High-pixel Direct Detection Device (DDD) camera!
Transmission electron microscopy (TEM) is a powerful technique for visualizing structures at nanometer or angstrom resolution. However, the performance of TEM lags significantly behind the theoretical limits based on the physics of electron scattering, especially when low-dose imaging is required. Multiple factors, including microscope equipment, dynamic sample processes (drift, beam-induced motion, charging, radiation damage, etc.), and inefficient electron detectors, contribute to the degradation of the resolution and signal-to-noise ratio (SNR) of TEM images. To overcome many of these obstacles, Direct Electron introduced the first large-pixel Direct Detection Device (DDD) in 2008. This represents the culmination of academic and industrial partnerships that have worked on sensor development over several generations since 2001. Direct Electron's innovative DDD sensor received the 2010 Microscopy Today Innovation Award.
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basic information
Conventional TEM digital cameras use a scintillator to convert primary electrons in the microscope into photons, which are then detected by an image sensor. In contrast, DDD directly detects the image-forming electrons in the microscope without using a scintillator. As a result, resolution, signal-to-noise ratio, and sensitivity are dramatically improved. The secret to DDD's high performance lies in its thin sensing layer. The incident beam electrons pass through this thin layer, leaving an ionization trail. The ionization trail is collected and integrated or counted on a pixel-by-pixel basis. Because the layer is very thin, lateral charge spreading is minimized, resulting in higher resolution than other detectors. Furthermore, DDD minimizes image distortion by directly detecting electrons without transferring signals through optical fibers or lenses. The second innovative feature of DDD is its high frame rate with no dead time between frames. This high frame rate provides inherent dose fractionation during image acquisition. This can be utilized for motion correction, damage correction, and other image processing techniques. High frame rate data acquisition also enables challenging TEM applications, such as in-situ TEM.
Price information
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Applications/Examples of results
Transmission Electron Microscope (TEM)
Detailed information
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[Modulation Transfer Function] The Modulation Transfer Function (MTF) is one of the most widely used scientific methods for describing optical performance. MTF measures contrast across all spatial frequencies. The DDD camera from Direct Electron has very high resolution and contrast, theoretically approaching or reaching its maximum value even as spatial frequency increases.
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【Detective Quantum Efficiency (DQE)】 In the case of TEM cameras, DQE measures the combined effect of the detector's signal performance and noise performance. The DQE curve can be considered with resolution on the X-axis and relative signal-to-noise ratio on the Y-axis, where higher results are better. The DE series demonstrates low noise and high resolution that are theoretically close to the maximum value in both counting mode and integration mode as the spatial frequency increases.
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Carbon Film Thon Ring The exceptional high-resolution performance of the DE series cameras from Direct Electron means that the camera is no longer a major limiting factor for TEM resolution. The DE-20 demonstrates very high-resolution bright field TEM imaging, and the Thon ring reaches a resolution of 2.3 angstroms (92% Nyquist).
Line up(3)
Model number | overview |
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DE-Direct View | This is a DDD camera with high sensitivity and high resolution, offering excellent cost-effectiveness in the fields of biology and materials science. |
DE-16 | This is a DDD camera with 6.5um pixels and 4K x 4K resolution, suitable for the most extensive range of applications. |
DE-64 | This is a DDD camera optimized for the world's first cryo-electron microscope, featuring true 8K x 8K resolution. |
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Tegasaience Co., Ltd. is a specialized trading company for scientific and analytical instruments, headquartered in Kitakashiwa, Kashiwa City, near Lake Tega, where wild birds gather. Founded at the beginning of the 21st century, we have been providing excellent scientific and analytical instruments and precision equipment from Europe and the United States to domestic research institutions. Moving forward, we will continue to strive to contribute to the development of Japan's science and technology, focusing on areas that cannot be covered by domestic products. The bird in Tegasaience Co., Ltd.'s trademark is a colorful arrangement of the Eurasian Coot, which is abundant in Lake Tega.