testing, viral gene testing/antigen testing, and antibody testing - Q&A *For more details, please refer to the PDF document or feel free to contact us.

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This document introduces the "Feline Immunodeficiency Provirus (proFIV) Qualitative Test" conducted by K9 Lab, which supports animal healthcare with advanced technology. When a cat is infected with the Feline Immunodeficiency Virus (FIV), the virus's genetic material integrates into the DNA of white blood cells (the integrated virus is referred to as a provirus). Since proviruses are not formed by the FIV vaccine, the test will only yield a positive result if a natural strain is present. This test is useful for determining the presence or absence of infection. The document provides detailed information on the characteristics and clinical significance of the test, as well as the methods of Feline Immunodeficiency Virus propagation. [Contents] ■ Characteristics and clinical significance of the test ■ Methods of Feline Immunodeficiency Virus propagation ■ Comparison of proviral gene testing, viral gene testing/antigen testing, and antibody testing ■ Q&A *For more details, please refer to the PDF document or feel free to contact us.

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This document introduces the "Feline Immunodeficiency Virus (FIV) Quantitative Test" conducted by K9 Lab, which supports animal healthcare with advanced technology. This test measures the viral load in plasma using real-time PCR, providing information to predict the presence of the disease, its stage, and prognosis. It includes detailed information on the features of the test, its clinical significance, and a Q&A section. [Contents] - Features of the test and clinical significance - Q&A - Reference materials: Evidence *For more details, please refer to the PDF document or feel free to contact us.

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This document introduces the "Feline Coronavirus (FCoV) Gene Quantitative/Qualitative Test" conducted by K9 Lab, which supports animal healthcare with cutting-edge technology. The feline coronavirus gene test is useful for the definitive diagnosis of feline infectious peritonitis (FIP). The document provides detailed information on the features of the test, its clinical significance, and a Q&A section. [Contents] ■ Features of the test and clinical significance ■ Q&A ■ Reference materials *For more details, please refer to the PDF document or feel free to contact us.

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This document introduces the "BRAF gene mutation test for dogs (bladder transitional cell carcinoma and prostate cancer)" conducted by K9 Lab, which supports animal healthcare with advanced technology. In dogs with bladder transitional cell carcinoma and prostate cancer, mutations in the BRAF gene (homologous to human BRAF amino acid 600) are frequently present. In other tumors, the frequency of this mutation is low, and it is not detected in non-tumorous changes such as cystitis. Therefore, if a mutation is detected, it is highly likely that the cells in the sample are proliferating tumorally. The document provides detailed information on the characteristics of the test, its clinical significance, and a Q&A section. [Contents] ■ Characteristics of the test and clinical significance ■ Consider the BRAF gene mutation test in these situations ■ Evidence: Reference materials ■ Q&A *For more details, please refer to the PDF document or feel free to contact us.

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This document introduces the "Leptospira Gene Test" conducted by K9 Lab, which supports animal healthcare with advanced technology. This test detects all pathogenic Leptospira. Additionally, the gene test can be performed on both blood and urine samples, making it useful for definitive diagnosis. The document provides detailed information on the features of the test, its clinical significance, and a Q&A section. [Contents] - Features of the test and clinical significance - Q&A - Reference materials *For more details, please refer to the PDF document or feel free to contact us.

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This document introduces the "Lymphocyte Surface Marker Analysis (Immunological Testing for Lymphoma and Lymphocytic Leukemia)" conducted by K9 Lab, which supports animal medicine with advanced technology. This test clarifies whether the lymphocytes in the sample are proliferating tumorally and identifies whether the tumorigenic lymphocytes originate from T or B lymphocytes (T/B classification). It provides detailed information on the features of the test, its clinical significance, and includes a Q&A section. [Contents] ■ Features of the test and clinical significance ■ Consider lymphocyte surface marker analysis in the following situations ■ Q&A ■ Reference materials *For more details, please refer to the PDF document or feel free to contact us.

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This document introduces the "Clonality Analysis (genetic testing for lymphoma and lymphocytic leukemia)" conducted by K9 Lab, which supports animal medicine with cutting-edge technology. This test clarifies whether lymphocytes in the sample are proliferating monoclonally (tumorigenic proliferation) and identifies whether the tumor-derived lymphocytes originate from T or B lymphocytes. It provides detailed information on the features of the test, its clinical significance, and includes a Q&A section. [Contents] ■ Features of the test and clinical significance ■ When to consider clonality analysis ■ Evidence: Reference materials ■ Q&A *For more details, please refer to the PDF document or feel free to contact us.

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This document introduces the "c-kit gene mutation test (a test for predicting the efficacy of imatinib mesylate)" conducted by K9 Lab, which supports animal medicine with cutting-edge technology. This test clarifies whether there are mutations in the c-kit gene and predicts the efficacy of imatinib mesylate. It includes features of the test, clinical significance, and information on the MDR-1 gene mutation test. [Contents] ■ Features of the test and clinical significance ■ Types of mutations detected and prediction of imatinib mesylate efficacy ■ Q&A ■ Mechanism of action of imatinib ■ Reference materials ■ MDR-1 gene mutation test *For more details, please refer to the PDF document or feel free to contact us.

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This document provides information about the genetic tests conducted by K9 Lab. It introduces various genetic tests for animals, including "Clonality Analysis" for lymphoma and lymphoid leukemia, "Lymphocyte Surface Marker Analysis," and "Canine BRAF Gene Mutation Testing." 【Contents】 ■ Tests used for tumor diagnosis ■ Tests to predict the effectiveness of treatments ■ Genetic diseases and others ■ Infectious diseases *For more details, please refer to the PDF document or feel free to contact us.

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We will begin testing for the classification of feline immunodeficiency virus (FIV) subtypes. Recent studies suggest that FIV subtype B has lower pathogenicity compared to other subtypes and a reduced likelihood of developing AIDS. This document explains "Feline Immunodeficiency Virus and Subtypes." We provide a detailed introduction to FIV subtypes and their pathogenicity, as well as the antiviral mechanisms in cats and the viral infection factors, using diagrams and other materials. [Contents] ■ Feline Immunodeficiency Virus and Subtypes ■ FIV Subtypes and Pathogenicity ■ Antiviral Mechanisms in Cats and Viral Infection Factors ■ Comparison of Vif Activity by Subtype ■ Genetic Testing for FIV Subtype Classification ■ Q&A *For more details, please refer to the PDF document or feel free to contact us.

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This document contains information about the hereditary disease "Autosomal Dominant Polycystic Kidney Disease (ADPKD)," which is characterized by the formation of cysts that accumulate fluid in the kidneys (and in some cases, the liver and pancreas), as well as information on genetic testing. We introduce the analysis methods for genetic testing, detection rates for genetic testing and ultrasound examinations, and a Q&A section. [Contents] ■ Autosomal Dominant Polycystic Kidney Disease (ADPKD) and Genetic Testing ■ About Genetic Testing ■ Table 1. Mutation Rates of Persian Cats in Various Countries ■ Table 2. Detection Rates of Genetic Testing and Ultrasound Examinations ■ Q&A *For more details, please refer to the PDF document or feel free to contact us.

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Our company supports veterinary medicine by providing advanced genetic testing technology to assist in the diagnosis of cancers and infectious diseases, offering lymphocyte culture techniques used in cancer immunotherapy, and developing new functional foods that can be shared between pet owners and their pets, ensuring companion animals receive appropriate examinations and treatments. Currently, we are accepting tests from animal hospitals nationwide. Furthermore, we are developing technology to apply activated lymphocyte culture techniques to the health management of livestock (with domestic and foreign patents obtained) and have begun the development of artificial red blood cells for animals, aiming for early practical application. 【Business Activities】 ■ Contracting, research, development, and technical guidance for animal clinical testing ■ Research, development, manufacturing, and sales of veterinary diagnostic drugs ■ Research, development, manufacturing, import, and sales of veterinary pharmaceuticals, reagents, and medical instruments and tools ■ Contracting and technical guidance for cell culture, preservation, and management ■ Research commissioning and technical guidance related to animal medicine ■ Other related services *For more details, please refer to the PDF materials or feel free to contact us.

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The blood donation system in veterinary medicine is underdeveloped, making it very difficult to secure blood for transfusions at all times, especially in cases of sudden bleeding. Our company aims to apply this for emergency transfusions in animals and treatment for anemia cases, with the goal of commercialization within five years. It can be stored indoors for two years and has no blood type, ensuring safety! ★ We are looking for partners for joint development and funding! ★ 【Features】 ■ No blood type ■ No sources of infection, no concerns about infectious diseases ■ Can be stored indoors for two years ■ Blood compatibility ■ High oxygen transport capacity ■ No accumulation when administered to different animal species *For more details, please refer to the PDF materials or feel free to contact us.

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At K9 Lab Co., Ltd., we are conducting joint research with veterinary medical institutions on the basic and clinical applications of activated lymphocyte therapy (T-LAK therapy). The technology for enhancing the immunity of calves through the administration of activated lymphocytes derived from donor cows is designed to protect valuable animals from diseases through immune enhancement. Patents have been granted in Japan, Australia, New Zealand, and Canada, and are currently under examination in the USA, EU, and UAE (Japanese Patent No. 5006992). 【Expected Effects】 ■ Overall immune enhancement in calves ■ Prevention of infectious disease onset ■ Enhancement of vaccine efficacy ■ Reduction of mortality rates ■ No severe side effects (FS data) *For more details, please refer to the PDF document or feel free to contact us.

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