It is a technology that heats and melts the raw materials using a twin-screw and a precisely temperature-controlled barrel to extrude solid dispersions.
This is a technology that extrudes and molds solid dispersions of raw materials using a dual-axis screw and a precisely temperature-controlled barrel. It particularly improves the dissolution of poorly water-soluble drugs by preparing solid dispersions with various polymers and excipients in the pharmaceutical field. Additionally, applications such as sustained-release formulations and taste masking are also possible.
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basic information
【Features】 - The screw has a modular design, allowing for processing with the optimal combination for formulations and purposes. - The barrel also has a modular design, enabling precise temperature control for each barrel, allowing for optimization according to the formulation. - It is possible to provide a system that integrates raw material supply, pre-mixing, and post-processing such as grinding and pelletizing. - Continuous processing is possible. - It is possible to prepare very uniform solid dispersions. - It can accommodate everything from small research machines to large production machines. - Solid dispersions can be prepared without the use of solvents.
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Applications/Examples of results
【Application Examples】 Improvement of dissolution of poorly water-soluble drugs Preparation of sustained-release formulations Bitter taste masking
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The words that are often spoken within our company are "grasp change and create change," and "contribute to the irreplaceable Earth, which is home to humanity and many species, with our unique technology." We also pass down the aspiration to become a company welcomed worldwide. To realize this, each individual at NARA must broaden their perspectives and hearts, actively participate in their own transformation, and at the same time, maintain a firm commitment to uphold their originality in the face of valuable challenges. Although we are still inexperienced, we intend to take steps toward NARA's ideals, with the broad support and guidance of everyone, and sometimes even receiving admonishments, as we move forward.