Nano-liter dispenser mosquito LCP for membrane protein crystallization
mosquito LCP
The standard model of the crystallization robot, mosquito, has been enhanced with the functionality for membrane protein crystallization!
The mosquito LCP is a nanoliter dispensing machine for membrane protein crystallization, equipped with a dedicated dispensing head for the LCP crystallization method, in addition to the functions of the Xtal3 model. It allows for the miniaturization of rare protein sample amounts and enables reproducible high-throughput experiments. We also offer a precision humidification chamber (optional) to mitigate the effects of drying in miniaturized experiments. This is a mosquito-specific chamber that controls the humidity around the dispensing deck. The LCP model comes in two types: a 2-way type that can accommodate two crystallization plates and a 4-way type that can accommodate four plates. In cases where you want to use the mosquito for purposes other than crystallization, we may recommend the 4-way type. For more details, please contact us.
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basic information
< Model: LCP 2-way | LCP 4-way > ■ Model Number: 3072-01030 | 3072-01031 ■ Plate Installation Count: 2 plates | 4 plates (XYZ control 0.05mm) ■ Reservoir Installation Count: 8-channel reservoir x 1 location | Using dedicated block ■ Weight: Approximately 32kg | Approximately 34kg ■ Main Body Size (mm): W450 × D590 × H690 | W790 × D590 × H690 < Dispensing Performance: mosquito chip | LCP dispensing head > ■ Dispensing Channel Count: 8 or 16 channels | 1 channel ■ Dispensing Volume: 25 - 1200 nL (minimum dispensing amount: 10 nL) | 25 nL – 100 μL ■ Dispensing Resolution: 1 nL unit ■ Dispensing Accuracy (CV value): < 8% (50nl), < 7% (100nl) | < 10% (25 nL) ■ Throughput: < 2 minutes / 96 drops, approximately 5 minutes / 96 LCP drops ■ Compatible Syringe (LCP dispensing head): 50μL, 100μL Hamilton gas-tight glass syringe (commercially available)
Price information
Please contact us.
Price range
P7
Delivery Time
※The average delivery time is 2 to 3 months.
Applications/Examples of results
【Protein Crystallization Field】 □ Sitting Drop Method □ Hanging Drop Method □ Additive Screening □ Microseeding □ Microbatch Method □ Viscosity Method □ LCP Method
Detailed information
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This chip, which adopts a positive displacement method, can accurately dispense not only high-viscosity and highly volatile solutions but also foaming solutions. It is made of stainless steel and HDPE, and can also dispense DMSO.
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On channel 8, we will perform dispensing by row. All crystallization methods that can be executed with mosquito Xtal3 can be conducted using the LCP model.
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It is possible to complete the creation of LCP crystal drops in 96 wells in less than 5 minutes by dispensing a lipid solution with a gastight syringe and further dispensing the precipitant with a disposable positive displacement tip from a mosquito.
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The protocol can be easily designed to match the wizard.
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[Option] Precision Humidification Chamber: In nano-litter scale micro-dispensing, the effects of drying cannot be ignored. The chamber surrounding the mosquito plate deck maintains an appropriate humidity environment.
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[Option] Benchtop LCP Mixer Unit: It can set two connected gas-tight syringes (100μL or 50μL) to automatically mix LCP samples.
Line up（2）
| Model number | overview |
|---|---|
| LCP | Capacity: 25-1200nL, Number of channels: 8 or 16, Dedicated software for protein crystallization + Lipid Cubic Phase method |
| Xtal3 | Capacity: 25-1200nL, Number of channels: 8, Dedicated software for protein crystallization |
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Company information
We aim to embed our unique technology and deep understanding of applications into each product, providing researchers with new options to accelerate their research. In addition to user-friendly specifications and highly robust systems, the establishment of our Japan branch has enabled us to offer rapid engineering support. We specialize in applications that require nanoliter-scale dispensing, reducing sample and time costs: - Miniaturization/automation of various assays - Miniaturization/automation of PCR, qPCR, and NGS library preparation in the genomics field - Miniaturization/automation in the field of protein crystallization - Automated management of sample vials We have experienced representatives and dedicated application staff in the country. We look forward to your inquiries and demo requests.
