Protein solubilization reagent MPEX PTS Reagents

Optimal solubilization reagents for analyzing membrane proteins using mass spectrometry (MS).

This is a solubilization reagent kit designed for the easy analysis of membrane proteins using mass spectrometry. Membrane proteins are said to be targets for many pharmaceuticals and are expected to be one of the protein groups that will see increasing research in the future. However, in analyses using mass spectrometry, it has been technically and temporally challenging to easily analyze them due to issues such as the removal of solubilizing agents and the inactivation of digestive enzymes. By using this product, which has a high solubilization capacity, membrane proteins can be easily solubilized without the need to consider different types of solubilizing agents. Even difficult-to-solubilize membrane-spanning proteins can be easily solubilized, and trypsin digestion can be performed in the presence of MPEX reagents. MPEX reagents can remove surfactants based on the principle of liquid-liquid extraction. It is possible to extract membrane proteins from membrane fractions of cell lysates, such as those from cultured cells, and analyze them using mass spectrometry. Features: - Higher solubilization capacity compared to Triton and Tween. - Does not inhibit the activity of digestive enzymes such as trypsin. - Easy removal method (liquid-liquid extraction).

Protein Extraction Kit