三和化学研究所 List of Products and Services

Do you have any concerns or requests regarding formulation? - Unable to create tablets - Want to improve stability against light - Want to create tablets that do not expose the API even when split - Want to control the timing of API dissolution - Want to reduce the contact area between APIs in combination products These concerns and requests may be resolved using OSDrC technology! If you are interested, please check the details of OSDrC technology at the link below (Sanwa Chemical Research Institute's special site on Ipros) or download the main brochure and case study materials (technical documentation) for your review. If you have any questions, please feel free to contact us. ◎●◎ Sample Presentation ◎●◎ For those who wish, we will send you tablet samples made using OSDrC technology. *: OSDrC technology refers to our unique formulation technology that allows for the production of core tablets in one step with a rotary tablet press. By supplying the inner core in powder form, we can avoid tablet pressing issues such as core misalignment that occur during conventional core tablet manufacturing, and we can also expect benefits in terms of quality assurance.

• Other medical supplies and cosmetics manufacturing machines

The "OSDrC" technology allows for precise and flexible control of the inner core due to its variable double-structure technology, enabling the production of higher quality core tablets than ever before, as well as the development of various new dosage forms. Core tablets with an extremely thin outer layer can also be manufactured in one step. This makes it possible to replace film-coated tablets, significantly compresses the manufacturing process, and reduces production costs. 【Features】 ■ Core tablets with an extremely thin outer layer can be manufactured in one step ■ Enables the replacement of film-coated tablets ■ Significant compression of the manufacturing process ■ Achieves reduction in production costs *For more details about OSDrC technology, please refer to the OSDrC main brochure available on the special website below or feel free to contact us.

• Contract manufacturing

The "OSDrC" technology, with its variable double-structure pestle, allows for precise and flexible control of the inner core, enabling the production of higher quality core tablets than ever before, as well as the development of various new dosage forms. With this technology, it is now possible to manufacture split-type core tablets in one step, which was previously impossible. For example, the "OSDrC split-type enteric tablet" is an enteric tablet that can be split. Since the inner core is always encapsulated by the outer layer, it can maintain the desired release control characteristics even when split. 【Features】 ■ Split-type core tablets can be manufactured in one step. ■ The inner core is always encapsulated by the outer layer. ■ The desired release control characteristics can be maintained. *Data demonstrating that the outer layer function is maintained even when the tablet is split, thanks to OSDrC technology, can be viewed by downloading from the special website below. *For more details about OSDrC technology, please refer to the OSDrC main brochure available on the special website below, or feel free to contact us.

• Contract manufacturing

The "OSDrC" technology allows for precise and flexible control of the inner core due to its variable double-structure pestle, enabling the production of higher quality core tablets than ever before, as well as the development of various new dosage forms. The "OSDrC" does not require a supply process for the inner core, allowing even difficult-to-form powders to be included in the inner core. In other words, it is possible to encapsulate the inner core drug in powder form with the outer layer, making it applicable to orally disintegrating tablets. If pellets are placed in the inner core, it is also possible to convert capsule formulations into tablet forms. In this way, it can significantly change the traditional formulation design process. 【Features】 ■ Does not require a supply process for the inner core ■ Can include difficult-to-form powders in the inner core ■ If pellets are placed in the inner core, it is possible to convert capsule formulations into tablets *For more details about OSDrC technology, please refer to the OSDrC main brochure on the special website below or feel free to contact us.

• Contract manufacturing

The "OSDrC" technology allows for precise and flexible control of the inner core due to its variable double-structure design, enabling the production of high-quality core tablets and facilitating the development of various new dosage forms. By utilizing accurate inner core positioning technology, it is possible to control the release start time of the active ingredients by adjusting the thickness of the outer layer. Additionally, it can accurately position multiple inner cores, making it possible to manufacture tablets with various pulse release characteristics. 【Features】 ■ The thickness of the outer layer allows for free control of drug release. ■ Accurate positioning of multiple inner cores is achievable. ■ Tablets with various pulse release characteristics can be manufactured. * Data demonstrating that the OSDrC technology can control the release start time and the number of releases of active ingredients can be viewed by downloading from the special website below. * For more details about the OSDrC technology, please refer to the OSDrC main brochure available on the special website below, or feel free to contact us.

• Contract manufacturing

The "OSDrC" technology, with its variable double-structure design, allows for precise and flexible control of the inner core, enabling the production of high-quality core tablets compared to conventional methods, as well as facilitating the development of various new dosage forms. By localizing the active ingredient in the inner core and using a highly moldable powder for the outer layer, it is possible to create tablets even from active ingredients that have poor moldability. 【Features】 ■ The increase in tablet size can be minimized even for OD tablets, which tend to have a larger powder volume. ■ The hardness and disintegration properties of the tablets can be adjusted according to the intended purpose. ■ It is possible to combine with other OSDrC technologies, such as OD tablets that do not expose the inner core when split. * Data comparing the wear resistance of OSDrC tablets produced using OSDrC technology with tablets physically mixed with active ingredients that have poor moldability can be viewed by downloading from the special website below. * For more details on OSDrC technology, please refer to the OSDrC main brochure available on the special website below or feel free to contact us.

• Contract manufacturing

The "OSDrC" technology, with its variable double-structure core, allows for precise and flexible control of the inner core, enabling the production of higher quality core tablets than ever before, as well as facilitating the development of various new dosage forms. Even active ingredients that become unstable when dispersed can be tabletized into manageable sizes while ensuring stability by localizing the active ingredients within the inner core. 【Features】 ■ Stabilization of active ingredients that become unstable when dispersed is possible ■ Reduction of cross-contamination between the inner core and outer layer is expected ■ Tablets resembling three-layer tablets can be produced by localizing powder in three locations *Data demonstrating the improved stability of active ingredients that become unstable when dispersed due to localization using OSDrC technology can be viewed by downloading from the special website below. *For more details about OSDrC technology, please refer to the OSDrC main brochure available on the special website below, or feel free to contact us.

• Contract manufacturing

The "OSDrC" technology allows for precise and flexible control of the inner core due to its variable double-structure design, enabling the production of higher quality core-containing tablets than ever before, as well as the development of various new dosage forms. By localizing the active ingredients in the inner core and physically protecting them with an outer layer, stability against light is improved. 【Features】 ■ The outer layer can be of any desired thickness. ■ It is possible to manufacture formulations that place light-sensitive active ingredients in the inner core and less light-sensitive active ingredients in the outer layer. * Data demonstrating the protective effect of active ingredients from light using OSDrC technology can be viewed by downloading from the special website below. ◎ Sample Offer ◎ For those interested, we will send samples of tablets made using OSDrC technology. Please indicate your request for samples and the quantity in the inquiry form below. *: One person's sample consists of two PTP packaged sheets (one sheet each of round tablets and oblong tablets). * For more details about OSDrC technology, please refer to the OSDrC main brochure available on the special website below, or feel free to contact us.

• Contract manufacturing

The "OSDrC" technology allows for precise and flexible control of the inner core due to its variable double-structure design, enabling the production of higher quality core tablets than ever before, as well as the development of various new dosage forms. Core tablets with an extremely thin outer layer can also be manufactured in one step. This makes it possible to replace film-coated tablets, significantly compress the manufacturing process, and reduce production costs. 【Features】 ■ Core tablets with an extremely thin outer layer can be produced in one step ■ Enables the replacement of film-coated tablets ■ Significant compression of the manufacturing process ■ Achieves reduction in production costs ◎●◎ Sample Presentation ◎●◎ We will send samples of tablets made using OSDrC technology to those who request them. Please indicate your request for samples and the quantity in the inquiry form below. *: One person's sample includes two sheets of PTP packaging (one sheet each of round and oblong tablets). * For more details about OSDrC technology, please refer to the OSDrC main brochure or feel free to contact us.

• Other contract services
• Other contract manufacturing

The "OSDrC" technology, with its variable double-structure pestle, allows for precise and flexible control of the inner core, enabling the production of higher quality core tablets than ever before, as well as the development of various new dosage forms. With this technology, it is now possible to manufacture split-type core tablets in one step, which was previously impossible. For example, the "OSDrC Split-type Enteric Tablet" is an enteric tablet that can be split. Since the inner core is always encapsulated by the outer layer, it can maintain the desired release control characteristics even when split. 【Features】 ■ Split-type core tablets can be manufactured in one step ■ The inner core is always encapsulated by the outer layer ■ The desired release control characteristics can be maintained * Data demonstrating that the outer layer function is maintained even when the tablet is split, thanks to OSDrC technology, can be viewed by downloading the PDF below. * For more details about OSDrC technology, please refer to the OSDrC main brochure or feel free to contact us.

• Pharmaceutical factory equipment

The "OSDrC" technology allows for precise and flexible control of the inner core due to its variable double-structure pestle, enabling the production of higher quality core tablets than ever before, as well as facilitating the development of various new dosage forms. Since "OSDrC" does not require a supply process for the inner core, it can incorporate even difficult-to-form powders into the inner core. In other words, it is possible to encapsulate the inner drug in powder form with the outer layer, making it applicable to orally disintegrating tablets. Additionally, by placing pellets in the inner core, it is also possible to convert capsule formulations into tablet forms. Thus, it can significantly change the traditional formulation design process. 【Features】 ■ Does not require a supply process for the inner core ■ Can incorporate even difficult-to-form powders into the inner core ■ By placing pellets in the inner core, it is possible to convert capsule formulations into tablets ◎●◎ Sample Presentation ◎●◎ We will send tablet samples made using OSDrC technology to those who request them. Please indicate your request for a sample and the quantity in the inquiry form. *For more details about OSDrC technology, please refer to the OSDrC main brochure or feel free to contact us.

• Pharmaceutical factory equipment

The "OSDrC" technology allows for precise and flexible control of the inner core due to its variable double-structure tablet design, enabling not only the production of higher quality core tablets than conventional methods but also the development of various new dosage forms. By localizing the active ingredient in the inner core and using a highly moldable powder for the outer layer, it is possible to create tablets even from active ingredients that have poor moldability. 【Features】 ■ The increase in tablet size can be minimized even for OD tablets, which tend to have a larger amount of powder. ■ The hardness and disintegration of the tablets can be adjusted according to the intended purpose. ■ It is possible to combine with other OSDrC technologies, such as OD tablets that do not expose the inner core even when split. ◎●◎ Sample Presentation ◎●◎ We will send samples made using OSDrC technology to those who request them. Please indicate the quantity in the inquiry form. * Data comparing the wear degree of OSDrC tablets made with OSDrC technology and tablets physically mixed with active ingredients that have poor moldability can be viewed by downloading the PDF below. * For more details about OSDrC technology, please refer to the OSDrC main brochure or feel free to contact us.

• Other contract services

The "OSDrC" technology, with its variable double-structured core, allows for precise and flexible control of the inner core, enabling the production of high-quality core tablets that surpass traditional methods and facilitating the development of various new dosage forms. Even active ingredients that become unstable when dispersed can be stabilized by localizing them in the inner core, allowing for tablet formulation in a manageable size while ensuring stability. 【Features】 ■ Stabilization of active ingredients that become unstable when dispersed is possible. ■ Reduction of cross-contamination between the inner core and outer layer is expected. ■ It is also possible to produce three-layer tablets that localize powder in three locations. ◎●◎Sample Presentation◎●◎ For those interested, we will send samples of tablets made using OSDrC technology. Please indicate your request for samples and the quantity in the inquiry form below. *: One person's sample consists of two sheets of PTP packaging (one sheet each of round and oblong tablets). Data demonstrating the improved stability of active ingredients that become unstable when dispersed, achieved through localization using OSDrC technology, can be viewed by downloading the PDF below.

• Other contract manufacturing

The "OSDrC" technology allows for precise and flexible control of the inner core due to its variable double-structure design, enabling the production of high-quality core tablets and facilitating the development of various new dosage forms. By utilizing accurate inner core positioning technology, it is possible to control the release start time of active ingredients by adjusting the thickness of the outer layer. Additionally, it can accurately position multiple inner cores, making it possible to manufacture tablets with various pulse release characteristics. 【Features】 ■ The thickness of the outer layer allows for free control of drug release. ■ Accurate positioning is possible even with multiple inner cores. ■ Capable of producing tablets with various pulse release characteristics. ◎●◎ Sample Presentation ◎●◎ We will send tablet samples made using OSDrC technology to those who request them. * Data demonstrating that the OSDrC technology can control the release start time and number of releases of active ingredients can be viewed by downloading the PDF below. * For more details about the OSDrC technology, please refer to the OSDrC main brochure or feel free to contact us.

• Pharmaceutical factory equipment

The "OSDrC" technology allows for precise and flexible control of the inner core due to its variable double-structure design, enabling the production of high-quality core-containing tablets and facilitating the development of various new dosage forms. By localizing the active ingredient in the inner core and physically protecting it with an outer layer, stability against light is improved. 【Features】 ■ The outer layer can be of any desired thickness. ■ It is possible to produce formulations that place light-sensitive active ingredients in the inner core while positioning light-resistant active ingredients in the outer layer. ◎ Sample Offer ◎ We will send tablet samples made using OSDrC technology to those who request them. Please indicate your request for samples and the quantity in the contact form below. *: Each request includes 2 sheets of PTP packaging for one person (one sheet each for round tablets and oblong tablets). Data demonstrating the protective effect of active ingredients from light using OSDrC technology can be viewed by downloading the PDF below.

• Other contract services