Three-dimensional cultured human skin model 'LSE-high'

Morphologically and biochemically similar to human skin! A full-layer skin model with epidermis and dermis!

"LSE-high" is a three-dimensional cultured human skin model that has a structure similar to human skin and shows a high correlation with human skin in terms of skin barrier function. It can be used as a research and development tool in place of animal skin or human skin. Developed with a focus on "skin barrier function," it is suitable for various skin evaluations, including the skin permeability of active ingredients in cosmetic ingredients, quasi-drugs, or pharmaceuticals (topical agents). 【Features】 ■ Composed of two layers: dermis and epidermis ■ Has a layered structure that can be morphologically distinguished ■ Immunostaining with epidermal differentiation markers showed a distribution comparable to that of living skin ■ The lipid composition (such as ceramides) is very similar to that of human skin ■ Produces various physiologically active substances in response to drug stimulation, etc. *For more details, please download the PDF or feel free to contact us.

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