ジェノメンブレン List of Products and Services

"CacoReady" is a ready-to-use product for permeability testing, delivered with CACO-2 cells seeded in a Transwell plate. It is shipped directly from ReadyCell, a Spanish company that holds the patent for the shipping medium (which is gel-like during transport). 【Features】 ■ The testing date is the week following delivery (Wednesday or Thursday), with a usage period of 5 days (Monday to Friday testing) ■ 1 to 3 media exchanges are required depending on the testing date ■ No complicated 21-day culture is needed for CACO-2 cells ■ Options for 24 and 96 well plates are available based on the intended use ■ The 24 well plate comes in three types, allowing selection based on the intended use *For more details, please refer to the PDF document or feel free to contact us.

• Other cell research
• Other cells

"ABC Transporter Vesicles Products" are products that have been highly purified using our unique technology from membrane fractions of Sf9 cells that express ABC Transporters in large quantities through a baculovirus expression system. They can be used as a simple in vitro screening system for substrates and inhibitors of ABC Transporters using a 96-well plate. They are useful for examining the pharmacokinetics, toxicity, and drug interactions of candidate compounds. 【Product Lineup】 ■ ATPase Assay - MDR1 (Human), Mdr1a, Mdr1b (Mouse) - MRP1 (Human, Rat, Dog) - MRP2 (Human, Rat, Dog, Monkey, Mouse), etc. ■ Vesicular Transport Assay - MDR1 (Human), Mdr1a, Mdr1b (Mouse) - MRP1 (Human, Rat, Dog) - MRP2 (Human, Rat, Dog, Monkey, Mouse), etc. *For more details, please refer to the PDF document or feel free to contact us.

• Other cell research
• Other cells

"TRANSiPORT Cells" are transiently expressed cells of genomic membranes. We provide HEK293 cells that have been transiently overexpressed with SLC Transporters and cryopreserved. With shipping and next-day delivery, thawing & seeding, media exchange, and assay processes, transporter tests can be conducted within two days. [Features] - HEK293 cells that have been transiently overexpressed with SLC transporters and cryopreserved - Flexible experimental planning with cryopreserved cells - Comparable activity to our stable expression cells - Approximately one week from order to delivery (shipped frozen with dry ice) - Transporter tests can be conducted within two days *For more details, please refer to the PDF document or feel free to contact us.

• Other cell research
• Other cells

The "Transporter Cultured Cell Plate" is a "disposable type" product in which HEK293 or LLC-PK1 cells expressing transporter genes are seeded onto a plate, and it comes with the reagents needed for testing. Since the necessary reagents and culture media for the tests are included, you can use it immediately after delivery. 【Features】 ■ A product with cells that stably express transporters seeded onto a plate ■ A convenient "disposable type" that can be used as is after delivery *For more details, please refer to the PDF document or feel free to contact us.

• Other cell research
• Other cells

Our company specializes in the research and development of drug transporters. To efficiently evaluate the pharmacokinetic properties of candidate compounds in drug development in vitro, we have developed various measurement systems utilizing drug transporters, and we manufacture and sell a variety of reagent kits as well as conduct contract transporter testing. Additionally, through collaboration with overseas companies, we have introduced research reagents related to pharmacokinetics and in vitro bile excretion measurement technologies, contributing to pharmacokinetic research. 【Business Activities】 ■ Development, manufacturing, and sales of transporter-expressing membranes and vesicles ■ Development, manufacturing, and sales of transporter-expressing cells ■ Supply of frozen liver cells ■ Development, manufacturing, and sales of bile excretion measurement kits ■ Development, manufacturing, and sales of various testing reagents and materials ■ Various patent licensing services ■ Conducting various contract tests *For more details, please refer to the PDF document or feel free to contact us.

• Other cell research
• Other cells

"TransFlex" is a cell plate that can be used as is, without the need for medium exchange. MDCKII cells transiently express either uptake or efflux transporters, or both, and are delivered as live cells. 【Features】 ■ Testing can be conducted the day after delivery (Thursday delivery, Friday testing) with an optimal usage period of 1 day. ■ Substrate and inhibition tests can be performed on a single 96-well plate. ■ A model closer to in vivo conditions is achieved by simultaneously expressing two or more types of transporters. ■ Flexible layout options are available. *For more details, please download the PDF or feel free to contact us.

• Other cell research
• Other cells