We will utilize various key technologies to support a range of contract synthesis under GMP compliance!
At Kongo Chemical Co., Ltd., we offer various contract synthesis services under GMP compliance. We can accommodate ultra-low temperature reactions down to -90°C and high-temperature reactions up to 220°C. Examples of C-C bond formation include alkylation reactions using NaNH2 and the Hummock reaction (high-temperature reaction), as well as examples of C-O and C-N bond formation such as dehydration etherification reactions. Please feel free to contact us if you have any requests. 【Features】 ■ Ultra-low temperature reactions: Capable of -90°C ■ High-temperature reactions: Capable of 220°C ■ Contact reduction: One pressure ■ Other organic synthesis *For more details, please contact us.
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【Examples of Reactions】 ■ Examples of C-C Bond Formation - Alkylation reaction using NaNH2 - Hammick reaction (high-temperature reaction) - Friedel-Crafts acylation reaction, etc. ■ Examples of C-O and C-N Bond Formation - Dehydrative etherification reaction - Williamson ether synthesis (high-temperature reaction), etc. ■ Examples of Oxidation and Reduction Reactions - Hydrogenation reaction (contact reduction) - Stereoselective reduction (low-temperature reaction) - Reduction using metal complexes (NaBH4, DIBAL, etc.), etc. ■ Optical Active Compounds - Diastereomer method (racemization) - Asymmetric aldol reaction *For more details, please contact us.
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Kongō Chemical Co., Ltd. is a company primarily engaged in the manufacturing of active pharmaceutical ingredients (APIs). In order to accelerate the expansion and strengthening of contract manufacturing and generic drug development, we are enhancing our medium and large-scale contract manufacturing facilities and implementing cleanroom construction for API compatibility, thereby improving our acceptance system. We will continue to make constant efforts towards technological advancement to contribute to the evolution of chemistry and life.