Analytical device for evaluating polymer characteristics in solution.
The analytical ultracentrifuge Optima AUC is the most versatile, rigorous, and precise analytical device for demonstrating the molecular weight and fluid dynamic and thermodynamic properties of not only proteins but also other substances. It can determine the molecular weight, size, shape, and polydispersity of solute particles based on their sedimentation behavior, and it can also analyze interactions between particles in their natural state without the need for a carrier. ●● Advantages of AUC ●● - Sample recovery is possible (non-destructive analysis) - Detection at low concentrations - Small sample volume (minimum amount: sedimentation velocity method 100 μL, equilibrium method 25 μL) - No standard samples required - Simple operability *For more details, please refer to the PDF materials or feel free to contact us.
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basic information
Compared to other techniques that can analyze large molecules such as protein complexes, AUC allows for the characterization of molecules under solution conditions where they exist in their native state. AUC has been used to analyze almost all types of molecules and particles in a wide range of solvents and concentrations. AUC has two complementary methods, and by optimally utilizing these methods, it is possible to analyze the properties of molecules in solution. The sedimentation velocity method provides very important hydrodynamic information about molecular size and approximate shape, while the sedimentation equilibrium method provides information about the molar mass, stoichiometry, binding constants, and non-ideality of the solution. *For more details, please refer to the PDF document or feel free to contact us.*
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Applications/Examples of results
- Development of virus vectors - Analysis of protein properties - Evaluation of pharmaceutical characteristics - Confirmation of aggregates (dispersion and aggregation evaluation) - Interaction analysis *For more details, please refer to the PDF document or feel free to contact us.*
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Company information
Our company is a global company headquartered in the United States, operating in over 120 countries worldwide. We are structured around three fields: life sciences, clinical testing, and particle properties, offering a wide range of products, services, and solutions. Products in the life sciences field are provided to researchers at bio-related companies, universities, and vocational schools to study diseases and new treatment methods, as well as to address complex biological issues. Products in the clinical testing field are utilized by clinical laboratory technicians in hospitals and medical facilities around the world to diagnose patients by obtaining necessary information from blood samples. Products in the particle properties field are adopted for industrial applications in manufacturing facilities where measuring particles is essential.