新成化学 List of Products and Services

We have established a synthesis method for high-purity, high-molecular-weight polyethylene glycol (PEG) with a molecular weight ranging from 200 (PEG-4: molecular weight 194) to over 5,000. By using high-purity PEG with no molecular weight distribution, we can avoid variations in evaluation data caused by subtle differences in chain length, achieving highly reproducible and reliable evaluation results. 【Features of Hydrophilic Linkers (Polyethylene Glycol: PEG)】 ■ Low non-specific adsorption: low toxicity, stealth properties ■ Improved water solubility, also soluble in organic solvents ■ High stability: stable in acids, alkalis, and in vivo ■ High-purity products with no molecular weight distribution: stable evaluation results *For more details, please download the PDF or contact us.

• Other polymer materials

We have synthesized a macrocyclic polyether using our unique high-purity long-chain polyethylene glycol synthesis technology. Currently, the largest has a repeating unit of 112 (336-Crown-112: molecular weight 4,934). The synthesis method has been established, so even larger macrocyclic structures are possible. 【Overview】 ■ Specializing in custom synthesis ■ Capable of synthesizing new compounds as well *For more details, please download the PDF or contact us.

• Other polymer materials

Our company has a long-standing track record in solution preparation, including the weighing and aliquoting of reagents, as well as the ampule aliquoting of solutions. We also respond to various requests such as gas solution adjustments, solution adjustments for water-sensitive compounds, and solution stability testing. We can help solve issues such as "wanting to eliminate the risks associated with handling hazardous materials" and "reducing costs for equipment maintenance and staff." 【About the preparation of mixed solutions】 ■ Preparation of mixed solutions containing 2 to several hundred types of compounds (from 1 ppm solutions to 1,000 ppm solutions) ■ Capable of preparing aqueous solvents and various organic solvents ■ Prepared solutions can also be delivered in ampules *For more details, please download the PDF or contact us.

• Other contract services

We handle high-purity PEG linkers. They offer good reproducibility and are easy to purify. Additionally, we can identify and optimize linker lengths suitable for evaluation systems. (General PEGs have a molecular weight distribution, so they are mixtures of oligomers.) 【Product Lineup】 ■ Hydroxyl groups ■ Amines ■ Carboxylic acids ■ Thiols ■ Azides, etc. We can also accommodate various terminal functional groups beyond those listed above. *For more details, please download the PDF or contact us.

• Other polymer materials

We synthesize various liquid crystalline compounds and various mesogenic groups that serve as building blocks for liquid crystalline compounds. Additionally, we establish synthetic routes for compounds whose synthesis methods are unknown. Please feel free to contact us if you have any requests. 【Compounds with synthesis experience】 ■Compound No. 1703 　・Cas_No 2444-19-1　(4-Hydroxyphenyl) benzoate ■Compound No. 1705 　・Cas_No 89100-59-4　(4-Hydroxyphenyl) 4-fluorobenzoate ■Compound No. 1707　 　・Cas_No --　(4-Hydroxyphenyl) 3,4-difluorobenzoate, etc. *For more details, please download the PDF or contact us.

• Other polymer materials

Our company has established a unique technology for the synthesis of single-structure polyethylene glycol (PEG) without molecular weight distribution, successfully synthesizing single molecules with a molecular weight exceeding 5,000. We are seeking collaborative research institutions to evaluate high-purity PEG. Please feel free to contact us if you are interested. 【Themes for Collaborative Research】 ■ Evaluation systems where significant differences can be expected compared to typical PEG products with molecular weight distribution ■ Research on applications that can be realized for the first time using high-purity PEG ■ Themes aimed at creating new functional substances utilizing the characteristics of PEG *For more details, please download the PDF or contact us.

• Organic Natural Materials

Our company has handled the custom synthesis of numerous cyclodextrin derivatives to date. Applying the synthesis and purification technology of these cyclodextrin derivatives, we offer a variety of cyclodextrin derivatives. 【Compounds】 ■NH2-α-CD CAS No.29556-37-4 ■NH2-β-CD CAS No.29390-67-8 ■NH2-γ-CD CAS No.118275-08-4 ■N3-α-CD CAS No.33057-59-9 ■N3-β-CD CAS No.98169-85-8 ■N3-γ-CD CAS No.120424-80-8 ■OTs-α-CD CAS No.32860-56-3 ■OTs-β-CD CAS No.67217-55-4 ■OTs-γ-CD CAS No.97227-33-3 *For more details, please download the PDF or contact us.

• Organic Natural Materials

Our company has successfully established a synthetic method that can provide the substance '13 and 9-Oxo-Octadecadienoic Acid,' one of the unsaturated fatty acids found in tomatoes, more efficiently than extraction from tomatoes. We have also established a synthesis method for the 13-Oxo and 9-Oxo-ODA isomers, and they are now available for supply. Please feel free to use them for research and development or as analytical standards. [Overview] - Single peak products can be supplied in amounts of up to approximately 10 mg. - Mixed solutions at your specified concentration can also be provided. *For more details, please download the PDF or contact us.

• Organic Natural Materials

At Shinsei Chemical Co., Ltd., we conduct custom synthesis of organic compounds and contract research using synthetic methods. We would like to introduce some examples of how we solve our customers' problems. While the synthesis methods are limited to those that can be accommodated by our equipment based on customer requests, if there is a synthesis paper for the compound, we can obtain the target substance with a probability of over 99% (based on past performance). If you would like technical materials, please click the inquiry button. 【Examples (Partial)】 ■Concerns - Unsure of the synthesis method - Need for ultra-high purity products - Request for proposals on synthesizable structures ■Solutions - Free investigation by our company for unknown synthesis methods - Proficient in HPLC purification, recrystallization, and column purification If there are no stability issues, we can reliably provide products with over 99% purity in about 100mg within a short period - Propose structures that can be synthesized at a low cost from candidates obtained through simulation *For more details, please refer to the PDF materials or feel free to contact us.

• Contract Analysis
• Contract Inspection

Shinsei Chemical Co., Ltd. has extensive experience and a proven track record in contract organic synthesis spanning 35 years. We actively respond to the synthesis of new compounds and compounds with unknown synthesis methods. Here are some examples of our custom synthesis. Please let us consult with you to approach a contract that is as cost-effective and timely as possible to your satisfaction. If you would like technical materials, please click the inquiry button. 【Examples (partial)】 ■ Synthesis examples: Known synthesis method of diamines and carboxylic acids in one step, targeting a yield of 3 mg - Case 1: Reaction with commercially available diamines - Case 2: Reaction with our product diamine (SCHEM01417) - Case 3: Purchase of 3 mg of our product diamine (SCHEM01417) and amide bond formation with carboxylic acid by the customer themselves *For more details, please refer to the PDF materials or feel free to contact us.

• Contract Analysis
• Contract Inspection

**[Specialized Technologies and Fields]** Our company specializes in custom synthesis of fine chemicals on a small scale, specifically under 100 mg. From our extensive experience in custom synthesis, we propose a range of versatile reagents and useful compounds as building blocks that we have established. Currently, we are focusing on the following themes and are capable of synthesizing various derivatives beyond the listed items. ■ Synthesis of Polyethylene Glycol (PEG) derivatives and linkers https://schem.jp/PEGList.html ■ Cyclodextrin derivatives https://schem.jp/cd.html ■ Host-guest compounds https://schem.jp/hg.html We also excel in the following compounds: ■ Stable isotope compounds ■ Non-natural amino acids ■ Dealkylation and re-alkylation technology for tertiary amines ■ ODA (13-Oxo-Octadienoic acid) and related compounds *For more details, please visit the following page* https://schem.jp/TOPcompound.html *Or contact us through the inquiry form.* https://schem.jp/inquiry_j1.html

• Chemicals
• Other contract services
• Contract Inspection