バイロクエスト List of Products and Services

The document explains "New Tools for HIV Diagnosis." It highlights that both neutralizing and non-neutralizing antibodies target gp160, which is gaining attention as a target for diagnosis and vaccines. Additionally, it presents HIV-1 and HIV-2 gp140 (SOSIP) antigens from various virus groups and subtypes. We encourage you to read it. 【Featured Products】 ■ Human immunodeficiency virus subtype A, gp140 ■ Human immunodeficiency virus subtype C, gp140 ■ Human immunodeficiency virus subtype AE, gp140 ■ Human immunodeficiency virus subtype B, gp140 ■ Human immunodeficiency virus type 2, gp140 ■ Human immunodeficiency virus clade O, gp140 *For more details, please refer to the PDF document or feel free to contact us.

• Research Antibodies
• others

The fully organic standard material "PROtrol Series" is a solution that contributes to quality control in antigen testing. By using inactivated organisms that mimic clinical samples, it efficiently demonstrates the functionality of assays and helps reduce the time and cost of retesting. It is recommended for those who require accurate and efficient antigen testing. 【Features】 ■ Biological quality control materials that provide comprehensive testing data ■ Reported specific protein concentrations and viral titers before inactivation minimize quality assurance testing ■ Available for research reagents, in vitro diagnostic products, and in vitro diagnostic products with European CE marking ■ Manufactured by the reliable ZeptoMetrix *In Japan, this is a reagent for research purposes. Please refer to the materials for more details. Feel free to contact us with any inquiries.

• Other analytical and testing equipment

We offer the highly reliable "NATtrol" brand of molecular controls/panels from ZeptoMetrix as third-party molecular diagnostic QC for infectious disease testing. These can be used across various molecular testing platforms and assays, enabling the monitoring of test performance and enhancing the quality and reliability of clinical laboratory operations. They can be used immediately after refrigeration storage, allowing for smooth workflow. 【Features】 ■ Mimics actual clinical specimens ■ Contributes to the management of extraction and amplification processes ■ Can be utilized for training testing staff ■ Allows for the evaluation of consistency between lots of testing reagent kits and assay reagents *In Japan, this is considered a reagent for research purposes. Please refer to the materials for more details. Feel free to contact us with any inquiries.

• Other analytical and testing equipment

We offer the highly reliable "NATtrol" molecular controls/panels from ZeptoMetrix as third-party molecular diagnostic QC for respiratory testing. These can be used across various molecular testing platforms and assays, allowing for the monitoring of test performance and enhancing the quality and reliability of clinical laboratory operations. They can be used immediately after refrigeration, facilitating smooth workflow. 【Features】 ■ Mimics actual clinical specimens ■ Contributes to the management of extraction and amplification processes ■ Can be utilized for training testing staff ■ Allows for the evaluation of consistency between lots of testing reagent kits and assay reagents *In Japan, this is a reagent for research purposes. Please refer to the materials for more details. Feel free to contact us with any inquiries.

• Other analytical and testing equipment

Our company provides various virus-related research reagents manufactured by ZeptoMetrix. We would like to introduce reagent kits specialized for ELISA and Western blot from our product lineup. 【Product Lineup】 ◎ 'ZeptoMetrix ELISA Reagent Kit' A prepared reagent with stability suitable for refrigeration. ■ Ideal for the detection of retrovirus antigens from various samples including cell culture media, serum, and plasma (RETROTEK ELISA Reagent Kit) ■ Efficiently detects and quantifies immunoglobulins such as IgG, IgM, and IgA from humans, mice, and other species (IMMUNOTEK ELISA Reagent Kit) ◎ 'ZeptoMetrix Western Blot Reagent Kit' A research reagent kit that enables the high-sensitivity detection of IgG antibodies in serum and plasma. ■ The Simian Immunodeficiency Virus (SIV) reagent kit consists of test strips, non-reactive and reactive controls, 20x wash buffer, conjugate, substrate, and reaction trays. ■ Our SIV and Zika virus Western blot test strips can also be used for assays customized by researchers.

• reagent

We provide various standard materials from ZeptoMetrix that assist in the development, validation, and implementation of molecular assays related to oncology. Customization is also possible to meet laboratory needs. Please utilize them for obtaining consistent and accurate results in validation, inter-lot testing, and regular quality control. 【Features】 'Human DNA Deletion Plasma' - Standard materials can be produced tailored to specific time-limited needs while retaining the natural components of the sample. - Suppresses background DNA noise in plasma. 'Cell-free DNA (cfDNA) Control' - Can be used for performance evaluation of assays detecting somatic mutations in cfDNA through PCR, next-generation sequencing (NGS), and other novel readout methods. - Contributes to ensuring the accuracy of high-sensitivity assays necessary for detecting cfDNA in plasma. *In Japan, these are reagents for research purposes. Please refer to the materials for more details. Feel free to contact us with any inquiries.

• others

The "Seroconversion Panel" manufactured by ZeptoMetrix is a product suitable for assay development, evaluation, and troubleshooting. It offers a lineup of over 160 panels for HIV, HBV, HCV, Zika, and more, providing single patient specimens continuously collected throughout the progression of diseases. Each specimen comes with analytical data for comparative analysis. 【Features】 ■ Rapid detection of antigens and antibodies ■ Composed solely of 4% sodium citrate plasma ■ Preservative-free ■ Ready to use *For more details, please refer to the materials. Feel free to contact us as well.

• others

At Biroquest Co., Ltd., we handle a wide range of specimens from healthy individuals to patients with various diseases. The formats of the specimens include serum, plasma, other bodily fluids, tissues, and FFPE, among others. For healthy individuals, we provide specimens that are negative for each viral marker using FDA-approved testing systems. All specimens are obtained with informed consent from each donor in accordance with IRB regulations. 【Features】 ■ Wide range of specimens from healthy individuals to patients with various diseases ■ FDA-approved testing systems ■ Provision of specimens that are negative for each viral marker ■ Obtained with informed consent from each donor ■ Requests for both stock items and new collections are possible *For more details, please refer to the PDF document or feel free to contact us.

• Other bio materials

All donor materials provided by ProNique have been tested and confirmed to be negative for HIV 1&2, HBsAg, HCV, syphilis, and HIV-1 antigen using FDA-approved testing methods. These products should be handled at Biosafety Level 2 as recommended in the CDC/NIH manual "Biosafety in Microbiological and Biomedical Laboratories." This product is sold only for in vitro diagnostic/research use or for further manufacturing. **Features** - Confirmed negative through testing using FDA-approved methods - Sold only for in vitro diagnostic/research use or for further manufacturing *For more details, please refer to the PDF document or feel free to contact us.*

• Other bio materials

Bairokquest Co., Ltd. provides a wide range of services to all researchers active at the forefront of life sciences. Every year, millions of people undergo infectious disease testing. Since reporting false positives or false negatives can have a significant impact on patients, accurate and highly sensitive diagnostics are necessary to ensure that laboratories provide appropriate results to patients. By consistently using external test controls and verification panels, the reliability of test results can be maximized. By routinely using the 'ZeptoMetrix NATtrol controls and panels', laboratories can monitor daily test variability, performance between lots of test kits, and the performance of individual operators, which helps identify trends in test results. Additionally, performance has been demonstrated on multiple major instrument platforms from manufacturers such as Abbott, Applied, BioCode, BD, BioFire, and Cepheid. *For more details, please refer to the PDF document or feel free to contact us.

• Other cell research

Bairokquest Inc. provides a wide range of services to all researchers active at the forefront of life sciences. Coronaviruses are common worldwide and are part of a large family of viruses that can cause diseases ranging from the common cold to Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome. We provide developers and laboratories with safe-to-use external quality control/panels for assay development or research and analytical studies. [Features] ■ NATtrol molecular controls are non-infectious, ready-to-use whole organisms designed to evaluate the performance of molecular tests. ■ Can be used for assay validation, training of testing personnel, and monitoring lot performance of assay kits. ■ Ultraviolet-inactivated virus culture media is designed for analytical testing using antigens. *For more details, please refer to the PDF materials or feel free to contact us.

• Culture water
• Other cell research

Bairokquest Co., Ltd. provides a wide range of services to all researchers active at the forefront of life sciences. Norovirus (NoV) is a small, non-enveloped, positive-sense RNA virus belonging to the Caliciviridae family. Our company offers four types of antibodies manufactured by Native Antigen. 【Product Lineup】 ■ Mouse monoclonal antibody specific for Norovirus genotype II (Clone ID6) ■ Mouse monoclonal antibody specific for Norovirus genotype II (Clone JB3) ■ Mouse monoclonal antibody specific for Norovirus genotype II (Clone ED10) ■ Anti-Norovirus VLP Polyclonal Antibody *For more details, please refer to the PDF document or feel free to contact us.

• Research Antibodies

Bairokquest Co., Ltd. provides a wide range of services to all researchers active at the forefront of life sciences. Monkeypox is one of the viral zoonotic diseases. Native Antigen Company has been working on the development of a series of antigens to support research related to this disease. In the "Native Antigen Company Monkeypox Virus Antigens and Related Antibodies," four core proteins P4A, P4B, VP8, and 39kDa protein, as well as the major envelope protein F13L, have been developed. [Product Lineup] ■ Rabbit anti-vaccinia virus polyclonal Antibody ■ Monkeypox virus VP8 / 25kDa protein, C-terminal His-tag ■ Monkeypox virus A5L gp115 / 39kDa protein, C-terminal His-tag *For more details, please refer to the PDF document or feel free to contact us.

• Research Antibodies

Bairoquest Inc. provides a wide range of services to all researchers active at the forefront of life sciences. The 'Monkeypox Virus (Recombinant) Stock' is designed to detect a specific part of the Monkeypox virus genome and aims to support the evaluation of nucleic acid tests. This product helps laboratories monitor variations in testing, performance between lots of test kits, and operator variability, aiding in the identification of random or systematic errors. 【Features】 ■ Designed to detect a specific part of the Monkeypox virus genome ■ Aims to support the evaluation of nucleic acid tests ■ Laboratories can monitor variations in testing and operator variability ■ Helps identify random or systematic errors ■ Unit size: 1mL *For more details, please refer to the PDF document or feel free to contact us.

• Other Nucleic Acid/DNA Research

Our company has partnered with NativeAntigen, which specializes in virus research, to engage in the culture and purification of virus receptors, the production of virus-like particles, and the development of bulk reagents. In addition to being compliant with ISO9001, we also meet the quality standards for raw materials of ISO13485 and GMP systems. While ensuring high quality standards, we also offer flexible custom services. 【Features】 ■ Traceable management from manufacturing to delivery, ensuring high quality and reliability ■ A wide range of flexible custom services and post-manufacturing inspections ■ Accelerating manufacturing and purification through various methods, achieving agile scaling ■ Supporting consistent research and development from basic research to drug discovery and in vitro diagnostic development *For more details, please refer to the materials. Feel free to contact us with any inquiries.

• Other research reagents

This document introduces Native Antigen's 'SARS-CoV-2'. It includes the 'SARS-CoV-2 Spike Glycoprotein (full-length), His-Tag (CHO)', as well as the 'SARS-CoV-2 Spike Glycoprotein (trimer), His-Tag (CHO)' and the 'SARS-CoV-2 Spike Glycoprotein (S1), Sheep Fc-Tag (HEK293)'. Native Antigen provides recombinant SARS-CoV-2 and related antigens and monoclonal antibodies for virus research. [Contents (excerpt)] ■ SARS-CoV-2 Spike Glycoprotein (full-length), His-Tag (CHO) ■ SARS-CoV-2 Spike Glycoprotein (trimer), His-Tag (CHO) ■ SARS-CoV-2 Spike Glycoprotein (S1), Sheep Fc-Tag (HEK293) *For more details, please refer to the PDF document or feel free to contact us.

• Other Protein Research Software
• Other cells
• Other cell research

The "NATtrol SARS-CoV2 Series" is a non-infectious, refrigerated-stable product that contains chemically modified, purified intact virus particles, manufactured by ZeptoMetrix (ZMC) for nucleic acid testing. Due to being chemically and enzymatically treated and having modifications made to the surface proteins, it can be safely used for research and development without binding to or entering host cells. 【Products Available (partial list)】 ■ NATSARS(COV2)-ERC Positive Control ■ NATSARS(COV2)-NEG Negative Control ■ Recombinant Stock ■ Reagents for Endotoxin Testing (Lysate) *For more details, please refer to the materials available for download in PDF format. Feel free to contact us with any inquiries.

• Other Nucleic Acid/DNA Research

Tempo Bioscience was established in 2013 and develops cell models and ion sensors based on human iPSCs (and related technologies). These are useful technologies for drug discovery research and development in preclinical settings, biobanking, in vitro diagnostics, and biomarker research. The company is engaged in advanced technologies focusing on disease modeling and drug safety evaluation using highly advanced human iPSC-derived cell models in both 2D and 3D. The company's cell models aim to improve efficacy and safety evaluations during drug development. 【Product Line (Excerpt)】 < Biosensors > ■ TempoVol-Rapid ■ TempoVol-iNStem ■ TempoCal-Rapid ■ TempoCal-iNStem ■ TempoCal-iAstro *For more details, please refer to the PDF document or feel free to contact us.

• Human cells
• Other cells
• Other bio-related products and services

iXCells Biotechnologies is a global research and development organization specializing in various patient-derived iPSCs and primary cells. We are capable of providing reliable, high-quality iPS cells and cell-related products and services at an affordable price with quick delivery times. We offer stem cell and primary culture cell solutions suitable for research in drug discovery, toxicity testing, disease modeling, cell therapy, and personalized medicine. 【Features】 ■ A wide range of disease-specific iPS cells available ■ Reliable, high-quality iPS cells and cell-related products and services at an affordable price with quick delivery times ■ Related services to support research activities, including diverse primary culture cells, suitable media, and 3D models *For more details, please refer to the PDF document or feel free to contact us.

• Other cell research
• Cell-related contract
• Other bio-related products and services

This document explains the "Human Coronavirus Antigens" handled by Biroquest Co., Ltd., specifically from Native Antigen. It includes detailed images of various human coronavirus antigens, starting with "Recombinant Human Angiotensin-Converting Enzyme 2 (ACE2) Extracellular Domain (18-615)." 【Contents】 ■Human ACE2 (18-615) Recombinant Protein, Fc-Tag (CHO) ■Human ACE2 (18-615) Recombinant Protein, Sheep Fc-Tag (HEK293) ■Human ACE2 (19-740) Recombinant Protein, Fc-Tag (CHO) ■Human CD147 (22-205) Recombinant Protein, Fc-Tag (CHO) ■Human Coronavirus 229E Nucleoprotein (E. coli) *For more details, please refer to the PDF document or feel free to contact us.

• Other bio-related products and services
• Other analytical and testing equipment
• others

This document introduces the "SARS-CoV-2 IgA, IgG, IgM Quantitative Measurement Kit" handled by Biroquest Co., Ltd. It includes explanations about coronaviruses in "Background I," as well as sections on "Purpose of Use" and "Contents of the Kit," presented with graphs and images. [Contents] ■ Background I ■ Background II ■ Background III ■ Nucleocapsid Protein (N) Pros and Cons ■ Spike Protein (S1) Pros and Cons *For more details, please refer to the PDF document or feel free to contact us.

• Research Antibodies
• Other research reagents
• Other analytical and testing equipment

Our company provides human tissues, body fluids, and accompanying clinical information collected in the most suitable manner for our clients' experimental designs. We offer human tissues through a global network of over 80 collaborating donor institutions, enabling excellent and optimal specimen provision. We accommodate a wide range of specimen formats, including tissues, serum, plasma, peripheral blood mononuclear cells (PBMCs), bone marrow mononuclear cells (BMMCs), urine, and sputum. Additionally, we have information on the human tissue specimen bank "XpressBANK," so please take a look at that as well. 【Features】 ■ A wide range of specimen formats ■ Provision of a broad spectrum of disease-related specimens ■ Excellent service *For more details, please refer to the catalog or feel free to contact us.

• Other contract services
• Human cells

"XpressBANK" is a human tissue specimen bank that offers various sample forms. It is used to support research in pharmaceuticals and biotechnology, providing specimens for a range of diseases and sites, particularly focusing on malignant tumors, respiratory diseases, and gastrointestinal diseases. Additionally, for all specimens, the Asterand Bioscience certified clinical pathologist committee conducts IRB approval, consent acquisition, and clinical data review to ensure the quality of the tissues, diagnoses, and specimens. Furthermore, we also offer "ProCURE," which provides human tissues, body fluids, and associated clinical information, so please feel free to contact us. [Features] - Various sample forms - Specimens for a variety of diseases and sites - Used to support research in biotechnology *For more details, please refer to the catalog or feel free to contact us.

• Human cells
• Other bio products

"SeroDetect" is a reagent manufactured by ZeptoMetrix, designed to monitor assay performance in various in vitro assay systems. It consists of a product group made from human plasma-derived components and non-human-derived components, ensuring the stability of the final product's quality by appropriately processing the raw materials and removing unnecessary components. This product should be evaluated and handled as a product containing unknown samples. 【Features】 ■ Stabilizes the quality of the final product ■ Made from human plasma-derived components and non-human-derived components ■ Designed to monitor assay performance *For more details, please refer to the catalog or feel free to contact us.

• Other research reagents
• reagent