Research on the relationship between various diseases and macrophages! Liposomes suitable for macrophage phagocytosis.
"Clodronate-encapsulated liposomes" are suitable for research related to various diseases and macrophages. Clodronate as a standalone agent is not easily permeable through cell membranes, and its uptake efficiency by macrophages through phagocytosis is also low. By encapsulating clodronate in liposomes, it is possible to promote phagocytosis by macrophages, making it useful for macrophage depletion experiments. [Features] - Suitable for research related to various diseases and macrophages - Encapsulating clodronate in liposomes can promote phagocytosis by macrophages - Usable for macrophage depletion experiments *For more details, please refer to the PDF document or feel free to contact us.
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basic information
【What is Clodronate?】 - Inhibits ATP metabolism as an ATP analog within cells. - Used as a treatment for osteoporosis by inhibiting bone resorption through the depletion of osteoclasts. - Gaining attention as an effective formulation in fields such as multiple myeloma and bone metastatic cancer. - Has the effect of depleting macrophages. *For more details, please refer to the PDF document or feel free to contact us.
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【Purpose】 ■By administering to animals, it depletes macrophages in the liver and spleen. *For more details, please refer to the PDF document or feel free to contact us.*
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At Katayama Chemical Industry Co., Ltd., we mainly engage in the manufacturing and sales of reagents, chemical products, specialty synthetic chemicals, and pharmaceutical raw materials. In addition to our own developed products, we quickly provide a variety of reagents, equipment, and consumables from various manufacturers both domestically and internationally. We also offer various contract services to support our customers' research activities in multiple ways.