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  3. アズフレイヤ Medical Institute for Translational Health Sciense
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アズフレイヤ Medical Institute for Translational Health Sciense

addressTokyo/Koto-ku/Mitsui Link Lab Shin-Kiba 1, 413, 2-3-8 Shin-Kiba
phone03-6457-0777
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last updated:Oct 29, 2024
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エクソソーム一覧┃化粧品原料 エクソソーム一覧┃化粧品原料
INCI取得済み 化粧品原料 INCI取得済み 化粧品原料
化粧品原料 ドラゴンフルーツエクソソーム 化粧品原料 ドラゴンフルーツエクソソーム
化粧品原料 トゥルシーエクソソーム 化粧品原料 トゥルシーエクソソーム
化粧品原料 ドラゴンフルーツエクソソーム 化粧品原料 ドラゴンフルーツエクソソーム
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Exosome extract of rice fermentation liquid for raw material suppliers

Exosomes support brightening. Approximately 2.36 billion per 1ml.

For raw material suppliers, the selection of cosmetic ingredients is a crucial factor in ensuring product quality and differentiation. Ingredients with whitening effects and high permeability are essential for enhancing competitiveness in the market. Rice fermentation liquid extract exosomes provide moisture, clarity, and elasticity from deep within the skin, delivering the effects required in whitening cosmetics. 【Usage Scenarios】 - Whitening cosmetics - Anti-aging cosmetics - Moisturizing cosmetics 【Benefits of Introduction】 - Increased product added value - Improved customer satisfaction - Market differentiation

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Exosome extract of fermented rice liquid for research institutions

Exosomes command brightening! Approximately 23.6 billion exist per 1ml.

In research institutions, the analysis of exosomes from cosmetic ingredients requires the identification of their active components and the elucidation of their mechanisms of action. In particular, the analysis of the structure and components of exosomes that influence skin permeability and efficacy is a crucial factor that affects the quality of research. Our rice fermentation extract exosomes are expected to provide moisture, transparency, and elasticity from deep within the skin due to their whitening effects and high permeability. It has also been clarified that they promote the production of Type 1 collagen and elastin, expanding new possibilities for research. 【Application Scenarios】 - Structural analysis of exosomes - Identification of active components - Elucidation of mechanisms of action - Research on whitening effects 【Effects of Introduction】 - Promotion of research on skin effects - Acquisition of new insights in cosmetic development - Contribution to paper publication and patent acquisition

  • OEM

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[For OEM Manufacturers] Rice Fermented Liquid Extract Exosomes

"Exosomes" command brightening! Approximately 23.6 billion exist per 1ml.

For OEM manufacturers, selecting ingredients for cosmetics that differentiate products and meet customer needs is crucial. Ingredients that achieve both whitening effects and gentleness on the skin are essential for enhancing product value in a highly competitive market. Our "Rice Fermented Liquid Extract Exosome" offers whitening effects, high penetration, and moisturizing properties, contributing to the improvement of OEM product quality. 【Usage Scenarios】 - Whitening cosmetics - Anti-aging cosmetics - Moisturizing cosmetics 【Benefits of Implementation】 - Product differentiation - Increased customer satisfaction - Enhanced brand image

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Rice Fermentation Liquid Extract Exosome for Beauty

Exosomes lead to hydrated and radiant skin.

In the beauty industry, moisturizing is a crucial factor that influences customer satisfaction. To prevent skin troubles such as dryness and rough skin, and to maintain healthy skin, the incorporation of effective moisturizing ingredients is essential. Rice fermentation liquid extract exosomes provide high moisturizing power and whitening effects, contributing to brand differentiation. 【Usage Scenarios】 - Development of skincare products containing moisturizing ingredients - Incorporation into anti-aging products - Incorporation into whitening care products 【Effects of Implementation】 - Provides moisture, transparency, and elasticity from deep within the skin - Improves barrier function, resulting in bright and firm skin - Increases customer satisfaction through whitening effects

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[For Cosmetic Manufacturers] Rice Fermentation Liquid Extract Exosomes

"Exosomes" command brightening! Whitening cosmetic ingredients.

We believe that cosmetic manufacturers are looking for highly effective whitening cosmetic ingredients. In the current whitening market, there is an increasing demand for products that not only prevent spots and freckles but also provide skin transparency, moisture, and firmness simultaneously. Selecting effective ingredients is a crucial challenge for differentiating your products. Our 'Rice Fermentation Liquid Extract Exosome' offers whitening effects, high penetration, and moisturizing properties, addressing these challenges. 【Usage Scenarios】 - Whitening cosmetics - Brightening care products - Anti-aging care products 【Benefits of Introduction】 - Increased product value through whitening effects - Providing moisture, transparency, and elasticity from deep within the skin - Supporting barrier function for brighter and firmer skin

  • OEM

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INCI acquisition of plant-derived ingredient 'Dragon Fruit Callus Exosome'

Cosmetic ingredients that suppress damage and aging signals caused by ultraviolet rays. They are expected to provide a wide range of anti-aging effects, including beautiful skin, suppression of spots, and improvement of sagging.

Exosomes are small capsules with a diameter of 50 to 100 nm that are secreted by cells. They are rich in signaling molecules such as RNA and proteins, playing an important role in intercellular communication. Callus refers to a mass of undifferentiated cells formed in plants at damaged areas or under specific environmental conditions, possessing high regenerative ability and differentiating into various tissues and organs. "Dragon Fruit Callus Exosome" is a plant-derived cosmetic ingredient that suppresses UV rays and aging signals. It is expected to have skin beautifying effects that reduce yellowness and instantly create a brighter skin tone. 【Expected Effects】 ✓ Anti-aging: Approaches aging cells ✓ Promotes collagen and elastin synthesis: Supports skin firmness and elasticity ✓ Skin beautifying effects and skin barrier enhancement: Leads to healthy and even skin ✓ Anti-wrinkle effects: Contributes to the improvement of fine lines and sagging ✓ Oxidative stress defense: Protects the skin from UV rays and environmental stress By incorporating it into skincare products, immediate skin brightening and aging care can be achieved. Its multifunctionality based on the latest research also contributes to differentiation in product development. < For detailed ingredient information and application examples, please download the materials from the link below. >

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Dragon Fruit Exosomes for Personal Care

Supports skin firmness and elasticity for healthy skin.

In the personal care industry, especially in moisturizing products, it is important to protect the skin from dryness and external stimuli while maintaining hydration. Strengthening the skin's barrier function and maintaining healthy skin is essential. Dragon fruit exosomes are ideal for incorporation into moisturizing products as they support skin firmness and elasticity, leading to healthier skin. 【Usage Scenarios】 - Moisturizing cream - Body lotion - Serum 【Effects of Introduction】 - Retention of skin moisture - Strengthening of skin barrier function - Support for skin firmness and elasticity

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Wellness Dragon Fruit Exosomes

Supports health from the inside with antioxidant effects.

In the wellness industry, there is a growing demand for products aimed at maintaining health and enhancing immunity. Oxidative stress in the body caused by reactive oxygen species can lead to a decline in immune function, making antioxidant ingredients highly valued. Dragon fruit exosomes are ideal for inclusion in supplements aimed at supporting immunity due to their antioxidant properties. 【Usage Scenarios】 - Immune support supplements - Health maintenance supplements 【Benefits of Introduction】 - Health maintenance through antioxidant effects - Support for immune function - Differentiated product development

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Beauty-oriented Dragon Fruit Exosomes

Supports beautiful skin from within with antioxidant effects.

In the beauty industry, the demand for skin beautification effects is increasing. In particular, the impact of UV rays and environmental stress on the skin is a concern for many people. There is a need for effective measures against issues such as decreased skin firmness and elasticity, as well as dullness. Dragon fruit exosomes, with their antioxidant properties, are ideal ingredients for inclusion in skin beautification care products to address these challenges. 【Usage Scenarios】 - Skin beautifying supplements - Anti-aging products - Care for skin firmness and elasticity 【Effects of Introduction】 - Defense against skin oxidative stress - Promotion of collagen and elastin synthesis - Healthier and more even skin - Anti-aging effects

  • OEM

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Dragon Fruit Exosomes for Supplements

Supplement ingredients that support health from within with antioxidant effects.

In the supplement industry, there is a growing demand for ingredients with antioxidant properties, driven by consumers' increasing health consciousness. In particular, oxidative stress in the body caused by reactive oxygen species is a significant factor in aging and various health issues, making countermeasures important. Dragon fruit exosomes are ideal for incorporation into supplements as an ingredient with antioxidant properties. 【Usage Scenarios】 - Antioxidant supplements - Anti-aging care supplements - Health maintenance supplements 【Benefits of Introduction】 - Health maintenance through antioxidant effects - Anti-aging effects - Differentiated product development Our company contributes to your health and beauty through exosome research. We aim to achieve disease prevention and pre-disease care through advanced science-based healthcare, such as exosomes. Please feel free to contact us if you have any inquiries.

  • OEM

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Cordyceps Exosomes "EXO CORD AZ"

Announcement of the completion of INCI registration for winter worm summer grass exosome cosmetic ingredients!

We would like to introduce "EXO CORD AZ," the winter mushroom summer grass exosome handled by Azufureiya Co., Ltd. Our company has completed the INCI registration for winter mushroom summer grass exosome cosmetic ingredients and has begun sales. Please feel free to contact us when you need assistance. 【Specifications】 ■Product Name: EXO CORD AZ ■INCI: Cordyceps Sinensis Extracellular Vesicles/Water ■Display Name: Winter Mushroom Summer Grass Extracellular Vesicles (tentative) *For more details, please refer to the related links or feel free to contact us.

  • Cosmetic materials and raw materials

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Purple Chrysanthemum Exosome "EXO PCM AZ"

Announcement of the completion of INCI registration for purple chrysanthemum exosome cosmetic ingredients!

We would like to introduce the Chrysanthemum Exosome, "EXO PCM AZ," handled by Azufureiya Co., Ltd. Our company has completed the INCI registration for the Chrysanthemum Exosome cosmetic ingredient and has started sales. Please feel free to contact us when you need assistance. 【Specifications】 ■Product Name: EXO PCM AZ ■INCI: Chrysanthemum Morifolium Flower Vesicles/Water ■Display Name: Chrysanthemum Flower Vesicles *For more details, please refer to the related links or feel free to contact us.

  • Cosmetic materials and raw materials

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INCI-acquired "Equine Umbilical Cord-Derived Exosomes"

Application of equine umbilical cord-derived exosomes as cosmetic ingredients! The benefits of domestically produced thoroughbred-derived exosomes.

Exosomes are small capsules with a diameter of 50 to 100 nm that are secreted by cells. They are rich in signaling molecules such as RNA and proteins, playing an important role in intercellular communication. "Equine umbilical-derived exosomes" are tiny particles secreted from stem cells obtained from the umbilical cord of horses, and they are attracting attention in the beauty field as components aimed at skin regeneration and anti-aging. The exosome particles derived from the umbilical cord are exceptionally rich, and horses are noted for having a relatively low risk of allergens, making them highly regarded for safety among animal-derived components. 【Main Expected Effects】 ✓ High moisturizing power due to abundant hyaluronic acid, ceramide, and chondroitin sulfate ✓ Support for the functions of collagen and elastin components ✓ Promotion of proliferation of dermal papilla cells ✓ Support for nutrient supply and cell division in hair follicle stem cells ✓ Improved nutrient supply to hair roots, enhancing hair growth effects < For detailed ingredient information and application examples, please download the catalog from the link below. >

  • Cosmetic materials and raw materials

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Eliminate skin and hair concerns with plant-derived exosomes! Two trending cosmetic ingredients.

Plant-derived ingredients that provide broad support for beautiful skin, anti-aging, and hair growth. Based on research data, they offer multifunctionality and contribute to the differentiation of cosmetics in development.

Exosomes are small capsules with a diameter of 50 to 100 nm that are secreted by cells. They are rich in signaling substances such as RNA and proteins, which help maintain the health of the skin and scalp. The two types of plant-derived exosome materials introduced here can broadly approach beauty, anti-aging, and hair growth by leveraging their respective characteristics. 【Dragon Fruit Exosome】 Suppresses UV rays and aging signals Reduces skin yellowness and creates a brighter tone Promotes collagen and elastin synthesis for improved firmness and elasticity Improves fine lines and sagging, strengthens the skin barrier 【Tulsi Exosome】 High concentration with antioxidant and anti-inflammatory effects Reduces redness, itching, and swelling Enhances skin barrier and moisture retention for healthier skin Supports scalp care and hair growth, improves resistance to environmental stress Both can be incorporated into skincare, hair care, and makeup products, contributing to differentiation and multifunctionality in product development. < For detailed ingredient information and application examples, please download the materials from the link below. >

  • OEM

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Start of handling plant-derived and new cosmetic ingredients.

Completed INCI registration for a new cosmetic ingredient derived from exosomes! Contributing to the realization of longevity.

We have started handling the plant-derived, novel cosmetic ingredients "EXO DRF AZ" and "EXO DRFC AZ." Our exosome cosmetic novel ingredients are suitable for incorporation into skincare products, hair care products, and makeup products. With beauty-enhancing effects and high anti-aging care based on advanced science, we will contribute to the realization of longevity for your mind and body. 【Features】 ■ Advantages: Ingredients that maximize the power of nature without using chemical synthetics ■ High safety: Since they use plant-derived components, they can be safely used even by those with sensitive skin ■ Effective beauty effects: Expected to strengthen the skin's barrier function, enhance moisturizing power, and provide a sense of transparency *For more details, please download the PDF or feel free to contact us.

  • Cosmetic materials and raw materials

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【Explanatory Material】What are Exosomes?

A document that clearly explains "exosomes," which are attracting attention as cosmetic ingredients, from the perspective of an expert in exosome research and development.

"Exosomes" are extracellular vesicles of about 100nm that are secreted by various cells in animals and plants. Our company aims to utilize the diverse range of exosomes found in many living organisms to achieve disease prevention and pre-disease care through advanced science-based health solutions, deeply approaching health and beauty. Additionally, through exosome research, we manufacture and sell pharmaceuticals, cosmetics, health foods, and cosmetic ingredients, supporting regenerative medicine-related initiatives. [Our Strengths] ■ Exosome research and development ■ Patent applications ■ Development of exosome-rich products ■ Collaboration with related companies in nucleic acid medicine ■ Development of exosome-rich cosmetics *For more details, please download the PDF or feel free to contact us.

  • Other cell research

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Proposal for hair growth serum containing exosomes for cosmetics OEM/ODM.

Our company, which owns a lab specialized in exosomes and also conducts contract analysis, offers exosome-infused cosmetics that only we can provide! We support product development.

We would like to introduce our proposed exosome-infused hair growth serum and lotion as "cosmetic OEM/ODM." Utilizing research results and technology related to exosomes, we carefully select high-quality raw materials and encapsulate them in nano-capsules. Our hair growth serum is manufactured in a lab specialized in exosomes and is a high-quality hair growth lotion created with cutting-edge technology. By encapsulating exosomes in nano-capsules, the ingredients deeply penetrate the hair dermal papilla cells, effectively supporting the prevention of hair loss and promoting hair growth. It is suitable for both men and women suffering from age-related thinning hair and hair loss, allowing for safe use. Additionally, we conduct contract analysis, giving us confidence in the quality and effectiveness of our products. We offer OEM services, and please feel free to contact us for detailed pricing and lot information. *For more details, you can download the PDF to view the brochure and actual product images.

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Soy milk fermented liquid exosome

The number of exosome particles is 616 million per ml! It helps to improve the skin environment of aging generations.

To efficiently apply as a cosmetic, soy milk and lactic acid bacteria have come together, resulting in the birth of the highly permeable beauty essence "Soy Milk Ferment Exosome." Soy isoflavones are gaining attention as materials for cosmetics and health foods because they work similarly to "female hormones," which play a significant role in maintaining femininity. The exosome ingredients, known for their high moisturizing properties and ability to nurture skin-friendly bacteria, help improve the skin environment for the aging generation. 【Specifications】 ■ Product Name: EXO SOM AZ ■ Display Name: Soy Milk Ferment Liquid ■ INC Name: Soymilk Ferment Filtrate *For more details, please refer to the related links or feel free to contact us.

  • OEM

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CBD exosome

Safety and high quality in compliance with pharmaceutical regulations! The particle count is 1.7 billion per gram.

"CBD exosomes" are expected to have effects such as anti-inflammatory, anti-acne, and antioxidant properties; however, there are serious concerns regarding their raw materials, which may be contaminated with THC, heavy metals, pesticides, and radiation. Our company verifies various particle systems and particle counts of CBD exosomes through unique research, selecting safe and top-quality CBD raw materials from around the world. We are concentrating and processing CBD exosomes into raw materials. 【Expected Effects (Partial)】 ■ Anti-inflammatory ■ Anti-acne ■ Antioxidant ■ Improves skin texture ■ Anti-aging *For more details, please refer to the related links or feel free to contact us.

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Amami Island thistle exosome

Suppressing the accumulation of fat in the liver (fatty liver), which is a cause of non-alcoholic liver disease, and inhibiting liver damage markers AST and ALT.

"Amami Island Thistle Exosome" is a super vegetable with a polyphenol content several times higher than that of typical superfoods, which improves liver function, and chlorogenic acid possesses strong antioxidant power. The expression of fatty acid synthesis enzyme genes in the liver and adipose tissue decreases, suppressing the ability to produce fat. Additionally, it lowers the concentration of free fatty acids in the blood, reducing the influx of fat to the liver. 【High Functionality】 ■ Suppression of liver damage markers ■ Inhibition of fatty acid synthesis enzyme gene expression ■ Reduction of free fatty acid concentration in the blood *For more details, please refer to the related links or feel free to contact us.

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Akagaukurua exosome

It has been known as a tonic for a long time and is attracting attention from those who tire easily and those with diminished physical strength!

"Aka Gaukura Exosome" is expected to have various effects, including improving blood flow, recovering from fatigue, anti-stress effects, and anti-inflammatory effects. It has various functions such as enhancing physical strength, anti-inflammatory effects, and anti-stress effects, and is believed to be effective against immunity, aging, and cognitive function as it influences blood flow in various organs and cells, and research is ongoing. Additionally, Aka Gaukura is excellent in improving blood flow and is expected to have a positive impact on related symptoms. [Features] ■ Blood flow improvement ■ Brain function improvement *For more details, please refer to the related links or feel free to contact us.

  • OEM

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Tulsi Exosome

Antioxidant and anti-inflammatory properties can be expected to help maintain various aspects of youthful skin!

"Turmeric exosomes" are known as adaptogens with no side effects, possessing many pharmacological effects and are referred to as the "queen of herbs," with an overwhelming number of exosome particles. They are expected to improve skin pigmentation and promote collagen synthesis, among other effects, thanks to their antioxidant and anti-inflammatory properties, helping to maintain various aspects of skin youthfulness. They help maintain normal secretion levels of the stress hormone "cortisol," enhance immune function, improve various signs and symptoms, and balance the mind, brain, and body. [Features] - No side effects - Increases resistance to various stresses - Regulates physiological functions *For more details, please refer to the related links or feel free to contact us.

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Rice Fermented Liquid Extract Exosome

"Exosomes" command brightening! Approximately 23.6 billion exist per 1ml.

"Rice Fermentation Liquid Extract Exosome" provides moisture, transparency, and elasticity from deep within the skin due to its whitening effects and high penetration power. It has been clarified that rice fermentation liquid promotes the production of Type 1 collagen and elastin. It is said to have high antioxidant properties that protect the skin from UV rays and suppress the occurrence of spots and freckles, making it suitable for whitening cosmetics. Additionally, the abundant amino acids, which are the main components of NMF, enhance moisturizing effects. 【Features】 ■ Enhances whitening effects ■ Provides moisture, transparency, and elasticity ■ Leads to bright, firm skin with improved barrier function *For more details, please refer to the related links or feel free to contact us.

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[INCI Obtained] Cosmetic Ingredient 'Dragon Fruit Exosome'

It has the effect of suppressing melanin production and inducing the expression of elastin and collagen! It is expected to brighten the skin, suppress and reduce spots, and improve sagging.

Exosomes are extracellular vesicles (EVs) of about 100 nm in size secreted by cells of plants and animals. Their surface structure is covered by a lipid bilayer, and they contain substances such as nucleic acids (microRNA, messenger RNA, DNA, etc.) and proteins. In particular, the miRNA contained in exosomes is used for intercellular information exchange. "Dragon Fruit Exosome" emits a bluish light when exposed to sunlight or UV light, producing blue light, which is the complementary color to yellow, thereby reducing the yellow tone of the skin. It has an immediate effect, and when used as a skincare ingredient, it instantly reduces skin yellowness, making the skin appear one tone brighter and more beautiful. [Effects] - Anti-aging effects on aging cells - Promotion of collagen and elastin synthesis - Skin beautifying effects - Strengthening of the skin barrier - Anti-wrinkle effects - Defense against oxidative stress *For more details, please refer to the related links or feel free to contact us.

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Cosmetics Manufacturing and OEM Services

We will assist you in turning your dreams into reality, from product planning to research, development, and arranging packaging and containers.

Our company responds to requests regarding cosmetic manufacturing and OEM. The exosome materials we use are derived from the research of Takahiro Ochiai, a top leader in exosome research, and we only utilize highly accurate exosomes that have undergone various studies and tests. Additionally, to maximize the use of exosomes, we propose the highest quality materials and technology. 【What are exosomes】 Exosomes are extracellular vesicles secreted by various cells, containing nucleic acids such as miRNA and mRNA, as well as proteins and lipids. They play a crucial role in the mechanisms of the onset and progression of many diseases by transferring their contents between cells through exosomes circulating in the body. *For more details, please download the PDF or feel free to contact us.

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