Achieving a wide dynamic range and analytical depth in quantitative proteomics of cells and tissues!
The "timsTOF HT" is a mass spectrometer (TIMS-QTOF) equipped with the fourth generation TIMS-XR and advanced digitizer technology. It achieves a wide dynamic range and analytical depth in quantitative proteomics of cells and tissues. Its unique device design enables robust performance and routine operation for thousands of samples without the need for cleaning. Additionally, ion mobility separation has been added to the quadrupole time-of-flight mass spectrometer. 【Features】 ■ Expands the possibilities of high-throughput 4D-Proteomics ■ Achieves a sequencing speed of 150 Hz ■ Improves analytical depth with the high charge capacity of the fourth generation TIMS-XR ■ TIMS-based ion mobility separation and CCS-compatible analysis ■ New features of PaSER maximize identification depth and throughput
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basic information
【Other Features】 ■Rapid tissue proteome analysis achieved with dia-PASEF ■Quantification of over 550 proteins with a 30-minute gradient ■High-level results achieved even with high-concentration samples using nano LC columns *For more details, please refer to the PDF document or feel free to contact us (Email: Mailnews.BDAL.JP@bruker.com).
Applications/Examples of results
【Application】 ■Quantitative Proteomics
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timsTOF HT
Company information
Bruker Bioscience Corporation, Bruker Daltonics Inc. is a leading manufacturer and seller of innovative mass spectrometry-based life science tools. We design, manufacture, and sell a wide range of products to meet the rapidly expanding needs of a diverse customer base, including universities, independent administrative research institutions, pharmaceuticals, food and beverage industries, and private companies engaged in contract research. The Daltonics division has a variety of technological foundations that integrate mass spectrometry systems such as MALDI-TOF, MALDI-TOF/TOF, MALDI microbial identification, (Q-q-) FTMS, ESI ion trap, ESI-LC/TOF, ESI-QTOF, surface plasmon resonance, GC MS/MS, along with automated sample preparation systems and software for life science applications.