RNA analysis HPLC column "RNASep Prep Column"
RNA-99-3810 / ADS Biotec
High-performance liquid chromatography (HPLC) columns available for research and development of mRNA.
The RNASep Prep column manufactured by ADS Biotec (formerly Transgenomic) in the United States is a column for RNA analysis using high-performance liquid chromatography (HPLC) that can also be used for the research and development of mRNA drugs and mRNA vaccines. The column beads are made from polymer beads, allowing for use over a wider pH range compared to columns with conventional silica beads. It is utilized by customers worldwide, primarily in Europe and the United States.
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basic information
The RNASep Prep column manufactured by ADS Biotec (formerly Transgenomic) is designed for RNA analysis using ion-pair reverse-phase HPLC. It utilizes non-porous beads made of alkylated polystyrene-divinylbenzene (PS-DVB). Because the column beads are non-porous, there is less risk of impurities remaining on the beads, allowing for higher precision purification. This product has a proven track record, having been cited in numerous papers in the mRNA field. It can be used in the research and development of mRNA vaccines and mRNA therapeutics. By using the column, you can remove double-stranded RNA, an impurity that arises during mRNA synthesis. The column can be used with various types of high-performance liquid chromatography (HPLC) equipment. By utilizing ADS Biotec's buffer A and buffer B, which contain triethylammonium acetate (TEAA) as the mobile phase, you can achieve high-precision separation. Additionally, by following the procedures outlined in the instruction manual and cleaning the column with ADS Biotec's cleaning solution D, you can reuse the column multiple times.
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Applications/Examples of results
Removal of double-stranded RNA, an impurity during mRNA synthesis RNA purification
Detailed information
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RNA-99-3810 Analysis Example
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Manufacturer: ADS Biotec Inc., USA
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ADS Biotec, Inc. (formerly Transgenomic, Inc.) has been manufacturing and selling HPLC columns and buffers for nucleic acid analysis for over 20 years. We provide products to customers around the world, primarily in Europe and the United States.
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Good conditions: Compatible with alkaline conditions Generally, silica beads do not support analysis under alkaline conditions. The column beads from ADS Biotec use polymers and are compatible with a pH range of 0-14. You can freely set conditions without worrying about the pH of the buffer.
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High performance, capable of analyzing and purifying up to 6,000 bases. The columns and buffers from ADS Biotec are compatible with both short-chain RNA and long-chain RNA, allowing for the analysis and purification of samples of various sizes.
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Company information
ADSTEC Corporation has been committed to customer-oriented principles since its establishment in 2002, focusing on two main businesses: the import and sale of image-related equipment, and the development and manufacturing of gene-related equipment. We take pride in having established a system that allows us to respond to our customers' needs in a detailed and speedy manner, expanding our business network both in Japan and overseas in this rapidly evolving field. In these two areas, we aspire to be a group of experts who can assist with projects, including customer proposals, and we are dedicated to enhancing our technical skills as well as investing in staff education to cultivate "human power." Moving forward, we will continue to assess the trends of the times and provide and develop products that truly match our customers' needs.