It can be used for affinity purification of the noteworthy VHH antibodies.
Our protein A resin enables the affinity purification of VHH antibodies derived from camelids.
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basic information
VHH antibodies derived from camelids have recently attracted attention for their high stability and ease of protein engineering modifications. However, since there are no affinity ligands specific to VHH antibodies, it is mostly the case that tags are added for purification purposes. Meanwhile, it has been reported that Protein A can bind not only to the Fc region of IgG but also to the VH region. Utilizing this characteristic, we examined whether VHH antibodies could be purified using our Protein A resin product, Bipo Resin Protein A (Alkaline Resistance) (Code: AAR-025).
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Purification of VHH antibodies
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■Construction of protein expression plasmids and protein expression/purification ■Manufacturing and sales of non-natural amino acid incorporation protein synthesis reagents (CloverDirect series) and E. coli cell-free translation kits (RYTS Kit) ■Sales of affinity ligands and affinity resins for antibody purification ■Sales of anti-KIAA polyclonal antibodies
![Purification of IgA and IgM [Example]](https://image.mono.ipros.com/public/product/image/9ac/2000365840/IPROS3695842705784693035.png?w=280&h=280)