Is it visual observation of the beating of cultured cardiomyocytes? No pretreatment! Just place it! Real-time automatic detection even in multi-well plates.
By simply placing the culture plate on this device, the heart rate and contraction time of cultured cardiomyocytes can be measured non-invasively and without staining. The measurement results are displayed in real-time as waveforms, and the number of beats and contraction time are automatically detected with the push of a button. It has built-in temperature control and a plate movement mechanism. Compact and lightweight, it is ideal for personal use. Please use it for examining the culture conditions of cardiomyocytes or for preliminary tests of cardiotoxicity assays for compounds.
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basic information
**Structure of CIOS8** - The main unit incorporates a light source, light receiving section, signal processing circuit, and temperature control stage all in one. - Electric well plate carrier The plate moves left and right, measuring 96 wells with 4 simultaneous measurements across 3 rows. Cardiac cell activity can be measured under stable conditions without opening the lid. **Options** - Simple membrane potential measurement using membrane potential-sensitive dyes. **Main Specifications** Compatible culture plates: Culture plates sized 96 wells or smaller Culture plate movement mechanism: Electric Temperature control: Automatic Detection items: Heart rate, contraction time Control PC: Recommended Windows 7/10 64-bit Dimensions: Width 185mm x Depth 115mm x Height 75mm Weight: Approximately 1kg
Price range
P5
Delivery Time
Applications/Examples of results
～ Application Examples ～ - Measurement of beating in cultured cardiomyocytes - Confirmation of differentiation of iPS-derived cardiomyocytes - Evaluation of cardiotoxicity of new drug candidates - Simple measurement of membrane potential using membrane potential-sensitive dyes
Detailed information
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Light source section The sample is brightly illuminated by a light-emitting diode placed on the underside of the sample.
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When the upper cover is opened, place the multi-well plate on the CIOS8.
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Overall view A lid is placed on top. The well plate moves left and right due to the electric carrier. A total of 96 wells are measured with 4 simultaneous measurements across 3 rows. The activity of cardiac cells can be measured under stable conditions without opening the lid.
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Control software can display and analyze recorded waveforms.
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Data example After acquiring the data, the number of beats and contraction time are automatically detected with a button click.
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Company information
After developing a high-speed imaging device necessary for neuroscience research, Brain Vision was established in May 1998 as an official venture of RIKEN with the aim of commercializing various ideas that emerged during neuroscience research. To date, over 100 high-speed imaging devices have contributed to advanced research activities at major neuroscience and cardiac research institutions around the world. In recent years, it has also been highly regarded in the field of optoelectronics and has already contributed to research and development at related research institutions and liquid crystal manufacturers. Further contributions in various industrial fields are expected in the future. Brain Vision aims to provide innovative technologies born from neuroscience research to the market and contribute to the advancement of science and industry.