A biomarker that captures the early stages of lipid peroxidation! Quantification of hexanoyl lysine adducts is possible.
This product is expected to serve as a new oxidative stress biomarker that can capture the early stages of lipid peroxidation, unlike conventional aldehyde-based lipid peroxidation markers such as 4-HNE (4-hydroxy-2-nonenal) and MDA (malondialdehyde). Regarding its association with diseases, it has been immunologically proven to localize in human atherosclerotic lesions, and the generation of HEL in muscle in a rat exercise model, as well as the inhibitory effects of flavonoids on its production, have been clarified. 【Features】 ■ Simple quantification of hexanoyl lysine adducts in biological samples ■ Usable for research and evaluation of oxidative stress in vivo, particularly in the early stages of lipid peroxidation ■ Capable of assessing lipid-related oxidative stress in various samples such as urine, serum, and cultured cells *For more details, please refer to the PDF document or feel free to contact us.
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【Specifications】 ■Measurement Principle: Competitive ELISA method using anti-hexanoyl lysine antibody ■Measurement Range: 2 to 700 nmol/L ■Time Required: Overnight + 2 hours ■Number of Tests: 54 tests (18 samples when measured in triplicate), can be used in split ■Required Equipment ・Microplate reader (measurement wavelength 450nm) ・Low-temperature incubator (4 to 7℃) ・8-channel micropipette (50 to 250μL) ・Tray ・Micropipette (for 10 to 50μL), etc. ■Storage Conditions: Refrigerated (shelf life is 2 years from the date of manufacture) *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Nikken Zail Co., Ltd. is a company that provides research reagents in a wide range of fields, including medicine, pharmacy, biochemistry, and food. Among them, the Japan Institute of Aging Control develops, manufactures, and sells research reagents in areas such as anti-aging, and also conducts contract testing. We will continue to enhance our research and development and production technology, while providing new products and services to contribute to the health of people around the world.