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Biocom Systems, Inc.

addressFukuoka/Kurume-shi/1-1, Hyakunen-koen
phone0942-27-6581
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last updated:Jan 21, 2026
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Transdermal absorption simulation software 'SKIN-CAD'

It is the only transdermal absorption simulation software in Japan that has a proven track record of use in pharmaceutical companies and universities.

"SKIN-CAD" is a software for pharmacokinetic analysis of drugs in the skin and blood based on a transdermal absorption model. By inputting in vitro skin permeation data and known systemic pharmacokinetic parameters, it calculates the amount of transdermal absorption and the time course of blood concentration under clinical (in vivo) conditions. It can analyze the time course of blood concentration for systemic action drugs, the pharmacokinetics of local therapeutic drugs, and the skin permeation of active ingredients in cosmetics, depending on the purpose. 【Simulation Models】 ■ Skin permeation model (2-layer membrane or 1-layer membrane) ■ Drug dissolution matrix formulation/skin permeation model ■ Drug dispersion matrix formulation/skin permeation model ■ Formulation compartment/skin permeation model *For more details, please download the PDF or feel free to contact us.

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In vitro skin permeation test/release test

We propose and conduct "in vitro tests" that align with the client's objectives.

We conduct in vitro skin permeation tests and in vitro release tests on the active ingredients of pharmaceuticals and cosmetics. We evaluate pharmaceuticals, quasi-drugs, cosmetics, and veterinary medicines using animal skin, human skin, cultured skin, and artificial membranes. 【All Equipment and Instruments】 ■ Vertical diffusion cell ■ Horizontal diffusion cell ■ High-performance liquid chromatography (HPLC) ■ Moisture vapor transmission rate measurement device *For more details, please download the PDF or feel free to contact us.

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