Cosmetic ingredients: natural polysaccharides for anti-wrinkle and UV care, Schizophyllan.
Suppression of redness, wrinkle improvement, enhancement of NMF, improvement of moisture retention, regulation of immune processes, natural polysaccharides, ECOCERT.
Schizophyllan is a water-soluble high molecular weight polysaccharide produced in the cell walls of the fungus Schizophyllum commune. It can regulate various types of cellular responses to external stimuli and influence cell survival rates and protein synthesis. Skin aging caused by UV stress can lead to a deterioration of immune processes, resulting in the formation of wrinkles and dehydration. Schizophyllan has been confirmed to improve skin moisture levels and reduce wrinkles by regulating the underlying immune processes. <Efficacy> =In Vitro= Improvement in cell survival rate: 40% increase Promotion of TGF-β production: 150% increase Enhancement of IL-6 production: 60% increase Enhancement of IL-1beta production: 20% increase Inhibition of MMP1 expression (UV irradiation): 40% inhibition =In Vivo= Barrier function recovery effect Increase in skin moisture levels Suppression of skin erythema Improvement of crow's feet wrinkles
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basic information
Schizophyllan is a water-soluble high molecular weight polysaccharide produced in the cell walls of the fungus Schizophyllum commune. It can regulate various types of cellular responses to external stimuli and influence cell survival rates and protein synthesis. Skin aging caused by UV stress can lead to a deterioration of immune processes, resulting in the formation of wrinkles and dehydration. Schizophyllan has been confirmed to improve skin moisture levels and reduce wrinkles by regulating the underlying immune processes. <Efficacy> =In Vitro= Increase in cell survival rate: 40% increase Promotion of TGF-β production: 150% increase Increase in IL-6 production: 60% increase Increase in IL-1beta production: 20% increase Inhibition of MMP1 expression (UV irradiation): 40% inhibition =In Vivo= Barrier function recovery effect Increase in skin moisture levels Suppression of skin erythema Improvement of crow's feet wrinkles
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Applications/Examples of results
This product is water-soluble and can be adapted to various formulations. (Note: It does not dissolve well in formulations containing 40% or more alcohol.) - Day creams 0.05 - 0.10% - Night creams 0.02 – 0.10% - Eye creams 0.02 – 0.10% - Serum 0.05 – 0.20% - Cleansing gels 0.01 – 0.05% - Body lotions 0.05 – 0.10% - Sunscreen cream/milk 0.10 – 0.20% - After sun milk 0.005 – 0.05%
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Company information
Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.