Cysay List of Products and Services

In September 2023, our company president had a discussion with Tomoko Morimoto, a former TV Tokyo announcer and currently the representative of Wellness Me Inc. We would like to share the details of that conversation (approximately 30 minutes long). The topics included, "Why did we decide to include Cysay factors in cosmetic ingredients?" and "The journey of our company and stem cell culture," among many other rich contents. Please take a look. *For more details, please refer to the PDF document or feel free to contact us.*

• Other Culture

Immortalized human dental pulp stem cell conditioned culture medium (cosmetic ingredient) can also be included in scalp care cosmetics. Aiming for a healthy scalp condition and thicker, longer, resilient, and shiny hair. We accept raw material supply and OEM/ODM orders. Evidence of hair growth effects is available. Studies conducted using keratinocytes and dermal papilla cells. ■ Keratinocyte proliferation ■ Dermal papilla cell proliferation Results from in vitro experiments conducted by our in-house research laboratory. *For more details, please refer to the PDF document or feel free to contact us.

• Cosmetic materials and raw materials

Cysay Co., Ltd. supplies cultured supernatants that can be blended as food ingredients. The application for food uses "immortalized porcine dental pulp stem cell purified culture medium." We hold patents for mammalian stem cell culture supernatants both domestically and internationally, making the cultured supernatants that can be incorporated into food a unique ingredient that only Cysay can provide. Since we culture immortalized porcine dental pulp stem cells, we consistently provide uniform and stable cultured supernatants. Food labeling can include terms such as "immortalized porcine dental pulp stem cell culture extract" or "immortalized porcine-derived stem cell culture extract." In addition to supplying raw materials, we also accept OEM and ODM requests. Please feel free to contact us when needed. *For more details, please refer to the PDF materials or feel free to reach out to us.*

• Cosmetic materials and raw materials

We would like to introduce our immortalized human dental pulp stem cell conditioned medium, "Cysay Factor." *Immortalized stem cells are abbreviated as ImS cells. Our immortalization technology allows stem cells to survive without aging for a semi-permanent period. By immortalizing them, we can continuously culture from the same human stem cells, ensuring uniform quality. *The food source is derived from pigs. **Features of Immortalized Human Dental Pulp Stem Cell Conditioned Medium = Cysay Factor** *Characteristics of Immortalized Dental Pulp Stem Cell Conditioned Medium* ◯ Patented both domestically and internationally ◯ 100% raw material without any dilution ◯ Due to the immortalization technology, the types and quantities of physiologically active substances such as cytokines and exosomes expressed from the same stem cells are identified, ensuring consistent quality ◯ Evidence can be obtained since the same human stem cells are immortalized ◯ Numerous evidences for beauty and hair growth (in vitro experiments conducted in our internal laboratory) ◯ Only our company can incorporate the culture supernatant into food (patented) ◯ It is also possible to process into freeze-dried powder We accept raw material supply and OEM/ODM orders. *For more details, please refer to the PDF document or feel free to contact us.*

• Cosmetic materials and raw materials

The culture supernatant of immortalized stem cells can be applied as pet products. It can be incorporated into pet snacks and supplements (in the case of food, it is the culture supernatant of immortalized porcine dental pulp stem cells), as well as products such as oils and mists for pet skin care. 【Features of Immortalized Dental Pulp Stem Cell Culture Supernatant】 ◯ Patented both domestically and internationally ◯ 100% raw material without any dilution ◯ Due to immortalization technology, the types and quantities of physiologically active substances such as cytokines and exosomes expressed from the same stem cells are identified, ensuring consistent quality ◯ Evidence can be obtained since the same human stem cells are immortalized ◯ Numerous evidences for beauty and hair growth (in vitro experiments conducted in our in-house laboratory) ◯ Only our company can incorporate the culture supernatant into food (patented) ◯ It can also be processed into freeze-dried powder In addition to supplying raw materials, we also accept OEM/ODM requests. *For more details, please refer to the PDF document or feel free to contact us.

• Cosmetic materials and raw materials

By immortalizing stem cells (patented technology), it becomes possible to keep stem cells alive semi-permanently without aging. The culture supernatant produced from the same stem cells expresses the same types and quantities of bioactive substances, ensuring no quality differences between batches. Since the quality is identified, evidence can be obtained. Additionally, it is a safe and secure culture supernatant that employs carefully selected dental pulp stem cells from specific donors. Immortalized human dental pulp stem cell-conditioned medium - Cysay factor - beauty effects: - Promotes turnover - Whitening effect - Cell protection effect - Antioxidant and anti-glycation effects - Improves wrinkles - Promotes collagen production - Promotes elastin production - Moisturizing effect... studied using fibroblasts (RT-PCR) - Anti-aging effect... studied using fibroblast models - Hair growth effect... studied using dermal papilla cells and keratinocytes *Results from in vitro experiments conducted in our internal research laboratory. We accept raw material supply and OEM/ODM requests. *For more details, please refer to the PDF document or feel free to contact us.

• Cosmetic materials and raw materials

Our immortalization technology allows stem cells to survive without aging for a semi-permanent period. We provide safe and secure materials using stem cells from the dental pulp of a carefully selected single donor's baby teeth. Since it is a culture supernatant of dental pulp stem cells, it has excellent compatibility with receptors in the oral cavity. Immortalization enables continuous cultivation from the same human stem cells, allowing us to produce a uniform quality culture supernatant. 【Features】 ■ The master cells are the same due to the immortalization technology, allowing for standardized product quality. ■ There is abundant research data and evidence, with clear foundations. ■ Patents obtained both domestically and internationally. ■ 100% culture supernatant concentrate (no dilution). ■ Safety quality tests such as virus stability tests conducted for each lot. ■ Filtered and filled. In addition to supplying raw materials, we also accept OEM and ODM orders. *For more details, please download the PDF or feel free to contact us.

• Other medical supplies and cosmetic manufacturing materials