[Sending Recorded Video] Services Offered by Sartorius - Introduction to Cell Line Development, Cell Banking, and Various Tests.

Using Cellca cell line development, over 120 projects have been successfully completed.

Zaltrius is a top provider of cell line development services. It offers cost-effective and highly reliable technology platforms. Cellca cell line development consistently delivers clones for stable research cells that have undergone sufficient characterization. From DNA to research cell banks (RCB) in just 14 weeks, it achieves a minimum monoclonal antibody titer of 5g/L with a scalable fed-batch process.

• others

Conducted safety and characterization analysis tests on over 200 Chinese hamster ovary (CHO) cell bank samples.

CHO cells are the most widely used production cell lines in the pharmaceutical industry, and their safety profile has been established for over 20 years. Guidelines for the safety and characterization analysis of CHO production cell lines are harmonized with the International Conference on Harmonisation (ICH) Q5 (R1) "Virus Safety Evaluation of Biotechnology Products Derived from Cell Lines of Human or Animal Origin" and ICH Q5D "Derivation, Characterization, and Production of Cell Lines for the Manufacture of Biological Products (Biotechnology-derived Products | Biologically-derived Products)." Since 2007, Sartorius has conducted safety and characterization testing for over 200 Chinese Hamster Ovary (CHO) cell bank samples. Our researchers possess extensive knowledge and experience and will provide advice on optimal and cost-effective testing strategies that comply with chemical and regulatory requirements. We will also consider the history of the cell lines and raw materials used during bank manufacturing when proposing test packages.

• others

Introducing comprehensive solutions for safety testing of biological products and viral vaccines.

All biological products must undergo rigorous safety testing at both the development and manufacturing stages to confirm the characteristics of the product and host cells, as well as to ensure non-contamination. ▪ Exceptional technical expertise ▪ Rapid result delivery ▪ Extensive regulatory knowledge ▪ Enhanced quality assurance

• others

Integrated services with expertise and industry leadership.

【Top Service Provider】 The foundation for the approval of new biopharmaceuticals is built on a robust analytical data package that demonstrates the safety, purity, and efficacy of the product. BioOutsource's analytical testing package combines physicochemical and biological analytical methods, allowing for detailed characterization tailored to each client. 【Client Management Organization】 Projects are carried out by cross-departmental teams, and client managers provide support and advice with high transparency throughout the entire lifecycle of the client's project. 【Industry-Leading Integrated Services】 By supporting the development and characterization of biopharmaceuticals from preclinical development to commercialization, we provide services tailored to our clients' needs.

• others

Next-generation GMP cell banking

Thorough characterization and documentation of similar master cell banks (MCB) and working cell banks (WCB) are crucial elements that lead to risk reduction and ensure the safety and product quality of all biologically derived products. An experienced team is leveraging CRO expertise to expand services such as cell bank manufacturing. ▪ Manufacturing in a closed system ▪ Quality assurance ▪ Integration into cell line development and biosafety services ▪ For your applications: from mAbs to vaccines

• others

Comprehensively supporting the early development of biopharmaceuticals on an independent platform.

Physical and Chemical, as well as Biological Equivalence of Biosimilars | Similarity Assessment 【Expertise】 Industry-leading experience with over 12 biosimilar molecules and more than 30 biosimilar development companies 【Speed to Market】 Cost-effective results guaranteed through a comprehensive lineup of ready-made assays for the characterization and equivalence | similarity assessment of biosimilars 【Higher Quality Assurance】 Providing the necessary data for submission at the time of application, backed by exceptional regulatory and industry insights

• others

We will be exhibiting at the joint company information session hosted by Mynavi on the following schedule. We will clearly explain the four core businesses of Takaya. If you are interested in "monozukuri" (manufacturing), please come to our booth!

At this exhibition, we will introduce our materials equipped with new functions and values that contribute to solving our customers' challenges. Our mid-term management plan includes "securing competitive advantage through technology leadership" as one of its basic strategies, and our engineers, who embody this strategy, will explain and propose the exhibited products in their own words. We would love to hear your feedback, so please feel free to stop by our booth.

[Speaker] Naoki Toda, Chief Economist, Management Strategy Research Office, Tokyo Electric Power Company Holdings, Inc. [Key Lecture Content] Since the 1990s, the global advancement of power system reforms has aimed for efficiency and optimization in both the operation and investment of facilities through active market competition. However, with the progress of DX/GX, the anticipated scenarios for electricity demand have led to the emergence of underinvestment issues worldwide. The IEA's report "Electricity Market Design," published last year, provides a comprehensive review of the reform situations in various countries and indicates that the underinvestment problem is a common issue across the globe. In this lecture, I will explain the current state of the underinvestment issue and potential responses from a business system perspective, referencing the IEA report and others. [Lecture Items] 1. Background of power system reforms and the underinvestment issue 2. About IEA "Electricity Market Design" 3. Reflecting on the thoughts of Akihiro Sawa on the 10th anniversary of his passing 4. Possible solutions to the Tenor Gap issue 5. Outlook for Japan's power system 6. Q&A / Business card exchange

[Instructor] Shinichiro Takiguchi, Senior Specialist, Innovation Strategy Center, Japan Research Institute, Inc. [Key Lecture Content] With the increase in renewable energy, the introduction of energy storage systems has progressed in two forms: renewable energy co-located systems to adjust power generation fluctuations, and demand co-located systems to secure electricity during grid outages. However, the landscape is changing significantly. The "Supply and Demand Adjustment Market" has been established by OCTTO (Organization for Cross-regional Coordination of Transmission Operators), and particularly due to the continued high pricing agreements in the short-term response market (primary adjustment power responding within 10 seconds), there have been numerous cases where battery storage profits are secured through market transactions. In the grid energy storage business, two capabilities are required: "trading power" and "financial power." This lecture will explain the business structure and key points of profitability. Additionally, based on this business structure, we will classify the companies entering the grid energy storage business and organize the market structure of this sector. As this business is influenced by regulatory trends, we will also discuss regulatory outlooks. Finally, we will talk about future prospects.

[Lecturer] Professor Yoshiharu Nishimura, Senior Researcher, Kansai Electric Power Co., Inc. Graduate School of Engineering, Osaka University, Business Engineering Program [Key Lecture Content] The examination of the next-generation power infrastructure conducted in 2025 has entered the implementation phase, including amendments to the Electricity Business Act, towards a new power policy standard (a sustainable framework by responsible players) in 2026. This lecture will outline the content and related policy adjustments for businesses involving renewable energy and storage batteries, and consider the correct business concepts, necessary timelines, and how to create business models moving forward. [Lecture Items] 1. What is the 2026 Next-Generation Power Infrastructure Reconstruction? 2. Renewable Energy and Decarbonization Policies and Issues with Chinese Products 3. The Latest Status of Storage Batteries and the Timeline and Vision for DER Business 4. Q&A / Business Card Exchange