Conditional knockout has become a very useful method for analyzing gene function.
Our company is engaged in the production of "conditional knockout mice." Conditional knockout, also known as condition-specific gene disruption, is a method that involves creating mice with a gene locus flanked by the Cre recombinase target sequence loxP, which targets a specific gene region. By crossing these mice with mice that express Cre recombinase in a tissue- and time-specific manner, we can induce the disruption of the target gene only in specific tissues and at specific times. In recent years, various Cre-expressing mice have been developed, including those that induce activity through drugs (such as CreER), making conditional knockout a very useful method for analyzing gene function. 【Features】 - Possesses loxP sequences, allowing gene disruption through the expression of Cre recombinase. - Enables the analysis of lethal genes. - Allows for tissue-specific gene disruption. - Enables time-specific gene disruption. - We also accept the production of mice from targeting vectors from KOMP and EUCOMM. *For more details, please refer to the PDF materials or feel free to contact us.
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【Service Flow】 (1) Meeting regarding the creation of genetically modified mice (2) Formal contract (3) Construction of homologous recombination vector for gene modification (4) Establishment of recombinant ES cells from gene introduction (5) Creation of mice from established recombinant ES cells (6) Delivery *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Our company is engaged in the production of gene knockout mice, providing genetic information to research institutions such as universities and pharmaceutical companies, selling reagents, and conducting non-clinical and clinical trial contracts, as well as pathological diagnosis. Through the development of biological resources from individual organisms to genomes, we provide genetic information for foundational research and in the fields of medicine and healthcare. Please leave the production and sale of knockout mice, gene knockout mice, and antibodies to us.