Low pH flow-through virus inactivation for integrated continuous biopharmaceutical manufacturing.
Pionic Spin offers innovative advancements in the virus inactivation process in downstream bioprocessing. This device consists of an incubator, a recirculation loop, a 3D biocontainer, and a flow kit. All parts in contact with the liquid are single-use. The autonomous and sterile closed system operation of Pionic Spin simplifies the low pH virus inactivation process, providing unparalleled flexibility and control from clinical manufacturing to commercial production. *For more details, please click on "PDF Download" below. *If you would like a demo, please contact us through "Inquire About the Product" below.
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basic information
Features and Benefits ▪ Integration into existing equipment is possible. ▪ The flow rate during low pH treatment (incubation) can be adjusted (1 ~ 22 L/h), providing scalability. ▪ Continuous operation for 28 days is possible through the automation of inflow pH titration. ▪ Inflow inactivation of enveloped viruses exceeding 5 LRV is possible. ▪ A flexible biocontainer that achieves consistent outflow from variable injection flow rates.
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Company information
Sartorius Stedim, established in 2007 through the merger of the German company Sartorius, founded in 1870, and the French company Stedim, is a pioneer in "Single-Use Technology (SUT)." As a company capable of providing comprehensive technical support to the pharmaceutical and biotechnology industries, its cutting-edge technology is highly regarded worldwide in the fields of scientific instruments and biotechnology.
