Measurement of Drug Concentration in Biological Samples: Examination and Establishment of New Analytical Methods
We will establish a measurement method suitable for the target substance!
We will examine and establish measurement methods used in safety tests (TK) and pharmacokinetic tests (PK). Translation of measurement methods conducted at other facilities is also possible. 【Examination and Establishment of New Analytical Methods】 ■ Target: Test substances and their metabolites in biological samples such as blood, urine, feces, and tissue homogenates ■ Methods: Protein precipitation, solid-phase extraction, liquid-liquid extraction, etc. ■ Measurement conditions: LC-MS/MS and HPLC, etc. *For more details, please refer to the PDF document or feel free to contact us.
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Our company is located in the nature-rich city of Ina, Nagano Prefecture, surrounded by two Alps, and has been serving our customers as a non-clinical trial contract research organization (CRO) for 50 years. Since 2022, we have become a member of the Shin Nippon Science Group, expanding and enhancing our contract testing items and analyses, and we can quickly respond to the procurement of various testing materials (such as animals). Non-Clinical Trial Business We accept safety and efficacy testing for pharmaceuticals, chemicals, pesticides, food, medical devices, and more. We conduct in vivo tests using small animals, rabbits, dogs, and monkeys, as well as in vitro tests using bacteria and cells, and various alternative method tests. Additionally, we specialize in the creation of SEND data required for FDA applications for new drugs, and we also undertake work related to SEND conversion and QC for data creation and conversion only. Our facility was the first in Japan to obtain full accreditation from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International), and we are committed to international standards of animal welfare. We also propose tests necessary for various applications and registrations in compliance with regulations in different countries and regions.