Endotoxin-reducing chitosan should be considered for research purposes when researching and developing chitosan for medical applications.
Chitosan has a property that allows it to easily adsorb endotoxins, which can cause fever when they enter the bloodstream. When using chitosan in pharmaceuticals or medical devices, it is necessary to reduce and manage endotoxins. With our endotoxin reduction processing technology, we can treat various types of our chitosan products to reduce endotoxins and provide them to you.
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basic information
- We are capable of performing endotoxin reduction treatments on various types of chitosan products (ranging from low molecular weight to high molecular weight, including Koyo Chitosan FL-80, FM-80, FH-80, etc.). - We have developed extraction conditions that allow for good quantification of endotoxins in chitosan. - The quantification of endotoxins in chitosan is measured in accordance with the "Endotoxin Test Method" of the 18th Revision of the Japanese Pharmacopoeia, and under the developed extraction conditions, the reaction interference factor test (standard addition recovery) was determined to have no reaction interference factors, suggesting good quantification values. - Endotoxins in chitosan have been reduced to less than 0.1 EU/mg.
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Medical devices using chitosan
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Company information
Koyou Chemical Co., Ltd. mainly manufactures chitin, chitosan, glucosamine, N-acetylglucosamine, and their oligosaccharides, which are found in crustaceans. We are engaged in functional research and development of various materials that support "healthy and comfortable living" in collaboration with public research institutions and universities. Additionally, we propose and plan products made from "Sakaiminato quality" materials across a wide range of fields, including not only food but also industrial, agricultural, and cosmetic applications. Our company will continue to strive as a unified organization across manufacturing, research and development, sales, and product planning to provide products that meet your needs. If you have any inquiries related to chitin, please feel free to consult us.