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The cosmetic-grade hydroxyapatite "Apaline Series" is a skin-friendly material developed through Sangi's unique apatite technology. Through selective adsorption, it preferentially adsorbs excess sebum and old keratin from the skin's surface while protecting moisturizing ingredients and barrier functions. It is intended for use in cosmetics and quasi-drugs, compliant with the quasi-drug standards of 2021. The series is lined up according to suitable applications, and product comparisons are available for download in the catalog. 【Features】 ■ Safe mineral material ■ Excellent selective adsorption performance ■ Skin-friendly usability ■ Stable particle management and quality *For more details, please download the PDF or feel free to contact us.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients

"Hydroxyapatite for Cosmetic Ingredients" is a spherical hydroxyapatite powder manufactured using our proprietary technology, possessing characteristics suitable for cosmetic ingredients. Compared to general hydroxyapatite powders, it has excellent slip properties, superior tactile feel, good biocompatibility, and high safety, making it possible to promote skin-friendly cosmetics. By concealing the unevenness of the skin's surface, it makes fine lines and pores less noticeable, enhancing the beauty of the skin. [Features] ■ Smooth tactile feel ■ Light diffusion effect ■ Excellent oil absorption ■ Sharp particle size distribution ■ High safety *Samples are also available. If you contact us through our website, we can provide sample work along with more technical support. *For more details, please download the PDF or feel free to contact us.

• Chemicals

"Apamed" <General Purpose> is an amorphous agglomerated powder manufactured from high-purity calcium as the starting material. We offer custom-made solutions for product specifications and standard tests tailored to our customers' needs. Utilizing the excellent biocompatibility and bioaffinity of hydroxyapatite, it can be used as a raw material for medical devices. [Applications] ■ Raw materials for medical devices ■ Artificial bones ■ Dental implants ■ DDS carriers, etc. *For more details, please refer to the PDF document or feel free to contact us.

• Other polymer materials

"Apamed" <spherical> is a spherical particle manufactured from high-purity calcium. Utilizing the excellent biocompatibility and bioaffinity of hydroxyapatite, it can be used as a raw material for medical devices. Additionally, we can adjust the particle size and particle size distribution according to customer needs, and control granule strength through heat treatment, so please feel free to consult us. [Applications] ■ Raw materials for medical devices ■ Artificial bones ■ Artificial dental roots ■ Injectable implant materials ■ DDS carriers, etc. *For more details, please refer to the PDF materials or feel free to contact us.

• Other polymer materials

"Apamed" is a medical device-grade hydroxyapatite that complies with ISO 13779-6 Implants for surgery - Hydroxyapatite. This product is an amorphous agglomerated powder manufactured from high-purity calcium as the starting material. In addition to this product, we also offer spherical particle products. Please feel free to contact us when you need assistance. 【Applications】 ■ Raw materials for medical devices ■ Artificial bone ■ Artificial dental roots ■ DDS carriers, etc. *For more details, please refer to the PDF document or feel free to contact us.

• Chemicals

The cosmetic ingredient "Aparin" selectively adsorbs oxidized proteins. It can be used as a functional ingredient that not only adsorbs and removes lipid peroxides, which are said to be a cause of aging, but also prevents shine and breakdown caused by the formation of a sebum film. The special shape of the plate-like Aparin significantly increases oil absorption compared to amorphous products. It is recommended for those developing new concept cosmetics. We also offer custom-made solutions for product specifications and standard tests tailored to your needs, so please feel free to consult with us.

• Chemicals

The cosmetic ingredient "Aparin" selectively adsorbs lipid peroxides due to its specific adsorption properties with bio-organic components. This property is utilized for the adsorption and removal of oxidized proteins and the separation and purification of serum. We also offer custom-made solutions for product specifications and standard tests tailored to your needs, so please feel free to consult with us.

• Chemicals

This document introduces the origin, manufacturing, properties, uses, and application fields of hydroxyapatite, as well as a presentation of apatite products. It also explains the basic physical properties and uses of various apatite general-purpose products, including plate-shaped and spherical forms. Additionally, case studies with photographs are included. We encourage you to read it. 【Contents (partial)】 ■ What is Hydroxyapatite? - Origin of Apatite - Manufacturing of Hydroxyapatite - Properties of Hydroxyapatite - Uses and application fields of Hydroxyapatite *For more details, please refer to the PDF document or feel free to contact us.

• Chemicals

"Apasider" is a white inorganic antibacterial agent that carries metallic silver on calcium phosphate. It is composed of calcium phosphate, which is the main component of hard biological tissues such as teeth and bones. Since it does not release silver ions and has high safety, it can be used for various applications. It has a high persistence of antibacterial effect, allowing products to remain clean for a long time. 【Features】 ■ Broad antibacterial spectrum ■ Can be formulated without preservatives by replacing them with alternatives like parabens ■ High persistence of antibacterial effect, keeping products clean for a long time ■ No discoloration, fading, or odor changes, maintaining the aesthetic quality of the product ■ Minimal toxicity and skin irritation, making it suitable for a wide range of cosmetics ■ High heat resistance and stability, with no taste or odor, so it does not adversely affect formulations *For more details, please refer to the PDF document or feel free to contact us.

• Other safety and hygiene products

"Aparin" is a hydroxyapatite that meets the standards for quasi-drug ingredients. It adsorbs excess sebum secreted from the skin and suppresses shine. High cleansing effects can be achieved while maintaining moisturizing ingredients. You can utilize the excellent biocompatibility of hydroxyapatite and its unique adsorption properties for organic biological components as a cosmetic ingredient. 【Features of Selective Adsorption】 ■ Specifically adsorbs peroxidized lipids, which are a cause of skin roughness ■ Adsorbs excess sebum secreted from the skin and suppresses shine ■ High cleansing effect while maintaining moisturizing ingredients *For more details, please refer to the PDF document or feel free to contact us.

• Other polymer materials

Hydroxyapatite achieves both excess sebum adsorption and moisturizing. When sebum oxidizes, it becomes peroxidized sebum, which can lead to skin damage. Hydroxyapatite selectively adsorbs peroxidized lipids. It can be applied in a wide range of cosmetic fields, including facial cleansers, foundations, clay packs, and BB creams. 【Features】 ● Specifically adsorbs peroxidized lipids, which are a cause of skin roughness ● Adsorbs excess sebum secreted from the skin, suppressing shine ● High cleansing effect while maintaining moisturizing ingredients *For more details, please refer to the PDF materials or feel free to contact us.

• others

60% of human bones, 97% of tooth enamel, and 70% of dentin are made of "hydroxyapatite." This substance is known to have a high affinity for biological tissues as it is the main component of hard biological tissues. Additionally, it is possible to impart various properties depending on the shape of the particles. It is used in a wide range of applications, including industrial raw materials, cosmetic ingredients, food additives, and biomaterials. 【Features】 - Manufacturing methods include dry method, wet method, hydrothermal method, and spray pyrolysis method. - There are two crystal faces, the a face and the c face. - Proteins adsorb due to the charge of the crystal faces. - It has a wide range of applications as a raw material for various products. *For more details, please refer to the PDF document or feel free to contact us.

• others

"Hydroxyapatite" is a type of calcium phosphate and is known to be the main component of hard biological tissues such as bones and teeth, which gives it a high affinity for biological systems and a high level of safety. By controlling the particle shape through synthetic methods, it can possess various properties, allowing us to provide products tailored to our customers' needs. [Features] - Odorless white powder - Various types that meet industrial and quasi-drug raw material standards, including high purity products - Ability to impart various properties by controlling particle shape through synthetic methods - Stable without thermal decomposition even under high-temperature heating [Basic Knowledge (PDF) Content] We provide a document summarizing the origin of the term "apatite," the manufacturing of hydroxyapatite, its properties, and examples of applications. We hope it will be helpful for your reference. *Currently offering free samples. *For more details, please refer to the PDF document or feel free to contact us.

• Other polymer materials

"Hydroxyapatite" is a type of calcium phosphate and is known to have high biocompatibility and safety as it is the main component of hard biological tissues such as bones and teeth. By controlling the particle shape through the synthesis method, it can possess various properties, allowing us to provide products tailored to our customers' needs. [Applications] ■ Pharmaceuticals: Carriers for drug delivery systems such as anticancer agents ■ Medical devices (biomaterials): Artificial tooth roots, artificial joints, artificial bones, etc. ■ Quasi-drugs: Toothpaste, mouthwash ■ Cosmetics: Soap, cleansing cream, etc. ■ Food: Calcium supplements ■ Miscellaneous goods: Deodorants, etc. ■ Fertilizers: Phosphate fertilizers ■ Environment, construction, automotive: Exhaust gas adsorbents, wastewater treatment materials, catalysts ■ Bio, regenerative medicine, etc.: Cell culture carriers, etc. [Features] ■ Odorless white powder ■ Various types that meet industrial and quasi-drug raw material standards, including high purity products ■ Various properties can be imparted by controlling the particle shape through the synthesis method ■ Stable and does not decompose even under high-temperature heating *Currently offering free samples. *For more details, please refer to the PDF document or feel free to contact us.

• Other polymer materials

"Hydroxyapatite" is a type of calcium phosphate and is known to be the main component of hard biological tissues such as bones and teeth, which gives it a high affinity for biological systems and a high level of safety. For this reason, it is widely used in cosmetics, quasi-drugs, pharmaceuticals, and other products that are close to you. By controlling the particle shape through synthetic methods, it can possess various characteristics, allowing us to provide products tailored to our customers' needs. [Features] - Odorless white powder - Various types that meet industrial, quasi-drug raw material standards, and high purity - Ability to impart various characteristics by controlling particle shape through synthetic methods - Stable and does not decompose even under high-temperature heating *For more details, please refer to the PDF document or feel free to contact us.

• Other polymer materials

"Apasider" is an inorganic silver antibacterial agent that carries metallic silver on calcium phosphate. It does not release silver ions and is composed of ingredients listed in the pharmaceutical additive standards, making it highly safe and suitable for use in medical plastics. It significantly reduces the labor involved in disinfecting areas that are frequently touched, such as switches, door knobs, desks, and menus. The antibacterial effect of plates made by adding this product to ABS and PP resins has been confirmed by the film adhesion test method (JIS Z 2801:2010). [Features] ■ High safety ■ High heat resistance ■ Resistant to discoloration ■ High antibacterial properties and persistence even at low concentrations *For more details, please refer to the PDF document or feel free to contact us.

• Other safety and hygiene products

Apasider C is an inorganic antibacterial agent that carries silver on calcium phosphate, which is a main component of teeth and bones, making it a highly safe product. It is a simple formulation that only requires adding this product as a substitute for the preservatives you use. It has high heat resistance, is less prone to discoloration, and possesses high antibacterial properties and durability at low concentrations, making it suitable for use in cosmetics and quasi-drugs. 【Features】 ■ Simple formulation that only requires adding it as a substitute for the preservatives you use ■ Usable in cosmetics and quasi-drugs ■ High heat resistance and less prone to discoloration ■ High antibacterial properties and durability at low concentrations *For more details, please refer to the PDF materials or feel free to contact us.

• Other safety and hygiene products

"Apasider Z" is an antibacterial agent made from zinc oxide with a special coating on its particle surface. This special coating suppresses the harmful effects caused by reactive oxygen species typically associated with regular zinc oxide, while utilizing the advantages of zinc oxide. Zinc oxide has been used for a long time as baby powder and is a very safe material. Safety confirmation has been conducted through various tests such as "acute toxicity tests" and "mutagenicity tests." [Features] - Microparticle grade - Zinc oxide with a special coating on the particle surface - Suppresses the harmful effects caused by reactive oxygen species typically associated with regular zinc oxide - Very high safety *For more details, please refer to the PDF materials or feel free to contact us.

• Other safety and hygiene products

"Apasider AW" is an inorganic antibacterial agent that carries silver on calcium phosphate, represented by hydroxyapatite (Ca10(PO4)6(OH)2). It does not cause fluctuations in the physical properties of the product, nor does it result in discoloration or fading that would compromise its appearance. Calcium phosphate is a highly safe substance used in food and other applications, and it has excellent biocompatibility, making it suitable for use in dental cements and artificial bones. [Features] - General-purpose grade - Broad antibacterial spectrum - Non-toxic and non-irritating to the skin - Does not cause fluctuations in the physical properties of the product - No discoloration or fading that would compromise the product's appearance *For more details, please refer to the PDF materials or feel free to contact us.

• Other safety and hygiene products

"Apasider AW-N" is an inorganic antibacterial agent that carries silver on calcium phosphate, represented by hydroxyapatite. It does not cause discoloration, fading, or odor changes, allowing it to maintain the beauty of the product in its original state. It can be applied to a wide range of materials, including synthetic resins and paper. Additionally, safety confirmations have been conducted through various tests, such as "acute toxicity tests" and "skin irritation tests." 【Features of Apasider】 ■ Broad antibacterial spectrum ■ High durability of antibacterial action, keeping products clean for a long time ■ No discoloration, fading, or odor changes, maintaining the beauty of the product ■ Minimal skin irritation ■ High heat resistance and stability *For more details, please refer to the PDF materials or feel free to contact us.

• Other safety and hygiene products

"Apasider AK" is an inorganic antibacterial agent that carries silver on calcium phosphate, represented by hydroxyapatite (Ca10(PO4)6(OH)2) and tricalcium phosphate (Ca3(PO4)2). Calcium phosphate is a highly safe substance used in food and other applications, possessing excellent biocompatibility. It is used in dental cements, artificial bones, etc., and has the properties required for antibacterial agents. 【Features】 ■ Microparticle grade ■ Broad antibacterial spectrum ■ Non-toxic and non-irritating to the skin ■ Does not alter the physical properties of the product ■ No discoloration or fading that would impair the appearance of the product *For more details, please refer to the PDF document or feel free to contact us.

• Other safety and hygiene products

"SS-5" is an antibacterial agent made by ionically bonding silver and other metal ions to an "amino acid-based surfactant" created from the amino acid "L-glutamic acid" and natural fatty acids. When using it, it should be dispersed in water and used as a dispersion. It has high safety and can be used as an antibacterial agent for post-treatment of many fibers, including natural fibers, enabling the imparting of antibacterial properties to various processed products. [Features] - Antibacterial component is silver - Effective against MRSA - Shows antibacterial activity at low concentrations - Good working environment in factories - Compatible with a wide range of processing treatments *For more details, please refer to the PDF document or feel free to contact us.

• Disinfectant
• Other safety and hygiene products

"Apasider C" is an inorganic antibacterial agent that carries silver on calcium phosphate, represented by hydroxyapatite. Calcium phosphate, which has excellent biocompatibility, is used in dental cements and artificial bones, making it very safe and effective against a wide range of microorganisms at low concentrations. Additionally, it has heat resistance and provides stable effects over a wide temperature range, among various other features. Due to its sustained antibacterial effect, it can also be stored for long periods. 【Features】 ■ Has a broad antibacterial spectrum ■ High safety confirmed through various tests ■ Does not easily cause variations in the physical properties of the product ■ Does not cause discoloration, fading, or odor changes that would damage the product's appearance ■ Has sustained antibacterial effects 【Catalog Material Benefits】 ■ Example formulations for W/O type creams ■ Comparison of antibacterial effects between general-purpose preservatives and Apasider ■ Antibacterial effects against various bacterial species (Staphylococcus epidermidis, yeast) ■ Amount of Apasider incorporated into lotions, facial cleansers, and creams and their antibacterial effects ■ Evaluation results of the antibacterial persistence of Apasider *For more details, please refer to the catalog or feel free to contact us.

• others

"Apasider C" is an inorganic antibacterial agent that carries silver on calcium phosphate, represented by hydroxyapatite. Calcium phosphate, which has excellent biocompatibility, is used in dental cements and artificial bones, making it very safe and effective against a wide range of microorganisms at low concentrations. Additionally, it has heat resistance and maintains stable effects over a wide temperature range, among various other characteristics. Due to its sustained antibacterial effect, it can also be stored for long periods. 【Features】 ■ Has a broad antibacterial spectrum ■ High safety confirmed through various tests ■ Does not easily cause fluctuations in the physical properties of the product ■ Does not cause discoloration, fading, or odor changes that would impair the product's appearance ■ Has sustained antibacterial effects 【Catalog Material Benefits】 ■ Example formulations for W/O type creams ■ Comparison of antibacterial effects between general-purpose preservatives and Apasider ■ Antibacterial effects against various bacterial species (Staphylococcus epidermidis, yeast) ■ Amount of Apasider incorporated into lotions, facial cleansers, and creams and its antibacterial effects ■ Evaluation results of the antibacterial persistence of Apasider *For more details, please refer to the catalog or feel free to contact us.

• Disinfecting and antibacterial products