A state-of-the-art super-resolution ultrasound imaging device for small animals that achieves both deep observation depth and high temporal resolution, allowing for clear imaging of microvessels at the micron level.
A state-of-the-art ultrasound imaging device that achieves deep observation depth and high temporal resolution, capable of mapping down to micron-level capillaries. When used in conjunction with ultrasound contrast agents (microbubbles), it achieves spatial resolution below 10 microns, enabling measurements of capillary distribution and blood flow velocity not only in the deep brain of rats and mice but also in the spinal cord, kidneys, liver, and tumors. This advanced ultrasound echo device is equipped with a variety of measurement functions suitable for observing mouse heart function and can be optimally utilized for various research topics, including tumors, neurological diseases, vascular issues, vascular plaques, coronary systems, kidney diseases, cellular drug research, brain function, and drug efficacy evaluation.
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basic information
[Measurement Items] Measurement of various cardiac functions in small animals, microvascular density, vessel diameter, vessel distance, blood flow velocity, blood flow volume, and vessel curvature, etc.
Price range
P9
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Applications/Examples of results
Examples of the application of super-resolution ultrasound imaging technology have been reported in the following papers: 1: In Alzheimer model mice, abnormalities in blood flow in microvessels occur before structural brain abnormalities are observed. 2: In the brains of aged mice, there is a decrease in blood flow velocity and an increase in vascular curvature, leading to a reduction in blood flow in the cerebral cortex. 3: Blood flow dynamics in the rat spinal cord respond specifically to stimuli. 4: In solid tumor model experiments, changes in microvessels due to cancer treatment can be visualized. For more details, please refer to the following papers: PMCID: PMC10904092, PMCID: PMC8755738, PMCID: PMC9352591, PMCID: PMC7977620, PMCID: PMC7015937, PMCID: PMC9014806 Please consider the introduction of "super-resolution ultrasound imaging in small animals," which is already expanding in research settings in Europe and the United States.
Detailed information
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VINNO 9LAB
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| Model number | overview |
|---|---|
| ULTIMUS 9 LAB | The latest small animal super-resolution ultrasound imaging device that achieves both deep observation depth and high temporal resolution, capable of vividly imaging microvessels at the micron level. This single device can be utilized in various fields of research, including measuring various functions of small animal hearts, mapping microvessels and measuring blood flow, assessing the effects of cancer treatment, and observing changes in blood flow in renal microvessels, thus promising new research results and improved research accuracy. |
| VINNO 6 LAB | A long-awaited small animal ultrasound imaging system that can vividly image mouse hearts and measure various functions, solving various issues in conventional research settings. Despite its compact size and space-saving design, it offers more than sufficient measurement capabilities and spatiotemporal resolution, eliminating dissatisfaction with traditional ultrasound echoes and enhancing research accuracy through high-precision heart function measurements. |
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Company information
After developing a high-speed imaging device necessary for neuroscience research, Brain Vision was established in May 1998 as an official venture of RIKEN with the aim of commercializing various ideas that emerged during neuroscience research. To date, over 100 high-speed imaging devices have contributed to advanced research activities at major neuroscience and cardiac research institutions around the world. In recent years, it has also been highly regarded in the field of optoelectronics and has already contributed to research and development at related research institutions and liquid crystal manufacturers. Further contributions in various industrial fields are expected in the future. Brain Vision aims to provide innovative technologies born from neuroscience research to the market and contribute to the advancement of science and industry.