Notice of Exhibition at the 54th Annual Meeting of the Japanese Society of Environmental Mutagenesis and Genomics

Toxicity prediction from compound structural information! - Compliant with ICH M7 guidelines for food health impact assessment -

It is a type of "Quantitative Structure-Activity Relationship (QSAR)" software developed in collaboration between MultiCASE and the FDA/CDER, which predicts toxicity from the 2D structural information of compounds. CASE Ultra has two complementary types of (Q)SAR models: knowledge (rule)-based and statistical-based, and it is capable of complying with ICH M7. Additionally, it allows for the creation of new predictive models using proprietary data and the enhancement of existing predictive models. 【Features】 ■ Joint research and development with FDA/CDER ■ Alternative to cell tests and animal experiments ■ Provides analogs based on alert surrounding structural environments ■ Supports expert judgment ■ Lead across 【Predictable Endpoints】 - Mutagenicity - Genotoxicity - Carcinogenicity - Hepatotoxicity - Nephrotoxicity - Cardiotoxicity - Dermal and ocular toxicity - Reproductive and developmental toxicity - Acute toxicity - Ecotoxicity - Endocrine receptor binding and many more.

• Other research software

Search all databases and literature information worldwide at once!

ToxPlanet is an integrated search platform that encompasses toxicity and hazard information for chemical substances. It features an intuitive interface and covers information on over 110 million compounds from more than 1,300 data collections, over 700 regulatory and advisory lists, and more than 10 million literature references. By obtaining comprehensive toxicity and hazard information for chemical substances from a single search key, it reduces investigation time and workload in safety research and risk assessment tasks, while enhancing the quality of the investigation.

• Other research software

It is possible to evaluate the acceptable intake levels of nitroamines and predict nitrosation.

QSAR Flex enables the prediction of complex toxicity using quantitative structure-activity relationships (QSAR) and read-across methods. In particular, the following models can be utilized to support the carcinogenicity assessment of nitrosamines: - Support for AI value evaluation based on CPCA - Support for AI value estimation through read-across - Prediction of nitrosamine generation from compounds and synthetic pathways Various methods for evaluating nitrosamines can be conducted solely with QSAR Flex.

• Other research software

More innovatively! A platform built by scientists for scientists.

"Labstep" is a user-friendly and flexible electronic lab notebook (ELN) that captures all research-related data and metadata in real-time. It provides the capture and analysis of structured data in a safe and collaborative environment, supporting the creation and protection of intellectual property by research and development labs. By utilizing an open API, it allows for digital connections with instruments, devices, and systems, enabling direct integration into experimental records. 【Features】 ■ Modern and easy to use ■ User-friendly and flexible utilization ■ Provides capture and analysis of structured data in a safe and collaborative environment ■ Supports the creation and protection of intellectual property by research and development labs ■ Allows for centralized management of all experimental notes, protocols, samples, inventory, devices, and order management.

• Other quality control systems

We are pleased to announce that we will be exhibiting at the exhibition "TOYO One-Man Show 2026" hosted by Toyo, as detailed below. We regularly share information on our website and various social media platforms, but this will be a great opportunity for you to see the actual measuring instruments. We sincerely invite you to attend. Date: January 28 (Wed) and 29 (Thu), 2026, from 10:00 AM to 8:00 PM Venue: Kariya City Industrial Promotion Center (1-1-6 Aioi-cho, Kariya City, Aichi Prefecture, a 5-minute walk from JR Kariya Station) Exhibiting manufacturers: Approximately 75 companies Registration URL: https://www.tenjikai-uketsuke.com/form/toyo-show2026/visitor *Please note that pre-registration is required, so we kindly ask you to register in advance via the web.

Do you want to use SOLIDWORKS more conveniently but think, "API seems difficult..."? How about trying to create a macro together? The theme is "Automating just one process." This time, we will create a system that automates the simple task of "saving," which you do manually every time in SOLIDWORKS, so that it can be completed with one click. Even if you have never written code before, that's okay. By simply "tracing and creating together" the necessary parts, you will be able to experience the excitement of actual automation in action. Through this webinar, I hope you will realize, "Oh, I can start with something this small in API." ■ Recommended for: - Those who do not fully understand how to utilize SOLIDWORKS API - Those who are not familiar with macros - Those who want to automate their design processes - Those who want to reduce human errors, even just a little.

[Speaker] Associate Professor Naoshi Matsuhisa, Center for Advanced Science and Technology, The University of Tokyo [Key Lecture Content] Various soft and stretchable electronic materials that break the common belief that rubber does not conduct electricity are being developed. Electronics made with these materials are expected to be utilized as next-generation wearable devices that are soft like skin, provide excellent wearing comfort, and enable long-term health monitoring. This lecture will introduce the forefront of soft and stretchable electronic material development, as well as the creation of entirely new healthcare human-computer interfaces that integrate with the skin. [Lecture Items] 1. Soft and stretchable electronics 2. Ultra-flexible electronics that accompany people 3. The forefront of diverse stretchable electronic material development 4. Sensors and displays that integrate with the skin 5. Ultra-flexible semiconductor devices using stretchable semiconductor materials 6. Next-generation wearable devices that integrate with the skin 7. Summary 8. Q&A / Business card exchange

[Lecturer] Yoshiaki Otsuki, Special Counsel, Anderson Mori & Tomotsune Law Office, Foreign Law Joint Enterprise [Key Lecture Content] Rare earth elements are metallic minerals commonly used in electric vehicles (EVs) and smartphones, but it is said that a large portion of their production relies on China. However, in light of the recent intensification of U.S.-China tensions and other international circumstances, concerns have arisen regarding the security of rare earth supply. In this context, the development of rare earth projects within Japan's territorial waters or exclusive economic zone (EEZ) has suddenly come into the spotlight. This lecture will focus on the legal aspects of rare earth development projects within Japan's territory, particularly addressing the application issues of the Mining Act, which was amended in 2022. [Lecture Topics] Chapter 1: Introduction - International Situation Surrounding Rare Earths Chapter 2: Application of the Mining Act Regarding Rare Earth Development in Japan's Territory Chapter 3: Future Outlook Q&A / Business Card Exchange

[Speaker] Mr. Daiki Kaneda, President and CEO of AXIA Marketing Co., Ltd. Mr. Atsushi Nagata, Director [Key Lecture Content] With the rise of manufacturers from emerging countries, the modern era is reaching its limits in competition based solely on specifications and price. The key for Japanese manufacturing industries, such as automotive parts, industrial machinery, semiconductors, chemicals, and steel, to regain growth in the global market lies in a "deep understanding of local technology trends and regulations" and a strategy that "avoids falling too deeply into price competition and transforms into added value." In this lecture, we will explain, using specific examples, how to avoid and leverage the latest local needs and pressures of technology transfer, and how to earn trust. [Lecture Topics] 1. The harsh reality of the global market and the redefinition of "reasons to be chosen." 2. Development strategies to break through the pressures of technology transfer and institutional barriers. 3. Game-changing material selection: the forefront of decarbonization and ESG compliance. 4. Learning from successful cases: a roadmap for market development and a "key" to execution. 5. Q&A session.