Contract for the production of genetically modified mice: Knock-in mouse production

We propose a suitable plan! This is a contract that requires advanced technology for the production of genetically modified mice.

We are engaged in the production of "knock-in mice." Knock-in refers to a method of introducing foreign genes into the mouse genome and analyzing the function of the introduced gene products. It is possible to design the insertion of foreign genes in such a way that endogenous genes are simultaneously disrupted, to design inducible expression using the Cre/loxP system, and to achieve simultaneous expression of multiple foreign genes. The insertion of reporter genes (such as LacZ, GFP, etc.) to investigate the activity of gene expression control regions in the genome also falls under the production of knock-in mice. The gene-modified mouse production we conduct requires advanced technology. 【Features】 ■ Insertion of foreign genes into the mouse genome ■ Simultaneous disruption of endogenous genes is also possible (knock-in and knockout) ■ Expression of reporter proteins can be controlled by endogenous regulatory regions ■ Inducible expression using the Cre/loxP system is also possible ■ Insertion of desired genes at desired locations in the genome at the nucleotide level *For more details, please refer to the PDF materials or feel free to contact us.

Animal cells