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  6. [Data] Antibacterial effects of Polylysine in various pH ranges.

[Data] Antibacterial effects of Polylysine in various pH ranges.

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Polylysine

last updated:Jul 16, 2025

JNC
JNC
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Natural amino acid "Polylysine" as an additive in food preservatives, hygiene materials, and daily necessities. Introducing the antibacterial effects of polylisine in various pH ranges.

ε-Polylysine (hereinafter referred to as Polylysine) is a substance formally known as ε-Poly-L-lysine. It is a homopolymer consisting of 25 to 35 units linked by amide bonds, formed from the ε-amino group of the essential amino acid L-lysine and the α-carboxyl group. Since 1989, it has over 30 years of manufacturing experience and is widely used as a preservative in food. We present the minimum inhibitory concentration (MIC) of Polylysine in combination with sorbic acid, acetic acid, and glycine at pH 5 to 9. Polylysine exhibits stable antibacterial effects at low concentrations across a wide pH range from weakly acidic to weakly alkaline. Many foods we consume have a pH close to weakly acidic to neutral. Polylysine, which shows stable antibacterial effects in small amounts across a wide pH range, can be suitably utilized in various foods. *For more details, please download the PDF or feel free to contact us.

    Shelf life enhancer
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[Data] Antibacterial effects of Polylysine in various pH ranges.

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**Characteristics of Polylysine** - Exhibits excellent antibacterial effects against various microorganisms in small amounts. - Shows antibacterial effects over a wide pH range. - Has excellent thermal stability. - Demonstrates synergistic effects when used in combination with chelating agents. - Has a rich track record of use as an additive in cosmetics, hygiene materials, and daily necessities. - Possesses excellent properties as a preservative with high safety. - Highly soluble in water, making it easy to use in food. - Exhibits excellent growth inhibition effects against a wide range of microorganisms, including gram-positive bacteria (such as Bacillus cereus), gram-negative bacteria (such as Escherichia coli), and yeasts, particularly those causing food poisoning. - Also shows excellent growth inhibition effects against heat-resistant bacteria, including Bacillus subtilis. - Exhibits strong inhibitory effects against lactic acid bacteria, which significantly affect food spoilage. - High safety has been confirmed through acute toxicity, subacute toxicity, chronic toxicity, mutagenicity, and pharmacokinetic tests in accordance with the guidelines of the Ministry of Health, Labour and Welfare. *For more details, please download the PDF or feel free to contact us.*

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25% Aqueous Solution Aqueous solution containing 25% Polylysine
50% Powder Powder consisting of 50% Polylysine and 50% dextrin

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Our group was founded in 1906 as Sogi Electric Co., Ltd., and since then, we have been a pioneer in Japan's chemical industry, contributing to the development of society by expanding renewable energy generated by hydropower into the field of electrochemistry and developing domestic nitrogen fertilizers. Our unchanging mission is to engage in manufacturing that harmonizes with the global environment, to solve our customers' challenges in order to realize a rich life, and to cultivate outstanding human resources who can thrive globally, continuously serving society.

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