Temperature-responsive cell culture equipment UpCell flask available for sample provision.
CSUF075 / CSUF175
It is possible to culture and recover a large number of cultured cells such as macrophages and immune system cells without damage and without using trypsin.
Celsheed Technology By utilizing a unique nano-surface design, temperature-responsive polymer (PIPAAm) has been immobilized on the surface of equipment. This allows the surface temperature to be lowered, causing the culture surface to change from hydrophobic (cell-adhesive) to hydrophilic (cell-releasing) at around 32°C, resulting in cell detachment. Without using any enzymes that can damage cells, such as trypsin, intact cells can be recovered simply by setting the equipment temperature to 20-25°C and waiting for about 10-30 minutes. ● This is the first large flask type UpCell developed for large-scale culture. ● Adhesive cells such as mesenchymal stem cells, dendritic cells, and macrophages can be recovered without trypsin treatment. ● The flask type minimizes the risk of contamination.
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basic information
- Product Name: UpCell T75 Flask Size (mm): 136.1 (L) × 81.0 (W) × 35.4 (H) Culture Area: 75cm × 75cm Cap: Filter Cap Packaging: 20 pieces/box (4 pieces/bag: single packaging) - Product Name: UpCell T175 Flask Size (mm): 227.0 (L) × 225.6 (L) × 46.5 (H) Culture Area: 175cm × 175cm Cap: Filter Cap Packaging: 4 pieces/box (1 piece/bag: single packaging)
Price information
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Delivery Time
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Applications/Examples of results
You can collect adhesive cells such as mesenchymal stem cells, dendritic cells, and macrophages.
Detailed information
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Launched in 2007, UpCell is a product that allows for the detachment of cells while maintaining their biological functions simply by lowering the temperature, without the need for proteases like trypsin or physical stimuli such as scrapers. This made it the world's first product capable of recovering cell sheets in a damage-free state. Currently, UpCell is sold worldwide, and many researchers are actively engaged in the research and development of therapies using cell sheets. ◆ UpCellⓇ Flask: By applying the unique UpCell processing technology for large-scale cell recovery from cell sheets to cell culture flasks, it is possible to recover cells over an area up to approximately three times larger compared to the conventional UpCell 10cm dish products. Using this UpCell flask, we can deliver large quantities of cells required for cell therapies involving macrophages, dendritic cells, and mesenchymal stem cells without any damage.
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Company information
CellSeed is committed to the belief that "we want to deliver the world's first cell sheet engineering-based treatment to patients around the world as soon as possible," and we are challenging ourselves every day. We will continue our efforts toward the commercialization of cell sheet regenerative medicine products.