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  3. アズフレイヤ Medical Institute for Translational Health Sciense
  4. Tulsi (Holy Basil) callus-derived exosomes - New cosmetic ingredient development! Now available!
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  • Aug 21, 2025
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Aug 21, 2025

Tulsi (Holy Basil) callus-derived exosomes - New cosmetic ingredient development! Now available!

アズフレイヤ アズフレイヤ Medical Institute for Translational Health Sciense
ASFREYA Co., Ltd. has been conducting research and development on how exosomes derived from plants and animals affect humans, including the miRNA and proteins contained within exosomes. We are pleased to announce that we have successfully extracted plant exosomes using our unique "callus culture" technology and have completed the INCI registration for cosmetic ingredients. We have successfully cultivated "callus," which is the undifferentiated cells of the herb "Tulsi (Holy Basil)," highly valued in Ayurveda as a "miraculous plant," and we will begin handling exosomes derived from Tulsi callus.
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INCI obtained plant-derived cosmetic ingredient 'Tulsi Exosome'

A plant-derived ingredient with high concentration, excellent antioxidant and anti-inflammatory properties. An exosome material that addresses a wide range of concerns for skin and scalp, including fine lines, dullness, inflammation, and hair loss.

Exosomes are small capsules with a diameter of 50 to 100 nm that are secreted by cells. They are rich in signaling molecules such as RNA and proteins, playing a crucial role in intercellular communication. "Truly Exosomes" are derived from Tulsi, known as the "Queen of Herbs," which has many pharmacological effects without side effects. They contain high concentrations of exosomes and support the health of the skin and scalp from multiple angles. 【Main Expected Effects】 ✓ Skin barrier and moisture retention improvement: Stabilizes cell adhesion for skin that is resilient to external stimuli. ✓ Anti-inflammatory effects: Reduces redness, itching, and swelling. ✓ Anti-aging: Promotes collagen synthesis and suppresses excessive fiber activity to prevent skin aging. ✓ Wound recovery support: Prevents excessive scar formation and promotes natural healing. ✓ Moisturizing and sebum regulation: Increases ceramide synthesis, improving oily skin and clogged pores. ✓ Stress and environmental resilience enhancement: Supports oxidative stress response and immune function. High-concentration exosomes derived from Tulsi can be incorporated into skincare, haircare, and makeup products. With multifunctionality based on the latest research, they also contribute to the differentiation of products under development. < For detailed ingredient information and application examples, please download the catalog from the link below. >

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Eliminate skin and hair concerns with plant-derived exosomes! Two trending cosmetic ingredients.

Plant-derived ingredients that provide broad support for beautiful skin, anti-aging, and hair growth. Based on research data, they offer multifunctionality and contribute to the differentiation of cosmetics in development.

Exosomes are small capsules with a diameter of 50 to 100 nm that are secreted by cells. They are rich in signaling substances such as RNA and proteins, which help maintain the health of the skin and scalp. The two types of plant-derived exosome materials introduced here can broadly approach beauty, anti-aging, and hair growth by leveraging their respective characteristics. 【Dragon Fruit Exosome】 Suppresses UV rays and aging signals Reduces skin yellowness and creates a brighter tone Promotes collagen and elastin synthesis for improved firmness and elasticity Improves fine lines and sagging, strengthens the skin barrier 【Tulsi Exosome】 High concentration with antioxidant and anti-inflammatory effects Reduces redness, itching, and swelling Enhances skin barrier and moisture retention for healthier skin Supports scalp care and hair growth, improves resistance to environmental stress Both can be incorporated into skincare, hair care, and makeup products, contributing to differentiation and multifunctionality in product development. < For detailed ingredient information and application examples, please download the materials from the link below. >

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Azufureiya Co., Ltd. - Company Overview

Azufureiya Co., Ltd. - Company Overview

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Azufureiya Research Institute, Inc.

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[Cast Iron Repair] We will repair cracks that have occurred in metal equipment without applying heat.

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The "Mechanical Stitching Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact on the base material. Repairs can be carried out in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

May 08, 2026

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[Cast Iron Crack Repair] We repair cracks in metal products without applying heat.

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The "Mechanical Stitching Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact to the base material. Repairs can be carried out in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

May 08, 2026

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Aluminum prototype: Lost wax casting sand mold layered 3D printer prototype.

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● The production time for casting prototypes can be shortened! Since model production is not required, the time needed to create prototypes, which previously took about a month, can be significantly reduced. ● Model costs can be reduced! By directly producing sand molds from 3D data, there is no need for model production costs. If changes to the model are necessary, they can be addressed by modifying the 3D data. ● Similar products with different shapes and dimensions can be prototyped simultaneously! With one molding process, different products with similar shapes or varying dimensions can be molded at the same time. This allows for the verification of multiple types in a short period.

May 08, 2026

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[To the design office] Are you struggling to explain "safety" to the client using only drawings?

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Are you struggling to explain "safety" to the client using just drawings? - The risks in blind spots are difficult to convey to the client through drawings alone. - Safety measures often become a target for cost reduction, making it hard to communicate their necessity. - There is a concern that the client might say, "It's more dangerous than I thought," after completion. Risks that are visible to design professionals are not easily understood intuitively by clients who are outside the field. This document is not just a simple explanation of sensor functions; it is a guide to visually explain "why sensors are necessary in that location." It can be used directly as explanatory material for the client. Here are three key points for utilizing this document: 1. Visualization of Risks Blind spots during vehicle departure and contact risks within the site are illustrated clearly. 2. Clarification of Selection Criteria A comparison table outlines the differences between complex sensor types such as infrared, ultrasonic, and loop coils. 3. Diagram of System Configuration It illustrates not just the sensors alone, but how they combine with components like rotating lights and control panels, providing practical assistance for electrical equipment design. Please make use of this to prevent "rework after completion" and "accident risks."

May 08, 2026

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[Free Catalog Distribution] Measures against "Near Misses" in Nursing and Care Settings. Prevent tripping and disconnection with codes! Wireless Series Bed Exit Sensors Linked to Nurse Call Systems.

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In facilities operating nurse call systems, we have made the bed exit sensor wireless, allowing it to notify in conjunction with the nurse call system. By simply connecting the mat sensor "Foldable Thin Matt-kun," the body movement call "Ugo-kun," and the wheelchair body movement call "Ayumi-chan" to the transmitter HB-RS, you can make the bed exit sensor wireless. The infrared sensor "Just Place Pole-kun" has the transmitter HB-RS built-in. This helps prevent accidents caused by falls, slips, or wandering, contributing to the efficiency of medical operations. 【Features】 ○ Wireless conversion by simply connecting existing sensors to the transmitter HB-WSK. ○ The bed exit sensor notifies wirelessly in conjunction with the nurse call system. ○ Up to 5 transmitters can be registered with a single receiver. ○ The communication distance between the transmitter and receiver is approximately 10 meters. ◎ For more details, please contact us or download the catalog.

May 08, 2026

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  • 展示会出展等の販売促進に必要な費用を助成します! 最大300万円 助成率1/2以内 市場開拓助成事業 展示会等参加費・印刷物制作費・動画制作費 など 申請受付:令和8年 5/15(金)~5/29(金)
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