Abnormal data in a patent?! Ultra-sensitive microcalorimeter!
【DSC Series】 The Differential Scanning Calorimeter MicroCal DSC Series evaluates the stability of proteins and other biomolecules in solution. It directly measures extremely small thermal changes occurring within biomolecules under temperature-controlled conditions. ～*～*～*～*～*～*～*～*～*～*～*～* 【ITC Series】 The Isothermal Titration Calorimeter MicroCal ITC Series is used to extensively investigate the interactions of biomolecules. It directly and label-free measures binding affinity and thermodynamic parameters in solution. With ultra-high sensitivity, it captures changes that would typically be overlooked, leading to instances that have resulted in patent applications! *We hold individual consultation sessions every month. These sessions are open not only to those who already own our products but also to those planning to purchase them, so please feel free to contact us. Online consultations are also available.* Details of the individual consultation session: https://www.malvernpanalytical.com/jp/about-us/press-releases/news/PRJP21annualpersonaltraining.html
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basic information
The transfer of the MicroCal product business from GE Healthcare Japan, Inc. has been completed, and Malvern has been handling MicroCal products since July 2014. 【Point】 - No labeling reagents required - Acquisition of denaturation midpoint temperature and thermodynamic parameters - Evaluation of the stability and equivalence of samples in solution - Full automation control of all functions such as sample filling and cell cleaning
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Applications/Examples of results
Interactions of proteins and other biomolecules Structural analysis of proteins and other biomolecules 【DSC Series Application Examples】 - Stability evaluation of biopharmaceuticals - Formulation studies based on the stability of biopharmaceuticals - Equivalence evaluation of biopharmaceuticals - Thermal stability evaluation of proteins - Thermal stability evaluation of each domain of proteins - Stability evaluation of diffusion, lipids, polymers, etc. ☆ Proteins, diffusion, viruses, vaccines, lipids/liposomes, carbohydrates, colloids, polymers ～*～*～*～*～*～*～*～*～*～*～*～* 【ITC Series Application Examples】 - Interaction analysis of various molecules in solution Protein-protein Low molecular weight-low molecular weight - Drug design - Fragment Based Drug Discovery (FBDD) - Enzyme kinetics ☆ Proteins, diffusion, low molecular weight compounds, vaccines, lipids, carbohydrates, colloids, surfactants, polymers ○o｡+..:*○o｡+..:*○ The brochure includes measurement examples with graphs, so please download it! ○o｡+..:*○o｡+..:*○
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We are the Japan division of Malvern Panalytical, a company that provides particle measurement devices and X-ray analysis equipment. Based in Tokyo and Kobe, we have a total of six sales offices and two application laboratories across the country, where we offer sales, services, and support for particle measurement and X-ray analysis devices, as well as various events such as seminars. Malvern, which has products in particle measurement and thermal analysis (calorimetry), merged with Panalytical, a manufacturer of X-ray diffraction and fluorescence X-ray analysis equipment, in 2018. The integration of these two leading companies in their respective fields allows us to provide cutting-edge solutions to a wide range of industries involved in R&D, process control, quality management, and material property analysis.
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