丸善製薬 List of Products and Services

This document is a technical report explaining 'Hairproze <Hawthorn>', which is expected to prevent thinning hair through the extension of the growth phase. It includes information on "shortening of the growth phase due to disruption of the hair cycle" and "product information." Additionally, it introduces various testing methods and results, including "hair growth effects (human volunteer trials)." We encourage you to read it. 【Contents (excerpt)】 ■ Shortening of the growth phase due to disruption of the hair cycle ■ Suppression of transition to the regression phase ■ Product information ■ Suppression of FGF-5 expression related to the hair cycle ■ Countermeasures for androgenetic alopecia *More detailed information on ingredients and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients

This document is a technical material explaining the 'Silver Vine (Matatabi) Fruit Extract' that can be used for external environmental damage countermeasures. It includes information on the necessity of environmental measures in daily care and product information. Additionally, it introduces various testing methods and results, including the "Comparison Test of SCCP Decomposition Promotion Effects." We encourage you to read it. 【Features】 ■ Necessity of environmental measures in daily care ■ Product information ■ Suppression of SCCP generation induced by vehicle exhaust ■ Suppression of carbonylation induced by blue light (BL) ■ Comparison test of SCCP decomposition promotion effects *More detailed raw material information and consumer survey results are available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials
• Other pharmaceutical intermediates and cosmetic ingredients

Maruzen Pharmaceutical Co., Ltd. handles a variety of flower-derived extracts that beautifully enhance cosmetics. This document is a technical material regarding "Arnica Flower Extract." It includes research data on "product information," "anti-aging care," "anti-inflammatory," "whitening," "antioxidant," and more. [Features] ■ Bright yellow flowers that stand out in high mountains ■ Confirmed complex effects on anti-aging care and whitening ■ Product information ■ Anti-aging care (inhibition of human neutrophil elastase activity) ■ Whitening (suppression of melanin production) *More detailed ingredient information and useful consumer survey results are available on Maruzen Pharmaceutical's official website. Please check the link below for more information.

• Cosmetic materials and raw materials
• Food/beverage functional materials
• Other pharmaceutical intermediates and cosmetic ingredients

Maruzen Pharmaceutical Co., Ltd. offers a wide range of flower-derived extracts sourced from flower fields around the world, which beautifully enhance cosmetics. This document contains technical information regarding "Cornflower Flower Extract." It includes research data on topics such as "Product Information," "Promotion of Hyaluronic Acid Production in the Dermis," "Antioxidant," and "Promotion of Hyaluronic Acid Production in the Epidermis." [Contents] ■ The symbol of "Healing," the clear blue "Cornflower Blue" ■ Product Information ■ Promotion of Hyaluronic Acid Production in the Dermis ■ Promotion of Hyaluronic Acid Production in the Epidermis ■ Antioxidant (Reactive Oxygen Species Scavenging) *More detailed ingredient information and consumer survey results are available on Maruzen Pharmaceutical's official website. Please check the link below for more information.

• Cosmetic materials and raw materials
• Food/beverage functional materials
• Other pharmaceutical intermediates and cosmetic ingredients

This document is a technical report that explains the oil-soluble licorice extract (kanzo flavonoids) 'HG', focusing on flavonoids. It includes various testing methods and results, such as "product information" and "combination with whitening active ingredients." We encourage you to read it. 【Contents (excerpt)】 ■ Whitening ingredients derived from licorice ■ Product information ■ Whitening anti-tyrosinase/melanin production inhibition ■ Combination with whitening active ingredients ■ Other effects *More detailed information about the raw materials and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials
• Other bioproduct raw materials

This document is a technical material explaining the component Glycyrrhizin Dipotassium (GK2), which enhances water solubility by adding potassium to glycyrrhizin. It includes various testing methods and results, such as "stability information" and "suppression of NGF mRNA expression induced by SP." Please take a moment to read it. 【Features】 ■ Active ingredient derived from licorice ■ Product information ■ Anti-inflammatory - the most important approach in skincare ■ Anti-inflammatory: suppression of UV-induced PGE2 production ■ Anti-inflammatory/anti-allergic: inhibition of hyaluronidase activity *More detailed raw material information and helpful consumer survey results are available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials
• Other bioproduct raw materials

This document is a technical report explaining 'Plantage <Wrinkle>', which combines complex functionality with a sense of luxury and appeal in terms of image, incorporating five herbal ingredients derived from traditional medicine. It includes results such as "the effects of five types of Japanese and Chinese herbal extracts" and "human volunteer trials." We encourage you to read it. 【Contents】 ■ Thoroughly enhancing protective and generative power ■ Product information ■ Human volunteer trials ■ Pursuing effectiveness: the effects of five types of Japanese and Chinese herbal extracts ■ Recommended items * More detailed ingredient information and consumer survey results are available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials

This document is a technical report explaining 'Plantage <White> EX', which uses five types of Japanese and Chinese herbal extracts. It includes various testing methods and results, starting with "What is total whitening?" and covering topics such as "suppression of melanin production." Please take a moment to read it. 【Contents】 ■ Product Information ■ Suppression of Melanin Production ■ Effect on Suppressing Pigmentation ■ Suppression of Melanin Transfer ■ Suppression of Melanin Production Signals ■ Promotion of Epidermal Turnover *More detailed information about ingredients and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials

This document is a technical material explaining "Waism <Uji Tea>." It clearly presents information on topics such as "reactive oxygen species scavenging action" and "suppression of UV-induced erythema" using diagrams and photographs. Please take a moment to read it. 【Features】 ■ Premium green tea "Uji Tea" – its 800-year history ■ Product information ■ Calpain activity inhibition (prevention of delayed damage) ■ Reactive oxygen species scavenging action (prevention of immediate damage) ■ Suppression of UV-induced erythema (human volunteer tests) ■ Other effects ■ Recommended products *More detailed information on ingredients and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials

This document is a technical report explaining 'Waism <Ume>', which uses Nanko plums from Wakayama Prefecture. It includes topics such as "What is 'glycation' that accelerates skin aging?" and "Results of human volunteer trials." Please take a moment to read it. 【Contents】 ■ Spring Messenger - The end of winter and the arrival of spring ■ Product Information ■ Human Volunteer Trials ■ Other Effects ■ Recommended Products *More detailed information about the ingredients and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials

This document is a technical material that explains Yamanashi Prefecture's peach leaf extract. It studies the damage pathways caused by chlorine (i.e., low concentration) that may be encountered in real life. Furthermore, the chlorine damage reduction effect of Yamanashi peach leaf extract BG30 has been demonstrated through in vitro tests and a unique human trial involving subjects who visit the pool more than twice a week. 【Features】 ■ Exercise, beauty, and "chlorine" ■ Product information ■ Improvement in hair and skin condition of subjects who regularly visit the pool more than twice a week ■ Suppression of corneal protein carbonylation due to low concentration chlorine ■ Residual chlorine removal effect ■ Recovery of decreased expression of keratinization-related genes due to low concentration chlorine *More detailed ingredient information and useful consumer survey results are available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials

"Marjoram extract" is a raw material extracted from the leaves of marjoram. This extract has been confirmed to promote the production of type 17 collagen, which plays a role in hair growth and maintaining dark hair. Additionally, it is expected to promote the production of hyaluronic acid from within the scalp, which tends to become dry and hard, leading to a hydrated and soft scalp environment. [Features] - Promotes the expression of 17-type collagen α1 mRNA - Promotes the production of 17-type collagen - Reduces the proliferation of hair matrix cells due to male hormones - Decreases the expression of hair growth factors due to a reduction in female hormones - Promotes the production of epidermal hyaluronic acid *More detailed information about the raw materials and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials

"Plantage Moist" is a formulation that combines three types of extracts: wild thyme extract, otaneninjin extract, and marjoram extract, which work synergistically to enhance the skin's moisture retention. It increases NMF, boosts surface moisture, and enhances the skin's internal hydration with hyaluronic acid. Additionally, it is expected to have a preventive effect against incomplete keratinization, making it possible to prevent roughness in the stratum corneum. 【Features】 ■ Increases stratum corneum moisture content and NMF (amino acid) levels ■ Promotes the expression of caspase-14 mRNA ■ Promotes the production of filaggrin ■ Promotes the production of epidermal hyaluronic acid *More detailed information about the ingredients and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials

"Tokyiekisu" is a raw material that promotes cathepsin activity and enhances the decomposition of melanosomes. It promotes the activity of cathepsin, an enzyme involved in the breakdown of melanosomes, and decomposes the structure of melanosomes that have excessively accumulated deep within spots. This is expected to provide an approach to persistent spots by changing the distribution of melanin within cells. 【Features】 ■ Dispersed whitening through enhanced cathepsin activity ■ Promotion of cathepsin mRNA expression ■ Promotion of cathepsin K activity ■ Promotion of melanosome decomposition and visual effects ■ Improvement effect on spots *More detailed information about the raw material and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials

The "Fruit Wrinkle Protect Essence" gently approaches old keratin with fruit-derived organic acids, working on the quantity and quality of keratinocytes and promoting metabolism. It preemptively prevents melanin production and helps maintain skin brightness. Additionally, it is expected to be effective against recurring "adult acne" due to its ability to enhance the skin's inherent antibacterial properties. 【Features】 ■ Complex of 7 types of fruit-derived ingredients ■ Promotes the proliferation of epidermal keratinocytes ■ Promotes the production of CE strengthening factors ■ Suppresses the expression of melanocyte activation factor mRNA ■ Promotes the expression of human β-defensin 3 mRNA *More detailed ingredient information and consumer survey results are available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials

"Ten'nin Ka fruit extract" is a raw material that enhances DNA repair capabilities and extends the duration of repair activity. It works in conjunction with the DNA damage repair functions (control) that cells inherently possess, further enhancing their repair power and extending the repair activity duration, which is expected to bring a "difference" in repair results. [Features] - Enhances DNA repair capabilities and extends activity duration - Promotes DNA polymerase activity - Suppresses DNA fragmentation caused by ultraviolet rays - Suppresses cell death caused by ultraviolet rays - Antioxidant effect *More detailed information about the raw material and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

• Cosmetic materials and raw materials