Since the recycling loop is unnecessary, it can be concentrated in a single pass!
Unlike conventional Tangential Flow Filtration (TFF), Cadence(TM) single-pass TFF allows for the concentration of target substances without recirculating them. This enables a reduction in the flow path (installation space) and can be used for unstable target substances that are prone to inactivation. Additionally, at the end of the concentration process, only a small amount of product remains in the module, which is characterized by a high product recovery rate. Compared to conventional systems, it is also easy to recover the product without dilution.
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basic information
【Features】 ■ Improved processing capacity and cost reduction in downstream processes ■ Over 95% high product recovery rate ■ Concentration of over 20 times is possible ■ A process that maximally accommodates products unstable to shear forces ■ Compact system ■ Easy installation and operation
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Applications/Examples of results
【Applications】 ■ Scale-down of process ■ Desalting of protein solutions ■ Purification and recovery of antibodies and recombinant proteins ■ Solution adjustment before and after column chromatography (concentration and desalting) *For more details, please refer to the catalog or feel free to contact us.
Company information
Cytiva and Pall Life Sciences have merged their businesses and will officially launch under the "Cytiva" brand on May 1, 2023. Under our mission of "Advancing therapies, faster," we will integrate both organizations and focus even more on supporting the development and manufacturing of better therapies for patients as a stronger global provider of technologies and services. The new Cytiva will offer a broader and deeper expertise and a rich lineup of products and services to better support various customers involved in research and the manufacturing and development of biopharmaceuticals, enabling them to deliver therapies to patients more quickly, from discovery to delivery. With a rich history spanning several hundred years, Pall Life Sciences and Cytiva, as part of the Danaher Group, will continue to unite to provide better services to our customers.