Thank you for visiting the 25th Interphex Japan from July 5 (Wednesday) to July 7 (Friday) - Japan Diavalve

Easy with 90-degree operation! Prevents over-tightening and damage! We solve concerns like "I'm worried if it's securely tightened..."

The "BQL400NB model" is a rapid-opening and closing type handle diaphragm valve from BioClean. While the standard handle version requires about 5 turns of operation (for DN50), the rapid-opening and closing handle allows for a very simple operation of just 【opening and closing by 90 degrees】. The position of the handle makes it clear to see the valve's open and close status even from a distance. Additionally, it has achieved a lighter and more compact design compared to conventional products. Please try the easy operation and stable sealing performance of the 90-degree rotating lever handle. 【We solve the following problems!】 ■ The opening and closing torque is excessive. → It can be reduced, greatly contributing to labor savings. ■ I want to check the open and close status from a distance. → The handle position clearly shows the valve's open and close status even from afar. ■ The valve is damaged due to over-tightening. → Only the minimum necessary operation is required. This prevents damage and extends lifespan. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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No short pipe section and minimal dead leg! A compact design sample collection valve.

The "Bio-Clean Diaphragm Valve" is a dedicated valve for sample collection. Since it does not use a cheese fitting, there is no short pipe section, resulting in a smaller dead leg. Additionally, its compact design and lightweight construction help reduce the load on the piping. It can be widely used for introducing and discharging split flow, merging (mixing liquids), cleaning water, and sterilizing steam. 【Features】 ■ Does not use a cheese fitting ■ No short pipe section, resulting in a smaller dead leg ■ Compact installation due to the integrated structure of the main pipe and body ■ Average weight reduction of 23% compared to conventional products ■ Reduced load on piping due to lightweight design *For more details, please refer to the documentation. Feel free to contact us with any inquiries.

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No adhesion of tablets or powder particles, excellent cleaning properties!

We handle "valves exclusively for the discharge of tablets and powder granules." With a shape and structure that minimizes tablet residue, we offer a "damper" for safe tablet discharge, and a "butterfly valve" designed for lightweight construction, making installation and removal easy. The main components are made of stainless steel and have a buff-polished finish, ensuring no adhesion of tablets or powder granules and excellent cleanability. 【Features】 <Damper> - Structure that does not crush tablets when opening the damper - Equipped with a stopper at the opening and closing position to securely maintain the position <Butterfly Valve> - Lightweight design allows for easy installation and removal from containers and piping - Adopts a clamp method for quick assembly and disassembly, making cleaning easy *For more details, please refer to the PDF materials or feel free to contact us. (The English version of the catalog can be downloaded from the catalog page of the special website below.)

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An evolved version of the bio-clean diaphragm valve. The structure eliminates liquid pooling by positioning the valve shaft horizontally. A solution for dead space!

The self-draining type is a valve body that further enhances the liquid retention prevention effect of the Bio Clean diaphragm valve series. When this valve is installed on horizontal piping, it is designed to eliminate liquid retention by positioning the valve shaft horizontally. 【Specifications (excerpt)】 ■ Stainless steel body (Applicable nominal diameter (DN): 8 to 100) ■ Lined body (Applicable nominal diameter (DN): 15 to 50) ■ The surface finish classification of the body and diaphragm specifications follow standard specifications. ■ Various drive components for manual operation valves and pneumatic ON-OFF valves can be used interchangeably. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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Tanks from approximately 10L to 10,000L are acceptable! The opening and closing are done solely by the diaphragm, allowing for smooth discharge of the tank contents with almost no residue left.

【Features】 ● The structure is directly welded to the bottom of the tank, resulting in excellent stirring efficiency. ● There are no contact parts such as gland packing, stem, seat, or gasket; the opening and closing are done solely by the diaphragm, allowing for smooth discharge of the tank contents with minimal residue. Contamination caused by valve components is extremely low, and cleaning and sterilization can be easily and reliably performed. ● The applicable nominal diameters range from DN15 to 100 (4S), making it suitable for use with small containers of about 10 liters to medium tanks of about 10,000 liters. 【Specifications (Excerpt)】 ● Main body material: SUS316L ● Applicable nominal diameter (DN): 15 to 100 ● Operation method: Manual operation and pneumatic operation methods are both applicable. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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Diverting, merging, and the introduction and discharge of cleaning water and sterilizing steam are "applicable." The internal structure of the valve has no dead space, making it ideal for preventing liquid accumulation.

**Features** - It can be directly installed in the piping, is compact, and has a structure that prevents fluid residue in the valve. - It can be widely used for applications such as branching, merging (mixing liquids), introducing cleaning water, and discharging sterilization steam. **Specifications (Excerpt)** - Main body material: SUS316L - Applicable nominal diameter (DN): Standard combination of main pipe and valve: 15 to 50 (other ranges available as options) - Operation method: Both manual and pneumatic operation methods are applicable. *For more details, please refer to the catalog (P.20) or feel free to contact us. (An English version is available upon request!)*

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Manufacturing equipment for pharmaceuticals, food, semiconductors, etc.! A wide variety of sanitary specification valves available.

This document is a "comprehensive catalog" featuring sanitary specification valves suitable for manufacturing equipment in pharmaceuticals, food, semiconductors, and more. It includes the "Bio-Clean Diaphragm Valve Series," which maximizes the features of diaphragm valves, as well as sanitary butterfly valves for pharmaceutical containers. Customers can select valves tailored to their applications and the fluids they use. [Contents] ■ Bio-Clean Diaphragm Valves ■ Dead Space Countermeasure Products ■ Special Valves and Related Products ■ Sanitary Valves and Cleanroom Related Products ■ Technical Documentation *For more details, please refer to the PDF document or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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Aiming to create environmentally friendly valves... "The entire company is united in promoting the continuous reduction of environmental impact!" "ISO 14001 certification obtained!"

Japan Diavalve Co., Ltd. aims to be a sustainable company that balances environmental activities and economic activities amid the worsening global environmental issues. Recognizing the commitment to environmental conservation as one of the important pillars of its business activities, the company obtained ISO 14001 certification in 2008 and is working together as a whole company on environmental activities. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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<Title> Development of Gene Expression Control Technology through RNA Hacking In the latest presentation paper, we have utilized Abby. Associate Professor Yosuke Katsuta from Kumamoto University Graduate School of Advanced Science and Technology, Analytical Chemistry Laboratory (also co-founder of StapleBio), will be giving a presentation in an online seminar. He is working on the development of RNA hacking technology aimed at controlling gene expression by utilizing short nucleic acids named Staple to change the higher-order structure of target mRNA. He will present the latest data focusing on the results of cell experiments and animal experiments in the development of this technology. Related paper on the presentation content: Staple oligomers induce a stable RNA G-quadruplex structure for protein translation inhibition in therapeutics | Nature Biomedical Engineering

● This is a leak testing device for small electronic components that does not use fluorinated inert liquids (PFAS-free). ● There is no longer a need for unstable visual confirmation through liquid immersion testing. It adopts a quantitative testing method that allows for stable pressure leak testing. ● It is a tabletop leak testing device specifically for gross leaks, with accuracy equal to or greater than that of liquid immersion testing. ● The detectable range is approximately 1×10⁻² Pa·m³/s to 1×10⁻⁶ Pa·m³/s (varies depending on the target product). ● It is suitable for sealed structures ranging from a few millimeters to a maximum of 80 × 70 mm. Please feel free to contact us for more information!

The "Mechanical Stitching Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact on the base material. Repairs can be carried out in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

● The production time for casting prototypes can be shortened! Since model production is not required, the time needed to create prototypes, which previously took about a month, can be significantly reduced. ● Model costs can be reduced! By directly producing sand molds from 3D data, there is no need for model production costs. If changes to the model are necessary, they can be addressed by modifying the 3D data. ● Similar products with different shapes and dimensions can be prototyped simultaneously! With one molding process, different products with similar shapes or varying dimensions can be molded at the same time. This allows for the verification of multiple types in a short period.

The "Mechanical Stitch Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact to the base material. Repairs can be carried out in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.