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  6. Cosmetic ingredients for sensitive skin, microbiome-regulating anti-exposome.

Cosmetic ingredients for sensitive skin, microbiome-regulating anti-exposome.

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last updated:Oct 24, 2025

HIGUCHI INC.
HIGUCHI INC.
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Skin microbiome adjustment for sensitive skin, pain suppression, TRPV-1 inhibition, suppression of bacteria causing redness, erythema suppression, anti-wrinkle, anti-exposome.

Today, it is said that 50% of women in Europe, America, and Japan have sensitive skin. Regardless of the presence of erythema, sensitive skin experiences excessive reactions to environmental factors, accompanied by sensations such as stinging and itching. These factors can be external (such as UV rays and chemicals) or internal (such as stress and hormones), and in most cases, they cause discomfort to the skin and visible symptoms. Additionally, it is believed that skin microbiota are involved in the symptoms of sensitive skin. In response to this significant challenge, GREENTECH has developed a functional product, ExpoZen, to protect the skin from harmful exposomes. In Vitro: Effects on inflammation and neurogenic inflammation suppression: - TRPV-1: -67% - TNF-α: -21% - NK1-R: -43% - VEGF: -16% Effects on barrier function improvement: - Increased epidermal thickness: +12% In Vivo: Microbiome regulation: - Suppression of bacteria associated with inflammation and redness (C. Kroppenstedtii) - Increase of beneficial bacteria (S. epidermis) Improvement of sensitive skin symptoms: - Skin irritation: -34% - Pain: -33% - Tingling: -40% - Erythema: -24%

    Cosmetic materials and raw materialsOther pharmaceutical intermediates and cosmetic ingredientsOther medical supplies and cosmetic manufacturing materials
EXPOZEN表紙_page-0001.jpg

Cosmetic ingredients for sensitive skin, microbiome-regulating anti-exposome.

EXPOZEN表紙_page-0001.jpg
EXPOZEN表紙_page-0001.jpg
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Green Tech Co., Ltd. is a company established in 1992. The company has been importing and selling various types of plant extracts in Japan for about 20 years, and we have heard that Japanese customers perceive Green Tech as a manufacturer with a wide range of plant extracts. In fact, the company handles over 5,000 types of plant extracts. In addition to traditional plant extracts, we also manufacture and sell products that focus on the biodiversity of South America, particularly Brazil, including plant extracts and oils, as well as products developed based on microbiological research that demonstrate effectiveness in maintaining microbial community stability. We also produce components and extracted extracts derived from algae and microalgae. In recent years, we have been focusing on research and development, not only enhancing the evaluation data for our products in In-Vivo and In-Vitro studies but also conducting research and development in response to new trends such as skin microbiomes. Additionally, we are committed to the development and manufacturing of products that have demonstrated effectiveness by increasing the concentration of active ingredients using our proprietary freeze technology (preservation, grinding, extraction) and fermentation technology. These manufacturing technologies are not only applicable to the development of our own products but also support the development of customized products.

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Applications/Examples of results

Recommended usage amount: 3% Recommended usage pH: 4.0~6.0 Cold process use is recommended. Applications: ■ Products for sensitive skin ■ Urban skincare products ■ Daily skincare products ■ Anti-aging products ■ Baby care products ■ Improvement of skin microbiome diversity

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Cosmetic ingredients for fluctuating and sensitive skin, microbiome adjustment, anti-exposome, plant extracts, exposome.

Cosmetic ingredients for fluctuating and sensitive skin, microbiome adjustment, anti-exposome, plant extracts, exposome.

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Cosmetic ingredient for acne improvement for oily skin, microbiome fruit extract, Acnilys.

Cosmetic ingredient for acne improvement for oily skin, microbiome fruit extract, Acnilys.

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Cosmetic ingredient Active plankton extract Silidine (SILIDINE)

Cosmetic ingredient Active plankton extract Silidine (SILIDINE)

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Company information

HIGUCHI

HIGUCHI INC.

Trading company/Wholesale

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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.

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