Constructing a basement membrane for the physiological environment to improve the success rate and effectiveness of cell culture!
The GelNest matrix is derived from mouse tumor tissue and contains extracellular matrix components such as laminin, type IV collagen, and heparan sulfate proteoglycans. These components support cell adhesion, differentiation, and proliferation, providing signals for these processes. Furthermore, it simulates the characteristics of the basement membrane in a physiological environment, enhancing the success rate and effectiveness of cell culture.
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basic information
In addition to matrix components, the GelNest matrix is rich in various growth factors. These growth factors promote cell differentiation, proliferation, and migration, mimicking the signaling pathways and interactions of cells in a physiological environment. The GelNest matrix has a wide range of applications, particularly in tissue engineering, cell culture, and research. It can be used for organoid culture, stem cell differentiation, angiogenesis, migration or invasion assays, and in vivo tumor studies.
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Applications/Examples of results
- 2D culture coating - Evaluation of cell migration and tumor invasion - Organoid culture, 3D cell culture - In vivo vascular formation - Differentiation of stem cells - Tumor formation in vivo
Detailed information
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Applications of GelNest
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Proliferation of human cholangiocyte-like organoids after 5 days in competitor's matrix gel and GelNest matrix.
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Proliferation of human cholangiocarcinoma-like organoids after 6 days in competitor's matrix gel and GelNest matrix.
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Results of endothelial cells forming vascular networks after 9 hours of culture on competitor's matrix gel and GelNest matrix.
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Results of vascular network formation of HT-1080 cells cultured on the surface of competitive company matrix gels and GelNest matrix gels after 9 hours. It was suggested that FBS significantly induces cells to pass through the semipermeable membrane of the extracellular matrix and enter beneath the insert.
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GelNest Matrix Selection Guide
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Company information
With the expansion of our business, NEST products are sold in countries around the world, including North America, Europe, Japan, South Korea, and India, and we have built deep cooperative relationships with overseas customers. To deliver products to our overseas customers more quickly, we established NEST's U.S. branch in New Jersey in 2013. Our products are suitable for various fields of life technology, including medicine, agriculture, light chemical industry, food, environmental conservation, bioenergy, marine biological resources, and regenerative medicine, meeting a wide range of customer needs. Additionally, compared to imported consumables, our products have shorter delivery times, superior quality, and lower prices, significantly improving work efficiency and reducing utilization costs.