Support for safety testing from the screening stage to entering clinical trials!
Inari Research supports safety testing from the screening phase to the entry into clinical trials (clinical studies). In addition to core battery tests based on guidelines, we can propose various follow-up tests and supplementary safety pharmacology tests. With the testing techniques and know-how cultivated over many years, we will suggest appropriate test designs. We also conduct specialized tests such as dependency tests on macaques and rats in the central nervous system. [Central Nervous System Examples] ■ General Condition (Dogs, Cynomolgus Monkeys) - Action search based on the drug's action characteristics ■ Motor Coordination (Mice, Rats) ■ Spontaneous Activity (Mice, Rats) ■ Anesthesia Cooperation/Antagonism (Mice, Rats) - Drug effects under pentobarbital anesthesia ■ Pain Sensation (Mice, Rats) - Tail flick method, pressure stimulation method, etc. ■ Catalepsy Observation (Mice, Rats, Dogs, Macaques) - Searching for catalepsy-inducing effects based on the duration of standing posture, etc. ■ Aversion Effect Tests (Macaques) - Searching for aversion effects through lever-pressing behavior, etc. *For more details, please refer to the PDF materials or feel free to contact us.
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basic information
The study will be conducted at a GLP-compliant facility that has obtained certification from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International). A series of non-clinical study sets, including genotoxicity tests and safety pharmacology tests necessary to enter clinical trials (Phase I), can be completed with the final report prepared within six months. *For more details, please refer to the PDF materials or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Company information
Our company is located in the nature-rich city of Ina, Nagano Prefecture, surrounded by two Alps, and has been serving our customers as a non-clinical trial contract research organization (CRO) for 50 years. Since 2022, we have become a member of the Shin Nippon Science Group, expanding and enhancing our contract testing items and analyses, and we can quickly respond to the procurement of various testing materials (such as animals). Non-Clinical Trial Business We accept safety and efficacy testing for pharmaceuticals, chemicals, pesticides, food, medical devices, and more. We conduct in vivo tests using small animals, rabbits, dogs, and monkeys, as well as in vitro tests using bacteria and cells, and various alternative method tests. Additionally, we specialize in the creation of SEND data required for FDA applications for new drugs, and we also undertake work related to SEND conversion and QC for data creation and conversion only. Our facility was the first in Japan to obtain full accreditation from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International), and we are committed to international standards of animal welfare. We also propose tests necessary for various applications and registrations in compliance with regulations in different countries and regions.