ＳＵＭＩＣＨＩＲＡＬ ＡＧＰ、ＣＢＨ、ＨＳＡ
This is a high-performance optical isomer separation column in which proteins with optical recognition ability are immobilized on spherical silica gel with a particle diameter of 5 μm. These columns are highly versatile and can separate many optical isomers using a single type of column. <Immobilized proteins (chiral selectors)> AGP: α1-acid glycoprotein CBH: Cellobiohydrolase HSA: Human serum albumin
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basic information
This is a high-performance optical isomer separation column that immobilizes proteins with optical recognition ability onto spherical silica gel with a particle diameter of 5 μm. These columns are highly versatile and can separate many optical isomers using a single type of column. <Immobilized proteins (chiral selectors)> AGP: α1-acid glycoprotein CBH: Cellobiohydrolase HSA: Human serum albumin
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Applications/Examples of results
<Features> - Separation using a reverse phase mobile phase is possible. - SUMICHIRAL AGP is used for the direct separation of a wide range of pharmaceutical optical isomers, including acidic, basic, and neutral compounds. It is often used with acetate-based buffer solutions as the mobile phase and can also be used as a column for LC/MS. - SUMICHIRAL CBH is particularly effective for the separation of optical isomers of basic compounds. - SUMICHIRAL HSA is particularly effective for the separation of optical isomers of acidic compounds. - Selectivity and retention time can be controlled by varying the composition of the mobile phase (pH, concentration, type of solvent, temperature).
Company information
The Sumitomo Chemical Analysis Center has earned the trust of its customers for a quarter of a century as the largest comprehensive analysis company in Japan, possessing high technical skills and expertise in all analytical operations, including environment, electronics, and pharmaceuticals.