【New product to be exhibited!】Announcement of participation in the 26th Interphex Japan exhibition.

Are you struggling with "contamination control"? We can eliminate liquid pooling and ensure that cleaning and sterilization can be carried out easily and reliably!

■NDV Dead Space Countermeasure Products These are products designed with a compact structure that eliminates dead spaces (such as pockets and liquid traps) in the valve body. They can be used as "contamination countermeasures" in pharmaceuticals, food, and bioprocesses. 【Are you facing these issues?】 ☑ Fluid enters the gaps inside the valve during fluid passage or when closing the valve... ☑ There are problems with large dead legs in the piping, such as liquid traps and steam sterilization effectiveness... ☑ You want to review complex piping layouts and eliminate fluid contamination risks... 【Features】 ● Sampling Valve Type P: - Enables fluid sampling without dead space! ● Three-Way Valve Type K: - Allows switching and mixing of flow paths with no dead space using a single body! ● Tank Bottom Valve Type T: - A valve specifically for tank bottoms that achieves high stirring efficiency and eliminates residual discharge! ● Self-Drain Type F: - A valve that further enhances the effect of preventing liquid traps! ■ This product will be exhibited at the "26th Interphex Japan." *For more details, please refer to the catalog or feel free to contact us.

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Easy with 90-degree operation! Prevents over-tightening and damage! We solve concerns like "I'm worried if it's securely tightened..."

The "BQL400NB model" is a rapid-opening and closing type handle diaphragm valve from BioClean. While the standard handle version requires about 5 turns of operation (for DN50), the rapid-opening and closing handle allows for a very simple operation of just 【opening and closing by 90 degrees】. The position of the handle makes it clear to see the valve's open and close status even from a distance. Additionally, it has achieved a lighter and more compact design compared to conventional products. Please try the easy operation and stable sealing performance of the 90-degree rotating lever handle. 【We solve the following problems!】 ■ The opening and closing torque is excessive. → It can be reduced, greatly contributing to labor savings. ■ I want to check the open and close status from a distance. → The handle position clearly shows the valve's open and close status even from afar. ■ The valve is damaged due to over-tightening. → Only the minimum necessary operation is required. This prevents damage and extends lifespan. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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An evolved version of the bio-clean diaphragm valve. The structure eliminates liquid pooling by positioning the valve shaft horizontally. A solution for dead space!

The self-draining type is a valve body that further enhances the liquid retention prevention effect of the Bio Clean diaphragm valve series. When this valve is installed on horizontal piping, it is designed to eliminate liquid retention by positioning the valve shaft horizontally. 【Specifications (excerpt)】 ■ Stainless steel body (Applicable nominal diameter (DN): 8 to 100) ■ Lined body (Applicable nominal diameter (DN): 15 to 50) ■ The surface finish classification of the body and diaphragm specifications follow standard specifications. ■ Various drive components for manual operation valves and pneumatic ON-OFF valves can be used interchangeably. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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No dead space (in pockets or liquid traps), fluid sampling is OK. Can be used widely!!

**Features** - Fluid sampling can be done without dead space (such as in pockets or liquid pools). - It can be directly mounted in the piping, is compact, and has a structure that prevents fluid retention in the valve. - In addition to sample collection, it can be widely used for branching, merging (mixing), introducing cleaning water or sterilizing steam, and discharging. **Specifications (Excerpt)** - Main body material: SUS316L - Applicable nominal diameter (DN): Standard combinations of main pipe and valve: 15 to 50 (other ranges available as options) - Operation method: Both manual and pneumatic operation methods are applicable. *For more details, please refer to the PDF document or feel free to contact us.*

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No short pipe section and minimal dead leg! A compact design sample collection valve.

The "Bio-Clean Diaphragm Valve" is a dedicated valve for sample collection. Since it does not use a cheese fitting, there is no short pipe section, resulting in a smaller dead leg. Additionally, its compact design and lightweight construction help reduce the load on the piping. It can be widely used for introducing and discharging split flow, merging (mixing liquids), cleaning water, and sterilizing steam. 【Features】 ■ Does not use a cheese fitting ■ No short pipe section, resulting in a smaller dead leg ■ Compact installation due to the integrated structure of the main pipe and body ■ Average weight reduction of 23% compared to conventional products ■ Reduced load on piping due to lightweight design *For more details, please refer to the documentation. Feel free to contact us with any inquiries.

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Diverting, merging, and the introduction and discharge of cleaning water and sterilizing steam are "applicable." The internal structure of the valve has no dead space, making it ideal for preventing liquid accumulation.

**Features** - It can be directly installed in the piping, is compact, and has a structure that prevents fluid residue in the valve. - It can be widely used for applications such as branching, merging (mixing liquids), introducing cleaning water, and discharging sterilization steam. **Specifications (Excerpt)** - Main body material: SUS316L - Applicable nominal diameter (DN): Standard combination of main pipe and valve: 15 to 50 (other ranges available as options) - Operation method: Both manual and pneumatic operation methods are applicable. *For more details, please refer to the catalog (P.20) or feel free to contact us. (An English version is available upon request!)*

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Tanks from approximately 10L to 10,000L are acceptable! The opening and closing are done solely by the diaphragm, allowing for smooth discharge of the tank contents with almost no residue left.

【Features】 ● The structure is directly welded to the bottom of the tank, resulting in excellent stirring efficiency. ● There are no contact parts such as gland packing, stem, seat, or gasket; the opening and closing are done solely by the diaphragm, allowing for smooth discharge of the tank contents with minimal residue. Contamination caused by valve components is extremely low, and cleaning and sterilization can be easily and reliably performed. ● The applicable nominal diameters range from DN15 to 100 (4S), making it suitable for use with small containers of about 10 liters to medium tanks of about 10,000 liters. 【Specifications (Excerpt)】 ● Main body material: SUS316L ● Applicable nominal diameter (DN): 15 to 100 ● Operation method: Manual operation and pneumatic operation methods are both applicable. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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It is possible to manufacture valve bodies tailored to specific applications and specifications! "Bioclean diaphragm valves that are optimal for pharmaceutical bioprocesses and more."

This product is a valve suitable for manufacturing equipment in pharmaceuticals, bioprocesses, cosmetics, food, and semiconductors. The diaphragm completely isolates the fluid from the drive mechanism, providing a highly airtight structure. It has a packless design that eliminates the gland packing area, which is often associated with a high risk of leakage in general valves, thus excelling in maintaining airtightness and preventing bacterial contamination. 【Features】 ■ Excellent airtightness ■ Structure that does not contaminate the fluid ■ Superior cleanability ■ Excellent maintainability ■ Customizable valve body to match applications and specifications *For more details, please refer to the sanitary valve catalog (pages 8-16) or feel free to contact us. (English and Chinese versions are available upon request!)

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Prevents the generation of foreign substances due to coating peeling! Air-operated ON-OFF valve made of stainless steel with excellent corrosion resistance. Compact and buff-polished for excellent cleanability.

This product is an ideal valve for manufacturing equipment in pharmaceuticals, bioprocesses, cosmetics, food, and semiconductors. The air-operated ON-OFF valve is available in the stainless steel drive model 'BPO1400N type 05S to 16S'. Since painting is not required, it prevents the occurrence of foreign substances due to peeling of the coating, and a retaining ring method is used to secure the bonnet and cylinder. With minimal unevenness and compact design, along with buff polishing, it offers excellent cleanability. 【Features】 ■ All stainless steel construction with excellent corrosion resistance ■ Exterior shape with superior cleanability ■ Significant improvement in smooth operation and durability *For more details, please refer to the catalog (P15-16) or feel free to contact us. (English and Chinese versions are available upon request!)

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【For pharmaceutical and food plants!】A butterfly valve with minimal powder and particle adhesion and excellent cleanability.

The "Sanitary Butterfly Valve for Powder and Granule Discharge" has numerous achievements in the discharge of powders and granules in pharmaceutical and food plants' containers. The main components are made of stainless steel, and the inner surface is finished with #400 buff polishing, which minimizes the adhesion of powders and granules and provides excellent cleanability. 【Features】 ■ Minimal adhesion of powders and granules, with excellent cleanability ■ Easy installation and removal for containers and piping ■ Adopts a clamp method for quick assembly and disassembly, making cleaning easy *For more details, please refer to the catalog or feel free to contact us.

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Rainproof equivalent to IP67! It has been reborn with an indicator that excels in visibility!

We would like to introduce our diaphragm valve limit switch box, the 'MDNB Series', specifically designed for air-operated drive units. The indicator of the conventional model has been changed from a rubber cap to a bright red, dedicated resin indicator, improving visibility. This is a compact product with a direct mount type that incorporates a micro switch. 【Features】 ■ Direct mount type with built-in micro switch ■ Changed the indicator from a rubber cap to a bright red, dedicated resin indicator ■ Improved visibility due to the change in cap shape *For more details, please refer to the PDF document or feel free to contact us.

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Introduction of lining products that prevent deterioration from corrosion and chemicals!

Introducing the "Lining Type Diaphragm Valve" with excellent resistance to corrosion and chemicals. It is utilized in a wide range of fields such as chemicals, environmental and water treatment, pharmaceuticals, and semiconductors. It can be applied to countermeasure against corrosive fluids, gap corrosion, and metal ion elution. 【Product Lineup (Example)】 "Model 430": Hard natural rubber lining on a base material of FC200 or FCD-S "Model 459": PFA lining on a base material of FCD-S or SCS13 "Model 460": ETFE lining on a base material of FCD-S "Model 450": Polyethylene lining on a base material of FC200 "Model 480": Porcelain lining on a base material of FCD-S *Sanitary specification diaphragm valves are also available. *For more details, please refer to the catalog or feel free to contact us.

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Introduction to porcelain lining products with excellent resistance to corrosion and chemicals.

The "480(04) type" is a diaphragm valve made of porcelain lining that excels in corrosion and chemical resistance. It does not experience the permeation of chemical liquids, which can be a concern under certain conditions with fluororesin lining or rubber lining. Additionally, it is suitable not only as a corrosion-resistant valve for strong acid fluids but also for highly permeable fluids such as hydrochloric acid and phosphorus trichloride. 【Features】 ■ Does not experience the permeation of chemical liquids, which can be a concern under certain conditions with fluororesin lining or rubber lining. ■ Suitable not only as a corrosion-resistant valve for strong acid fluids but also for highly permeable fluids such as hydrochloric acid and phosphorus trichloride. ■ Base material: FCD-S, Lining: Porcelain *For more details, please refer to the PDF materials or feel free to contact us. (We have English and Chinese versions of the catalog available upon request!)

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Aiming to create environmentally friendly valves... "The entire company is united in promoting the continuous reduction of environmental impact!" "ISO 14001 certification obtained!"

Japan Diavalve Co., Ltd. aims to be a sustainable company that balances environmental activities and economic activities amid the worsening global environmental issues. Recognizing the commitment to environmental conservation as one of the important pillars of its business activities, the company obtained ISO 14001 certification in 2008 and is working together as a whole company on environmental activities. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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We will be exhibiting at the "P-MEC Japan 2025 Pharmaceutical Ingredients and Equipment Exhibition" held at Tokyo Big Sight. During the event, we will showcase various products. We invite all relevant parties to come and visit us. 【Suppliers】 ・LAUDA

Seiko Co., Ltd. will be exhibiting at the "11th Monozukuri World Nagoya" held at Port Messe Nagoya. This exhibition features approximately 630 companies showcasing advanced technologies that contribute to shortening development and manufacturing periods, promoting DX and IT, reducing costs, and enhancing energy efficiency and automation in factories, including IT and DX products, parts, equipment, devices, and measurement products. We plan to display the actual cabinet for equipment management, "SMART BEE," so please be sure to visit us. 【Model Numbers】 ■ Vending Machine Type Tool Management Cabinet Smart Bee X, Smart Bee S, Cute Bee, Smart Bee Pro ■ Locker Shelf Type Tool and Consumables Management Cabinet T Series: T57, T100, T108 TW Series (with electronic scale): TW45, TW68, Hyper S, Hive

We will be exhibiting at "Japan DX Week Spring 2026," which will be held at Tokyo Big Sight from April 8 (Wednesday) to April 10 (Friday). At the Marble booth, we plan to showcase how AI can improve work efficiency and lead to business automation in on-site operations. Additionally, we will provide an opportunity to experience a demonstration utilizing the latest technology, AR. Furthermore, for our manufacturing industry customers, we will present proposals under the theme "Utilizing Drawings to Drive DX," promoting the digitalization of design and quality areas, and introducing packaged products and custom services aimed at enhancing productivity in the manufacturing sector.

Core systems are the foundational support for corporate management, and their importance is increasingly heightened in the DX era, where data becomes a source of competitive advantage. To respond swiftly and flexibly to the rapidly changing business environment, a transformation in the nature of systems is required. We will introduce a method to realize a highly flexible and scalable business system that promotes operational efficiency and data utilization through the combination of kintone and ASTERIA Warp, using examples and demonstrations.

The widespread adoption of generative AI is rapidly evolving from traditional "conversational AI" to "autonomous execution AI (AI agents)." The AI agents that have recently garnered attention are not limited to merely generating responses; they can incorporate an autonomous processing flow of "planning → task decomposition → execution → evaluation," serving as new partners that can substitute and expand users' business operations. In this seminar, we will clearly introduce the following topics, incorporating examples of the AI solution "AIdea Suite AGENT +plus" and the data integration tool "ASTERIA Warp": - Why "AI agents" are becoming essential for corporate competitiveness now - The mechanisms of AI agents and specific use cases - Methods for establishing business efficiency, creating new value, and gaining a competitive edge - Specific steps for implementing AI agents - Data integration and its methods, which are essential for utilizing AI *This is a re-broadcast of the seminar held on October 30, 2025 (Thursday).