International standard for measuring particle size and concentration of exosomes/microvesicles.
NanoSight allows for real-time observation of the Brownian motion of nanoparticles in liquid on a PC screen using NTA (Nanoparticle Tracking Analysis) technology. Recently, in exosome research, NanoSight has provided new insights by detecting exosomes and counting particle numbers through its unique features and technology. ■ Adoption of unique measurement technology "Nanoparticle Tracking Analysis (NTA)" A proprietary measurement method from NanoSight that calculates particle size based on the Brownian motion of each particle. ■ Measurement of individual nanoparticles/exosomes Instead of using averaged particle sizes obtained from fluctuations in scattered light intensity, it measures and displays the size of individual particles. ■ Visual observation of particle scattered light Real-time observation of the Brownian motion of nanoparticles in liquid on a PC screen is possible. ■ No need for refractive index or reflectivity information Samples with unknown surface property data, such as newly developed materials, surface coatings, and biomaterials, can be measured accurately.
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basic information
■Application Example: Detection and Counting of Exosomes NanoSight can accurately measure the size and concentration of exosomes/microvesicles. Additionally, by using fluorescent labels such as quantum dots, it is possible to selectively detect and analyze specific particles from a bulk sample. It can also be used to examine the degree of cell purification. Research on biological nanoparticles has been limited due to a lack of appropriate characterization methods, but NanoSight's unique features and technology are leading to new insights. The "Nanoparticle Tracking Analysis (NTA)" method employed by NanoSight visualizes exosomes/microvesicles (50–1000nm), counts them in real-time, and measures particle size distribution profiles and concentrations. Thus, the NTA technology is an attractive device compared to existing methods due to its simplicity, speed, high precision, and low cost.
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DDS, drug discovery, virus, protein aggregation, emulsion
Company information
Our company was established as the Japanese subsidiary of a foreign-affiliated manufacturer with a global network spanning over 40 countries. We are steadily expanding our business primarily through the sale of SQUID magnetic property measurement devices and physical property measurement devices, which boast a world-class share in the field of new material research and development. Additionally, we also operate as a trading company for high-tech scientific instruments, importing and selling cutting-edge research equipment from around the world in various fields such as material science, biotechnology, and nanotechnology. The wave of technological innovation is significantly transforming not only industrial sectors but also our daily lives. Among these, the fields of material science, biotechnology, and nanotechnology, which are the pillars of our business, can be described as "core technologies" that provide humanity with infinite possibilities for the future as they lead the way in cutting-edge technology (high-tech). The discovery of high-temperature superconducting materials, applications of laser microfabrication and optical communication, and surface analysis at the nanoscale are already playing important roles in various fields such as new materials, semiconductors, information and communication, medical care, clinical diagnostics, and drug discovery, while also enabling further advancements in technology.
