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  3. アズフレイヤ Medical Institute for Translational Health Sciense
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アズフレイヤ Medical Institute for Translational Health Sciense

addressTokyo/Koto-ku/Mitsui Link Lab Shin-Kiba 1, 413, 2-3-8 Shin-Kiba
phone03-6457-0777
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last updated:Oct 29, 2024
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エクソソーム一覧┃化粧品原料 エクソソーム一覧┃化粧品原料
INCI取得済み 化粧品原料 INCI取得済み 化粧品原料
化粧品原料 ドラゴンフルーツエクソソーム 化粧品原料 ドラゴンフルーツエクソソーム
化粧品原料 トゥルシーエクソソーム 化粧品原料 トゥルシーエクソソーム
化粧品原料 ドラゴンフルーツエクソソーム 化粧品原料 ドラゴンフルーツエクソソーム
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Cordyceps Exosomes "EXO CORD AZ"

Announcement of the completion of INCI registration for winter worm summer grass exosome cosmetic ingredients!

We would like to introduce "EXO CORD AZ," the winter mushroom summer grass exosome handled by Azufureiya Co., Ltd. Our company has completed the INCI registration for winter mushroom summer grass exosome cosmetic ingredients and has begun sales. Please feel free to contact us when you need assistance. 【Specifications】 ■Product Name: EXO CORD AZ ■INCI: Cordyceps Sinensis Extracellular Vesicles/Water ■Display Name: Winter Mushroom Summer Grass Extracellular Vesicles (tentative) *For more details, please refer to the related links or feel free to contact us.

  • Cosmetic materials and raw materials

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Purple Chrysanthemum Exosome "EXO PCM AZ"

Announcement of the completion of INCI registration for purple chrysanthemum exosome cosmetic ingredients!

We would like to introduce the Chrysanthemum Exosome, "EXO PCM AZ," handled by Azufureiya Co., Ltd. Our company has completed the INCI registration for the Chrysanthemum Exosome cosmetic ingredient and has started sales. Please feel free to contact us when you need assistance. 【Specifications】 ■Product Name: EXO PCM AZ ■INCI: Chrysanthemum Morifolium Flower Vesicles/Water ■Display Name: Chrysanthemum Flower Vesicles *For more details, please refer to the related links or feel free to contact us.

  • Cosmetic materials and raw materials

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INCI-acquired "Equine Umbilical Cord-Derived Exosomes"

Application of equine umbilical cord-derived exosomes as cosmetic ingredients! The benefits of domestically produced thoroughbred-derived exosomes.

Exosomes are small capsules with a diameter of 50 to 100 nm that are secreted by cells. They are rich in signaling molecules such as RNA and proteins, playing an important role in intercellular communication. "Equine umbilical-derived exosomes" are tiny particles secreted from stem cells obtained from the umbilical cord of horses, and they are attracting attention in the beauty field as components aimed at skin regeneration and anti-aging. The exosome particles derived from the umbilical cord are exceptionally rich, and horses are noted for having a relatively low risk of allergens, making them highly regarded for safety among animal-derived components. 【Main Expected Effects】 ✓ High moisturizing power due to abundant hyaluronic acid, ceramide, and chondroitin sulfate ✓ Support for the functions of collagen and elastin components ✓ Promotion of proliferation of dermal papilla cells ✓ Support for nutrient supply and cell division in hair follicle stem cells ✓ Improved nutrient supply to hair roots, enhancing hair growth effects < For detailed ingredient information and application examples, please download the catalog from the link below. >

  • Cosmetic materials and raw materials

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Eliminate skin and hair concerns with plant-derived exosomes! Two trending cosmetic ingredients.

Plant-derived ingredients that provide broad support for beautiful skin, anti-aging, and hair growth. Based on research data, they offer multifunctionality and contribute to the differentiation of cosmetics in development.

Exosomes are small capsules with a diameter of 50 to 100 nm that are secreted by cells. They are rich in signaling substances such as RNA and proteins, which help maintain the health of the skin and scalp. The two types of plant-derived exosome materials introduced here can broadly approach beauty, anti-aging, and hair growth by leveraging their respective characteristics. 【Dragon Fruit Exosome】 Suppresses UV rays and aging signals Reduces skin yellowness and creates a brighter tone Promotes collagen and elastin synthesis for improved firmness and elasticity Improves fine lines and sagging, strengthens the skin barrier 【Tulsi Exosome】 High concentration with antioxidant and anti-inflammatory effects Reduces redness, itching, and swelling Enhances skin barrier and moisture retention for healthier skin Supports scalp care and hair growth, improves resistance to environmental stress Both can be incorporated into skincare, hair care, and makeup products, contributing to differentiation and multifunctionality in product development. < For detailed ingredient information and application examples, please download the materials from the link below. >

  • OEM

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Start of handling plant-derived and new cosmetic ingredients.

Completed INCI registration for a new cosmetic ingredient derived from exosomes! Contributing to the realization of longevity.

We have started handling the plant-derived, novel cosmetic ingredients "EXO DRF AZ" and "EXO DRFC AZ." Our exosome cosmetic novel ingredients are suitable for incorporation into skincare products, hair care products, and makeup products. With beauty-enhancing effects and high anti-aging care based on advanced science, we will contribute to the realization of longevity for your mind and body. 【Features】 ■ Advantages: Ingredients that maximize the power of nature without using chemical synthetics ■ High safety: Since they use plant-derived components, they can be safely used even by those with sensitive skin ■ Effective beauty effects: Expected to strengthen the skin's barrier function, enhance moisturizing power, and provide a sense of transparency *For more details, please download the PDF or feel free to contact us.

  • Cosmetic materials and raw materials

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【Explanatory Material】What are Exosomes?

A document that clearly explains "exosomes," which are attracting attention as cosmetic ingredients, from the perspective of an expert in exosome research and development.

"Exosomes" are extracellular vesicles of about 100nm that are secreted by various cells in animals and plants. Our company aims to utilize the diverse range of exosomes found in many living organisms to achieve disease prevention and pre-disease care through advanced science-based health solutions, deeply approaching health and beauty. Additionally, through exosome research, we manufacture and sell pharmaceuticals, cosmetics, health foods, and cosmetic ingredients, supporting regenerative medicine-related initiatives. [Our Strengths] ■ Exosome research and development ■ Patent applications ■ Development of exosome-rich products ■ Collaboration with related companies in nucleic acid medicine ■ Development of exosome-rich cosmetics *For more details, please download the PDF or feel free to contact us.

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Proposal for hair growth serum containing exosomes for cosmetics OEM/ODM.

Our company, which owns a lab specialized in exosomes and also conducts contract analysis, offers exosome-infused cosmetics that only we can provide! We support product development.

We would like to introduce our proposed exosome-infused hair growth serum and lotion as "cosmetic OEM/ODM." Utilizing research results and technology related to exosomes, we carefully select high-quality raw materials and encapsulate them in nano-capsules. Our hair growth serum is manufactured in a lab specialized in exosomes and is a high-quality hair growth lotion created with cutting-edge technology. By encapsulating exosomes in nano-capsules, the ingredients deeply penetrate the hair dermal papilla cells, effectively supporting the prevention of hair loss and promoting hair growth. It is suitable for both men and women suffering from age-related thinning hair and hair loss, allowing for safe use. Additionally, we conduct contract analysis, giving us confidence in the quality and effectiveness of our products. We offer OEM services, and please feel free to contact us for detailed pricing and lot information. *For more details, you can download the PDF to view the brochure and actual product images.

  • OEM
  • ODM
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Soy milk fermented liquid exosome

The number of exosome particles is 616 million per ml! It helps to improve the skin environment of aging generations.

To efficiently apply as a cosmetic, soy milk and lactic acid bacteria have come together, resulting in the birth of the highly permeable beauty essence "Soy Milk Ferment Exosome." Soy isoflavones are gaining attention as materials for cosmetics and health foods because they work similarly to "female hormones," which play a significant role in maintaining femininity. The exosome ingredients, known for their high moisturizing properties and ability to nurture skin-friendly bacteria, help improve the skin environment for the aging generation. 【Specifications】 ■ Product Name: EXO SOM AZ ■ Display Name: Soy Milk Ferment Liquid ■ INC Name: Soymilk Ferment Filtrate *For more details, please refer to the related links or feel free to contact us.

  • OEM

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CBD exosome

Safety and high quality in compliance with pharmaceutical regulations! The particle count is 1.7 billion per gram.

"CBD exosomes" are expected to have effects such as anti-inflammatory, anti-acne, and antioxidant properties; however, there are serious concerns regarding their raw materials, which may be contaminated with THC, heavy metals, pesticides, and radiation. Our company verifies various particle systems and particle counts of CBD exosomes through unique research, selecting safe and top-quality CBD raw materials from around the world. We are concentrating and processing CBD exosomes into raw materials. 【Expected Effects (Partial)】 ■ Anti-inflammatory ■ Anti-acne ■ Antioxidant ■ Improves skin texture ■ Anti-aging *For more details, please refer to the related links or feel free to contact us.

  • OEM

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Amami Island thistle exosome

Suppressing the accumulation of fat in the liver (fatty liver), which is a cause of non-alcoholic liver disease, and inhibiting liver damage markers AST and ALT.

"Amami Island Thistle Exosome" is a super vegetable with a polyphenol content several times higher than that of typical superfoods, which improves liver function, and chlorogenic acid possesses strong antioxidant power. The expression of fatty acid synthesis enzyme genes in the liver and adipose tissue decreases, suppressing the ability to produce fat. Additionally, it lowers the concentration of free fatty acids in the blood, reducing the influx of fat to the liver. 【High Functionality】 ■ Suppression of liver damage markers ■ Inhibition of fatty acid synthesis enzyme gene expression ■ Reduction of free fatty acid concentration in the blood *For more details, please refer to the related links or feel free to contact us.

  • OEM

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Akagaukurua exosome

It has been known as a tonic for a long time and is attracting attention from those who tire easily and those with diminished physical strength!

"Aka Gaukura Exosome" is expected to have various effects, including improving blood flow, recovering from fatigue, anti-stress effects, and anti-inflammatory effects. It has various functions such as enhancing physical strength, anti-inflammatory effects, and anti-stress effects, and is believed to be effective against immunity, aging, and cognitive function as it influences blood flow in various organs and cells, and research is ongoing. Additionally, Aka Gaukura is excellent in improving blood flow and is expected to have a positive impact on related symptoms. [Features] ■ Blood flow improvement ■ Brain function improvement *For more details, please refer to the related links or feel free to contact us.

  • OEM

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Tulsi Exosome

Antioxidant and anti-inflammatory properties can be expected to help maintain various aspects of youthful skin!

"Turmeric exosomes" are known as adaptogens with no side effects, possessing many pharmacological effects and are referred to as the "queen of herbs," with an overwhelming number of exosome particles. They are expected to improve skin pigmentation and promote collagen synthesis, among other effects, thanks to their antioxidant and anti-inflammatory properties, helping to maintain various aspects of skin youthfulness. They help maintain normal secretion levels of the stress hormone "cortisol," enhance immune function, improve various signs and symptoms, and balance the mind, brain, and body. [Features] - No side effects - Increases resistance to various stresses - Regulates physiological functions *For more details, please refer to the related links or feel free to contact us.

  • OEM

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Rice Fermented Liquid Extract Exosome

"Exosomes" command brightening! Approximately 23.6 billion exist per 1ml.

"Rice Fermentation Liquid Extract Exosome" provides moisture, transparency, and elasticity from deep within the skin due to its whitening effects and high penetration power. It has been clarified that rice fermentation liquid promotes the production of Type 1 collagen and elastin. It is said to have high antioxidant properties that protect the skin from UV rays and suppress the occurrence of spots and freckles, making it suitable for whitening cosmetics. Additionally, the abundant amino acids, which are the main components of NMF, enhance moisturizing effects. 【Features】 ■ Enhances whitening effects ■ Provides moisture, transparency, and elasticity ■ Leads to bright, firm skin with improved barrier function *For more details, please refer to the related links or feel free to contact us.

  • OEM

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[INCI Obtained] Cosmetic Ingredient 'Dragon Fruit Exosome'

It has the effect of suppressing melanin production and inducing the expression of elastin and collagen! It is expected to brighten the skin, suppress and reduce spots, and improve sagging.

Exosomes are extracellular vesicles (EVs) of about 100 nm in size secreted by cells of plants and animals. Their surface structure is covered by a lipid bilayer, and they contain substances such as nucleic acids (microRNA, messenger RNA, DNA, etc.) and proteins. In particular, the miRNA contained in exosomes is used for intercellular information exchange. "Dragon Fruit Exosome" emits a bluish light when exposed to sunlight or UV light, producing blue light, which is the complementary color to yellow, thereby reducing the yellow tone of the skin. It has an immediate effect, and when used as a skincare ingredient, it instantly reduces skin yellowness, making the skin appear one tone brighter and more beautiful. [Effects] - Anti-aging effects on aging cells - Promotion of collagen and elastin synthesis - Skin beautifying effects - Strengthening of the skin barrier - Anti-wrinkle effects - Defense against oxidative stress *For more details, please refer to the related links or feel free to contact us.

  • OEM

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Cosmetics Manufacturing and OEM Services

We will assist you in turning your dreams into reality, from product planning to research, development, and arranging packaging and containers.

Our company responds to requests regarding cosmetic manufacturing and OEM. The exosome materials we use are derived from the research of Takahiro Ochiai, a top leader in exosome research, and we only utilize highly accurate exosomes that have undergone various studies and tests. Additionally, to maximize the use of exosomes, we propose the highest quality materials and technology. 【What are exosomes】 Exosomes are extracellular vesicles secreted by various cells, containing nucleic acids such as miRNA and mRNA, as well as proteins and lipids. They play a crucial role in the mechanisms of the onset and progression of many diseases by transferring their contents between cells through exosomes circulating in the body. *For more details, please download the PDF or feel free to contact us.

  • OEM

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