Through mapping analysis, we will clarify the elemental distribution in biological samples.
We will conduct elemental mapping analysis using LA-ICP-MS (Laser Ablation/ICP Mass Spectrometry).
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basic information
Features of LA-ICP-MS ■ High sensitivity and rapid analysis ■ No sample preparation required, allowing for nearly non-destructive analysis ■ Direct analysis of difficult-to-dissolve solid samples ■ Localized analysis possible ■ Depth profiling, line analysis, and area analysis (element mapping analysis) ■ Capable of analyzing from trace amounts (a few ppm) to high concentrations (a few %) ■ Simultaneous multi-element analysis possible
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Applications/Examples of results
■Example of Element Mapping Analysis ● The location of platinum formulations administered to rats can be estimated from the distribution of Pt in renal tissue. ・It is possible to grasp the elemental distribution in thinly sliced biological samples. ・Mapping analysis can clarify the accumulation of elements in tissues and the distribution of components derived from administered therapeutic agents. ・Compared to SEM-EDX (scanning electron microscopy) and EPMA (electron probe microanalyzer), highly sensitive analysis (sub-number) is possible. ・Light elements such as phosphorus, magnesium, and sodium can also be observed. ・No sample pretreatment such as deposition is required (just set the sample in the analysis cell).
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To solve your technical challenges in a ONE-STOP manner, our team of 1,300 technical specialists will respond quickly and accurately while maintaining strict confidentiality. With bases in six locations nationwide, our experts in various fields utilize the latest analytical testing equipment to meet all your needs. We are confident that we can provide results that will satisfy you, and we would be grateful if you could give us a try.