Nanoindenter: Measuring the mechanical properties and mechanical behavior of biomaterials.
Optics11 Life's CHIARO
Chiaro is an ideal nanoindentation device for exploring the micromechanical properties of various biomaterials.
The Chiaro nanoindenter gently presses a spherical glass chip against the surface of a sample using a sensor, similar to an atomic force microscope (AFM). By meticulously observing the resulting deformation of the sample, the Chiaro nanoindenter can quickly provide the mechanical properties of the indented spot. The indentation profile is fully customizable, achieving high precision in maximum load, indentation depth, and deformation rate. Chiaro can perform dynamic mechanical analysis (DMA) to evaluate viscoelastic properties in addition to traditional static indentation for biomaterials.
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Applications/Examples of results
• Evaluate the mechanical phenotype of cell cultures. • Provide the mechanical properties of pathological tissues. • Construct disease models with abnormal mechanical microenvironments such as fibrosis, cancer, and inflammation. • Mimic the in vivo mechanical microenvironment. • Force sensing in contractile cells. • Force sensing during swelling, migration, and proliferation. • Adhesion force spectroscopy. • Cell-material interactions. • Mechanotransduction processes induced by mechanical stimulation. • Study the effects of drugs on the mechanical integrity of 2D and 3D cell cultures. • Evaluate mechanical changes during tissue growth and maturation processes. • Reveal the mechanical effects of new biofabrication methods. • Construct modular tissues with mechanical properties.
Company information
Physio-Machina Co., Ltd. is a company that primarily sells products such as formulation development equipment and dissolution testers, conducts validation and calibration of peripheral devices, and engages in the import and export of software and various equipment. Additionally, it actively provides translation and interpretation of technical documents and seminars, as well as support for the creation of SOPs and conducts training sessions.
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