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  6. Microwave Peptide Synthesis Device Liberty PRIME 2.0

Microwave Peptide Synthesis Device Liberty PRIME 2.0

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last updated:Dec 09, 2022

CEM Japan
CEM Japan
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An updated version of the automatic microwave peptide synthesizer boasting unparalleled processing speed and efficiency.

Liberty PRIME 2.0 is the world's best peptide synthesizer currently available. Its unique one-pot deprotection/coupling synthesis method allows for an astonishingly short synthesis cycle of approximately 2.5 minutes and a minimal waste volume of only 8.5 mL per cycle (0.1mmol). Improved robustness from the previous generation enables the synthesis of high-purity long-chain peptides. Liberty PRIME 2.0 is a highly adaptable synthesizer ideal for the synthesis of long-chain peptides, difficult-to-synthesize peptides, and peptides with complex sequences. Furthermore, its ultra-fast continuous synthesis workflow provides efficiency far surpassing that of traditional parallel synthesizers. It can also be used for the synthesis of cGMP peptides.

    Other physicochemical equipment
Liberty

Microwave Peptide Synthesis Device Liberty PRIME 2.0

Liberty PRIME 2_withHT24 (small low).jpg
Liberty PRIME 2_withHT24 (small low).jpg
  • Related Link - https://cem.com/ja/liberty-prime-2

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basic information

- Size: 1250(W) x 500(D) x 750(H) mm - Weight: ~100 kg - Power supply: 100 VAC, 50/60 Hz, 10 A - Requires high-purity nitrogen (over 90%) or argon at approximately 350 kPa (minimum 50 psi, maximum 100 psi, 20 L/min) - CarboMAX-style coupling reaction (patented) - Deprotection and coupling by microwave (patented) - One-pot coupling/deprotection synthesis method (patented) - Headspace cleaning (patent pending) - Synthesis cycle of at least 2.5 minutes per amino acid (0.1 mmol) - Waste volume per cycle: 8.5 mL (0.1 mmol) - Accurate delivery of all reagents without calibration - Internal true temperature control via optical fiber - Synthesis scale of 0.005 to 5 mmol / nitrogen digital control - 30 amino acid positions - Integrated reaction vessel camera - High-throughput upgrade options (HT4, HT12, HT24) - Compatible with cGMP peptide production

Price range

P7

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Applications/Examples of results

Delivery Performance - Pharmaceutical Companies - Drug Discovery Ventures - Contract Synthesis Companies - Others

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CEM

CEM Japan

Testing, Analysis and Measurement

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CEM Corporation is a leading provider of microwave laboratory systems worldwide. Since 1978, we have offered a complete portfolio of award-winning equipment and industry-leading technology designed with CAD for the markets of analytical experimentation, synthetic chemistry, biosciences, and process management. In 2003, CEM launched a microwave peptide synthesis system, an automated system that produced peptides with higher purity and yield than any method available at the time. Since then, we have continued to design and develop new technologies and methods to improve peptide synthesis. CEM systems are used by Fortune 500 companies, renowned universities, and research institutions around the world. We believe that our responsibility to our customers does not end when the product is shipped; it truly begins at that moment.

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