イーベック Product Lineup

In addition to our human monoclonal antibody production service, we conduct an antibody acquisition feasibility assessment as a pre-test. Using the samples provided by our customers, we screen to determine whether antibodies against the desired target can be obtained. In this service, we evaluate the serum antibody titer against the desired antigen using serum provided simultaneously with PBMC, select three samples that are likely to yield antibodies, induce the proliferation of antibody-producing cells using the EBV method, and check the feasibility of antibody acquisition by examining the frequency of antibody-producing cells that bind to the target antigen using the culture supernatant. [Features] ■ Utilizes human peripheral blood lymphocytes owned by the customer ■ Screens for the feasibility of obtaining antibodies against the desired target *For more details, please refer to the catalog or feel free to contact us.

• Other contract services
• Other Testing Contract
• Other analysis and evaluation services

We have established a healthy human antibody library from the culture supernatants of LCL derived from antibody-producing cells (including memory B cells) using the EBV method. The library is composed of samples from 100 donors, created from mononuclear cells isolated from 100 to 200 ml of blood per person. By using human peripheral blood lymphocytes (PBMC) collected from various ethnicities around the world, we can explore the feasibility of obtaining human antibodies against specific antigens. 【Features】 ■ Composed of 100 donors ■ Created from mononuclear cells isolated from 100 to 200 ml of blood per person ■ Immediate checks can be made to determine which donors are suitable for antibody production *For more details, please refer to the catalog or feel free to contact us.

• Other contract services

We use human PBMCs (peripheral blood lymphocytes) as materials to clone the target antibody gene using the EBV method and produce fully human monoclonal antibodies. We create a library of healthy human samples consisting of over 100 specimens to assess the likelihood of obtaining the target antibody from healthy individuals. If there are specimens from which we can determine a high probability of acquiring the target antibody based on the results obtained, we can start antibody screening using our owned sample specimens. We emphasize acquiring antibodies that maintain their original activity, producing full-length heavy and light chains without converting them to scFv. 【Features】 - Application of the EBV method - Cloning of the target antibody gene and production of fully human monoclonal antibodies - Emphasis on acquiring antibodies that maintain their original activity - No scFv conversion *For more details, please refer to the catalog or feel free to contact us.

• Other cell research