【New product to be exhibited!】Announcement of participation in the 26th Interphex Japan exhibition.

Are you struggling with "contamination control"? We can eliminate liquid pooling and ensure that cleaning and sterilization can be carried out easily and reliably!

■NDV Dead Space Countermeasure Products These are products designed with a compact structure that eliminates dead spaces (such as pockets and liquid traps) in the valve body. They can be used as "contamination countermeasures" in pharmaceuticals, food, and bioprocesses. 【Are you facing these issues?】 ☑ Fluid enters the gaps inside the valve during fluid passage or when closing the valve... ☑ There are problems with large dead legs in the piping, such as liquid traps and steam sterilization effectiveness... ☑ You want to review complex piping layouts and eliminate fluid contamination risks... 【Features】 ● Sampling Valve Type P: - Enables fluid sampling without dead space! ● Three-Way Valve Type K: - Allows switching and mixing of flow paths with no dead space using a single body! ● Tank Bottom Valve Type T: - A valve specifically for tank bottoms that achieves high stirring efficiency and eliminates residual discharge! ● Self-Drain Type F: - A valve that further enhances the effect of preventing liquid traps! ■ This product will be exhibited at the "26th Interphex Japan." *For more details, please refer to the catalog or feel free to contact us.

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Easy with 90-degree operation! Prevents over-tightening and damage! We solve concerns like "I'm worried if it's securely tightened..."

The "BQL400NB model" is a rapid-opening and closing type handle diaphragm valve from BioClean. While the standard handle version requires about 5 turns of operation (for DN50), the rapid-opening and closing handle allows for a very simple operation of just 【opening and closing by 90 degrees】. The position of the handle makes it clear to see the valve's open and close status even from a distance. Additionally, it has achieved a lighter and more compact design compared to conventional products. Please try the easy operation and stable sealing performance of the 90-degree rotating lever handle. 【We solve the following problems!】 ■ The opening and closing torque is excessive. → It can be reduced, greatly contributing to labor savings. ■ I want to check the open and close status from a distance. → The handle position clearly shows the valve's open and close status even from afar. ■ The valve is damaged due to over-tightening. → Only the minimum necessary operation is required. This prevents damage and extends lifespan. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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An evolved version of the bio-clean diaphragm valve. The structure eliminates liquid pooling by positioning the valve shaft horizontally. A solution for dead space!

The self-draining type is a valve body that further enhances the liquid retention prevention effect of the Bio Clean diaphragm valve series. When this valve is installed on horizontal piping, it is designed to eliminate liquid retention by positioning the valve shaft horizontally. 【Specifications (excerpt)】 ■ Stainless steel body (Applicable nominal diameter (DN): 8 to 100) ■ Lined body (Applicable nominal diameter (DN): 15 to 50) ■ The surface finish classification of the body and diaphragm specifications follow standard specifications. ■ Various drive components for manual operation valves and pneumatic ON-OFF valves can be used interchangeably. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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No dead space (in pockets or liquid traps), fluid sampling is OK. Can be used widely!!

**Features** - Fluid sampling can be done without dead space (such as in pockets or liquid pools). - It can be directly mounted in the piping, is compact, and has a structure that prevents fluid retention in the valve. - In addition to sample collection, it can be widely used for branching, merging (mixing), introducing cleaning water or sterilizing steam, and discharging. **Specifications (Excerpt)** - Main body material: SUS316L - Applicable nominal diameter (DN): Standard combinations of main pipe and valve: 15 to 50 (other ranges available as options) - Operation method: Both manual and pneumatic operation methods are applicable. *For more details, please refer to the PDF document or feel free to contact us.*

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No short pipe section and minimal dead leg! A compact design sample collection valve.

The "Bio-Clean Diaphragm Valve" is a dedicated valve for sample collection. Since it does not use a cheese fitting, there is no short pipe section, resulting in a smaller dead leg. Additionally, its compact design and lightweight construction help reduce the load on the piping. It can be widely used for introducing and discharging split flow, merging (mixing liquids), cleaning water, and sterilizing steam. 【Features】 ■ Does not use a cheese fitting ■ No short pipe section, resulting in a smaller dead leg ■ Compact installation due to the integrated structure of the main pipe and body ■ Average weight reduction of 23% compared to conventional products ■ Reduced load on piping due to lightweight design *For more details, please refer to the documentation. Feel free to contact us with any inquiries.

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Diverting, merging, and the introduction and discharge of cleaning water and sterilizing steam are "applicable." The internal structure of the valve has no dead space, making it ideal for preventing liquid accumulation.

**Features** - It can be directly installed in the piping, is compact, and has a structure that prevents fluid residue in the valve. - It can be widely used for applications such as branching, merging (mixing liquids), introducing cleaning water, and discharging sterilization steam. **Specifications (Excerpt)** - Main body material: SUS316L - Applicable nominal diameter (DN): Standard combination of main pipe and valve: 15 to 50 (other ranges available as options) - Operation method: Both manual and pneumatic operation methods are applicable. *For more details, please refer to the catalog (P.20) or feel free to contact us. (An English version is available upon request!)*

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Tanks from approximately 10L to 10,000L are acceptable! The opening and closing are done solely by the diaphragm, allowing for smooth discharge of the tank contents with almost no residue left.

【Features】 ● The structure is directly welded to the bottom of the tank, resulting in excellent stirring efficiency. ● There are no contact parts such as gland packing, stem, seat, or gasket; the opening and closing are done solely by the diaphragm, allowing for smooth discharge of the tank contents with minimal residue. Contamination caused by valve components is extremely low, and cleaning and sterilization can be easily and reliably performed. ● The applicable nominal diameters range from DN15 to 100 (4S), making it suitable for use with small containers of about 10 liters to medium tanks of about 10,000 liters. 【Specifications (Excerpt)】 ● Main body material: SUS316L ● Applicable nominal diameter (DN): 15 to 100 ● Operation method: Manual operation and pneumatic operation methods are both applicable. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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It is possible to manufacture valve bodies tailored to specific applications and specifications! "Bioclean diaphragm valves that are optimal for pharmaceutical bioprocesses and more."

This product is a valve suitable for manufacturing equipment in pharmaceuticals, bioprocesses, cosmetics, food, and semiconductors. The diaphragm completely isolates the fluid from the drive mechanism, providing a highly airtight structure. It has a packless design that eliminates the gland packing area, which is often associated with a high risk of leakage in general valves, thus excelling in maintaining airtightness and preventing bacterial contamination. 【Features】 ■ Excellent airtightness ■ Structure that does not contaminate the fluid ■ Superior cleanability ■ Excellent maintainability ■ Customizable valve body to match applications and specifications *For more details, please refer to the sanitary valve catalog (pages 8-16) or feel free to contact us. (English and Chinese versions are available upon request!)

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Prevents the generation of foreign substances due to coating peeling! Air-operated ON-OFF valve made of stainless steel with excellent corrosion resistance. Compact and buff-polished for excellent cleanability.

This product is an ideal valve for manufacturing equipment in pharmaceuticals, bioprocesses, cosmetics, food, and semiconductors. The air-operated ON-OFF valve is available in the stainless steel drive model 'BPO1400N type 05S to 16S'. Since painting is not required, it prevents the occurrence of foreign substances due to peeling of the coating, and a retaining ring method is used to secure the bonnet and cylinder. With minimal unevenness and compact design, along with buff polishing, it offers excellent cleanability. 【Features】 ■ All stainless steel construction with excellent corrosion resistance ■ Exterior shape with superior cleanability ■ Significant improvement in smooth operation and durability *For more details, please refer to the catalog (P15-16) or feel free to contact us. (English and Chinese versions are available upon request!)

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【For pharmaceutical and food plants!】A butterfly valve with minimal powder and particle adhesion and excellent cleanability.

The "Sanitary Butterfly Valve for Powder and Granule Discharge" has numerous achievements in the discharge of powders and granules in pharmaceutical and food plants' containers. The main components are made of stainless steel, and the inner surface is finished with #400 buff polishing, which minimizes the adhesion of powders and granules and provides excellent cleanability. 【Features】 ■ Minimal adhesion of powders and granules, with excellent cleanability ■ Easy installation and removal for containers and piping ■ Adopts a clamp method for quick assembly and disassembly, making cleaning easy *For more details, please refer to the catalog or feel free to contact us.

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Rainproof equivalent to IP67! It has been reborn with an indicator that excels in visibility!

We would like to introduce our diaphragm valve limit switch box, the 'MDNB Series', specifically designed for air-operated drive units. The indicator of the conventional model has been changed from a rubber cap to a bright red, dedicated resin indicator, improving visibility. This is a compact product with a direct mount type that incorporates a micro switch. 【Features】 ■ Direct mount type with built-in micro switch ■ Changed the indicator from a rubber cap to a bright red, dedicated resin indicator ■ Improved visibility due to the change in cap shape *For more details, please refer to the PDF document or feel free to contact us.

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Introduction of lining products that prevent deterioration from corrosion and chemicals!

Introducing the "Lining Type Diaphragm Valve" with excellent resistance to corrosion and chemicals. It is utilized in a wide range of fields such as chemicals, environmental and water treatment, pharmaceuticals, and semiconductors. It can be applied to countermeasure against corrosive fluids, gap corrosion, and metal ion elution. 【Product Lineup (Example)】 "Model 430": Hard natural rubber lining on a base material of FC200 or FCD-S "Model 459": PFA lining on a base material of FCD-S or SCS13 "Model 460": ETFE lining on a base material of FCD-S "Model 450": Polyethylene lining on a base material of FC200 "Model 480": Porcelain lining on a base material of FCD-S *Sanitary specification diaphragm valves are also available. *For more details, please refer to the catalog or feel free to contact us.

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Introduction to porcelain lining products with excellent resistance to corrosion and chemicals.

The "480(04) type" is a diaphragm valve made of porcelain lining that excels in corrosion and chemical resistance. It does not experience the permeation of chemical liquids, which can be a concern under certain conditions with fluororesin lining or rubber lining. Additionally, it is suitable not only as a corrosion-resistant valve for strong acid fluids but also for highly permeable fluids such as hydrochloric acid and phosphorus trichloride. 【Features】 ■ Does not experience the permeation of chemical liquids, which can be a concern under certain conditions with fluororesin lining or rubber lining. ■ Suitable not only as a corrosion-resistant valve for strong acid fluids but also for highly permeable fluids such as hydrochloric acid and phosphorus trichloride. ■ Base material: FCD-S, Lining: Porcelain *For more details, please refer to the PDF materials or feel free to contact us. (We have English and Chinese versions of the catalog available upon request!)

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Aiming to create environmentally friendly valves... "The entire company is united in promoting the continuous reduction of environmental impact!" "ISO 14001 certification obtained!"

Japan Diavalve Co., Ltd. aims to be a sustainable company that balances environmental activities and economic activities amid the worsening global environmental issues. Recognizing the commitment to environmental conservation as one of the important pillars of its business activities, the company obtained ISO 14001 certification in 2008 and is working together as a whole company on environmental activities. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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The latest published paper utilized Abby. This will be an online seminar featuring Associate Professor Yosuke Katsuta from the Graduate School of Advanced Science and Technology, Kumamoto University, who is also a co-founder of StapleBio. He is working on RNA hacking technology development aimed at altering the higher-order structure of target mRNA using short nucleic acids named Staple nucleic acids, with the goal of controlling gene expression. He will present the latest data focusing on the results of cell experiments and animal experiments in the development of this technology. Related paper on the lecture content: "Staple oligomers induce a stable RNA G-quadruplex structure for protein translation inhibition in therapeutics" | Nature Biomedical Engineering

Nitto Kohki will hold the "2025 Attack Fair in Meiko" for two days from July 23 (Wednesday) to July 24 (Thursday), 2025, at the "Kowa Seminar Plaza 2F Training Room NO.12 (inside Kowa Sports Land)." The Attack Fair is an exhibition where you can actually "see, touch, and operate" Nitto Kohki's products. Additionally, there will be wonderful souvenirs for attendees and many fun activities planned. We look forward to welcoming everyone!

The "Building Maintenance Human Fair & Clean EXPO 2025," which will be held from November 19 (Wednesday) to 21 (Friday), 2025, is an annual exhibition specializing in the building maintenance field, organized by the National Building Maintenance Association and the Japan Management Association. The field reporting app "Smart Attack" is celebrating its 15th anniversary this year since its release. It has a proven track record of being used by many customers as an efficiency tool for various building maintenance tasks such as cleaning, security, and facility management! At our exhibition booth, we will present a demonstration and the latest information about the completely renewed new app "Smart Attack V3." ★★★ Points ★★★ Fully renewed version: New app "Smart Attack V3" The fully renewed version of the new app "Smart Attack" is here! You can see the latest version "Smart Attack V3," which has improved processing speed and a completely revamped design, in a demonstration. All of us at the company look forward to your visit.

Naviace Co., Ltd. will be exhibiting at the "39th Hokkaido Technology and Business Exchange Meeting" business expo held in Sapporo, Hokkaido (https://www.business-expo.jp/). Under the theme "Change Challenges into Strengths with Carbon Neutrality!!", we will showcase our environmentally friendly cardboard pallet, "Navi Pallet". <Product Features> - Lightweight and high load capacity to improve work efficiency - 100% recyclable and ideal for one-way operations - No heat treatment required, making it suitable for export - High design flexibility for adaptable solutions - Contributes to addressing the logistics 2024 problem and reducing CO₂ emissions The Navi Pallet not only supports the transition from manual loading and unloading to palletization but also contributes to achieving carbon neutrality. We will also display actual Navi Pallets that have been implemented at the venue. Please come and experience the "strength" and "lightness" for yourself. Exhibition Area: Sapporo Chamber of Commerce and Industry Manufacturing Corner

Techne Measurement Co., Ltd. will be exhibiting at the 66th Battery Discussion Conference, which will be held at Wink Aichi from November 18 (Tuesday) to November 20 (Thursday), 2025. This time, we will showcase dew point meters and low dew point calibrators for the battery industry. Please be sure to visit the Techne Measurement booth.