The new application report highlights that high-throughput APC recordings of hippocampal neurons are promising for improving treatment of cognitive dysfunction, psychosis, and schizophrenia.

High-throughput APC recordings of hippocampal neurons highlight their promise in improving treatment for cognitive dysfunction, mental illness, and schizophrenia.

A PhD from the University of Copenhagen has made significant progress by using the Qube 384 automated patch clamp (APC) platform to record α5-containing GABAA receptors from acutely isolated primary neurons. This research highlights the importance of using natural primary hippocampal neurons to evaluate the effects of antipsychotic drugs on GABAergic activity, particularly from the perspective of drug discovery for cognitive function and schizophrenia. Previous studies relied on heterologous expression systems, such as HEK cells expressing α5-containing GABAA receptors. However, this research emphasizes the value of investigating these effects in primary hippocampal neurons, which more accurately reflect physiological conditions. *For more details, please refer to the related links. Feel free to contact us for further information.*

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The "Mechanical Stitching Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact to the base material. Repairs can be carried out even in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

This is an introduction to "outer diameter film polishing," which is used for ultra-finish machining of various shaft-type workpieces. - Wouldn't you like to achieve ultra-finish machining more easily, safely, and with less variation? Please take a look at what film polishing is, along with related products and catalogs!

The "Mechanical Stitching Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed without causing any thermal impact on the base material. Repairs can be made even in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

We are pleased to announce that Tokyo Machine Works Co., Ltd. will be exhibiting at the "INNOVATION EXPO 2025" to be held at Tokyo Big Sight from September 10 (Wednesday) to September 12 (Friday), 2025. 【Exhibited Equipment】 - 1-ton portable autonomous mobile robot (AMR) - 2-ton portable unmanned transport vehicle (AGV) - Shutter-equipped unmanned transport vehicle - Autonomous cleaning robot, etc. 【Booth Number】 - 6-405 You will have the opportunity to see each machine up close, including demonstrations that link the equipment together. We sincerely look forward to your visit during this event. Please note that pre-registration (free of charge) is required to attend the exhibition, so we kindly ask you to register using the link below. https://www.logistech-online.com/jp/registration.php?exhibitor=EX000072 If you would like an invitation, please request it through our contact form.

Contec has added a BTO menu for the Windows 11-based embedded OS - Windows 11 IoT Enterprise LTSC 2024 to its industrial computer "MR4310 series" and has started accepting orders.